黄韧带

胸椎黄韧带骨化的影像学研究及其临床意义

Imaging study of the ossification of thoracic ligamentum flavum

黄韧带病变的MRI、CT诊断对比研究

Contrast research of MRI , CT signals of pathological changes of ligamentum flavum

154例黄韧带骨化的MRI诊断研究

Study of MRI in The Diagnosis of 154 Cases of Ossification of Ligamentum Flavum

目的：本文对54例胸椎黄韧带骨化性椎管狭窄患者进行MR和CT对比研究。

Purpose : The purpose of this study was to compare MR with CT images in 54 patients of thoracic spinal stenosis of OLF .

TGF-β1、CollagentypeⅡ和BMP-2在胸椎黄韧带骨化中表达的实验研究

Expression of TGF - β 1 、 Collagen type ⅱ and BMP-2 in the Ossification of Thoracic Ligamentum Flavum

人胸椎黄韧带BMP-2和TGF-β的基因表达增龄性变化

Gene expression of collagen BMP-2 and TGF - β in human lumbar ligamentum flavum

经过统计学分析，颈椎黄韧带切除术与单开门椎管扩大成形术对术后脊髓功能恢复的影响没有显著性差异（P0.05）。

There was no obvious difference in spinal function recovery in the treatment of flavectomy of cervical and unilateral expansive open-door laminoplasty ( P0.05 ) by statistics analysis .

结论：临床表现结合MRI和CT检查，是诊断胸椎黄韧带骨化的重要手段，整块半关节突全椎板切除术为治疗的有效术式。

Conclusion : Clinic history and neurological examination associated with MRI and CT was the important means of the diagnosis of OLF , en bloc hemi-articular process laminectomy was an effective surgical approach .

BMP-2mRNA在实验性黄韧带骨化组织中的表达及其意义

The Expression of BMP-2m RNA in the Tissue of Experimental Ossification of Ligamentum Flavum and Its Significance

方法用盐析法对34个正常黄韧带标本中的Ⅰ型和Ⅱ型胶原含量进行测定，并用SDS-PAGE法进行胶原的分型确定。

Methods 34 cases of normal human ligamenta flava were determined by salt precipitation , the collagen samples were analyzed by SDS - PAGE .

方法1988～1999年收治的18例氟骨症性胸椎黄韧带骨化患者，叙述了临床表现，影像学检查结果（X光平片、脊髓造影、CT及MRI），手术治疗。

Methods We studied eighteen patients who had thoracic ossified ligament turn flavum from 1988 to 1999 . We studied their clinic , radiography which included plain radiographs , myelograms , CT and MRI , operation .

耳中动脉空气栓塞法处死动物后，将腰椎取出，暴露黄韧带，光电镜取材在L5－6。

The rabbits were sacrificed with artery air-embolism . Immediately lumbar were removed and then ligament between L5-6 were resected .

L3-L5黄韧带肥厚症手术治疗二例

Operative Treatment of Hypertrophy of Ligamenta Flava ( L_3 & L_5 ) . Report of Two Cases

结论1、BMP阳性与否反映了骨化黄韧带的成熟与否，其与黄韧带骨化的发生发展密切相关。

Conclusion 1 . The BMP was positive or negative reflect the mature or immature of ossification of ligamentum flavum , it has the relationship with the ossification process .

方法用3H－可溶性胶原底物标记法对11例黄韧带、34例正常椎间盘髓核和35例椎间盘突出症髓核的胶原酶活性进行测定。

Methods 3H labeled soluble collagen substrate was used to determine the collagenase activity in 11 ligament flavum , 34 normal and 35 degenerated nucleus pulposus of lumbar disc .

目的初步探讨胸椎黄韧带骨化（OLF）症再次手术的临床特点。

Objective To study clinical characteristics of re-operation cases of ossification of thoracic ligament flavum ( OLF ) .

方法将大鼠颈曲由下突位变为上突位，在手术显微镜下切开C3、C4间的黄韧带，横断颈髓外侧索；

Methods After the thoracic curve was changed from inferior to superior , the yellow ligment between C3 and C4 and the lateral funiculus were transected under the operating microscope ;

结论：MR图像上脊髓侧后缘异常长T1短T2信号，除为黄韧带肥厚和（或）骨化外，脊椎小关节骨质增生也是一种常见病因。

Conclusion : The causes of abnormal long-T1 and short - T2 imaging in MRI , we think that the osteosclerosis in small joint of spine is a common cause except the subflavous ligament thicken and / or ossify .

手术治疗两例L3～L5黄韧带肥厚症患者，收到满意效果。

Two cases of hypertrophy of ligamenta flava at the L_3-L_5 level undergoing surgical operation were reported , both gaining satisfactory result .

利用有限元软件Ansys的前处理功能，在脊柱模型骨性结构的基础上，补充建立终板、椎间盘、髓核、前纵韧带、后纵韧带、黄韧带、棘间韧带、棘上韧带等结构。

With the pretreatment function of finite element software Ansys the structure of lamina terminalis intervertebral discs nucleus pulposus anterior longitudinal ligament posterior longitudinal ligament ligamenta flava interspinal ligaments supraspinal ligament were established supplementarily based on the osseous structure of spinal model .

结果：脊椎小关节骨质增生13例，黄韧带肥厚和（或）骨化7例，在MR图像上呈长T1短T2信号。

Results : There are 13 cases of osteosclerosis in small joint of spine , and 7 cases of subflavous ligament thicken and / or ossify , all of this display long - Tl and short - T2 imaging in MRI .

结果55例中36例（65.5%）合并胸椎黄韧带骨化（OLF），18例（32.7%）合并颈椎OPLL。

Results 65.5 % of the cases were combined with thoracic ossification of ligamentum flavum ( OLF ), 32.7 % of the cases with cervical OPLL .

目的研究胸椎黄韧带骨化症（OTLF）合并硬脊膜骨化（OD）更有效的诊治方法。

Objective To probe into better diagnosis & treatment method for ossification of the thoracic ligamentum flavum ( OTLF ) and ossification of the dura ( OD ) .

用Woessner法及盐析法测定黄韧带中Ⅰ型与Ⅱ型胶原含量的比值；

The ratio of ⅰ type / ⅱ type collagen was determined by Woessner ′ s method and salting out .

271处黄韧带前间隙＜5mm，其中229处MG示相应腰神经根压迫增粗（90.2%），其诊断腰神经根压迫的敏感性为90.2%，特异性为96.0%，正确性为94.9%。

229 in 271 ( 90.2 % ) lumbar nerve roots were compressed and swollen as demonstrated in MG with the AFLS < 5mm . It 's sensitivity was 90.2 % , specificity 96.0 % and accuracy 94.9 % in the diagnosis of the lumbar compressed radiculopathy .

但TGF-β1和BMP在退行性腰椎滑脱和腰椎间盘突出症肥厚黄韧带中的表达及作用还不清楚，其新生成胶原的种类尚未完全明确。

However , the expression and the effect of TGF-P 1 and BMP of ligamentum flavum in degenerative lumbar spondylolisthesis and lumbar disc herniation are not clear , and the type of proliferative collagen in the hypertrophic ligamentum flavum of degenerative spondylolisthesis is not known yet .

结果：穿刺针依次经过皮肤、筋膜、棘上韧带、棘间韧带、黄韧带至硬膜外腔，深度约36～75mm，平均深度为546mm。

Results The needle punctured passes through the skin , fasciae , supraspinal ligament , interspinal ligament , yellow ligament , and epidural ranging between 36 ~ 75 mm in the depth with a mean of 54 6 mm .

方法：对比观察颈椎管狭窄症患者组及正常对照组颈椎黄韧带的显微和超微结构变化特点，并用Woessner′s法对其胶原含量进行生化测定。

Method : The microstructures and ultrastructures of the cervical ligamentum flavum were observed in 10 patients with cervical spinal stenosis and 10 normal adults , meanwhile , the contents of collagen in ligaments were determined by Woessner ′ s method .

目的为研究黄韧带骨化致椎管狭窄的机制打下基础。

Objective To study the mechanism of ossification of yellow ligament .

退变黄韧带的病理改变与机制的研究进展

Progress of research in pathologic changes and mechanism of degenerative flavum