双重杂合子

因此认为病人是血红蛋白S和δβ~+地中海贫血基因的双重杂合子。

The patient was considered as a double heterozygote for both haemoglobin S and δβ + thalassemia genes .

结论：双重杂合子红细胞存在两种遗传缺陷，易互相干扰诊断提示。

Conclusion : The diagnostic clues of double heterozygote could be interferenced by two kinds of abnormalities in erythrocyte .

在我国毛难族中发现的1例HbNewYork复合HbE双重杂合子

A Case of Abnormal Hemoglobin Doubly Heterozygous for Hb New York and HbE Found in Maonan Ethnic Group in China

β地贫CD41-42突变杂合子复合缺失型α地贫双重杂合子的基因检测与血液学分析

Gene detection and hematological analysis of β - thalassemia CD41-42 heterozygote compound deletional α - thalassemia

在此基础上，我们对该家庭的中间型地贫高风险胎儿进行了产前基因诊断，结果显示胎儿的基因型与先证者完全相同，为HPFH和β地贫双重杂合子，故建议终止妊娠。

Of six members in this family screened for this type of HPFH deletion , four were positive . Prenatal diagnosis of the fetus showed the same results as that of the propositus .

广东地区β地中海贫血复合缺失型α地中海贫血双重杂合子检出率

The prevalence of β - thalassemia heterozygotes compound α - thalassemia in Guangdong district

溶血系统分析和家系调查可以提高溶血性贫血病因确诊率，尤其对红细胞酶病和双重杂合子具有鉴别诊断意义。

Hemolytic systemic analysis and family survey may improve the etiologically differential diagnosis of hemolytic anemia especially for enzymopathy and double heterozygote .

结果提示，选育双重杂合子转基因后代小鼠，是一条提高转基因动物外源基因表达水平的有效途径。

These results indicated that the selection of double heterozygotes among offspring may be a useful way to improve the expression of exogenous genes in the transgenic animals .

结果表明，相对于单纯杂合子小鼠，纯合子小鼠的表达量无增高（P>0.05），而双重杂合子小鼠的表达量有显著提高（P<0.01）。

The data showed that the hF ⅸ protein expression was not significantly different between homozygotes and heterozygotes ( P > 0 05 ), and their expression in double heterozygous mice was significantly higher than that in heterozygotes ( P < 0 01 ) .

目的：报道β地中海贫血（β地贫）〔－28（A→G）·CD17（A→T）／N〕双重突变杂合子的基因鉴定及家系分析结果。

Objective : To report the result of gene identification and pedigree analysis of the double mutation heterozygote of β thalassemia [ - 28 ( A → G )· CD17 ( A → T ) / N ] .