高碳酸血症

目的：总结应用允许的高碳酸血症通气疗法治疗慢性阻塞性肺疾病（COPD）患者的临床疗效。

Objective : To evaluate the clinical effect of using permissive hypercapnia ventilation therapy in the treatment of chronic obstructive pulmonary disease ( COPD ) .

据报道海水淹溺型肺水肿（pulmonaryedemaofseawaterdrowning，PE-SWD）是海水溺水死亡的主要原因，其主要病理生理学特点为低氧血症、高碳酸血症和代谢性酸中毒。

According to what was reported the main reason for death of sea-water drowning was pulmonary edema of sea water drowning . Hypoxemia , hypercapnia and metabolic acidosis were the common pathophysiology trait .

高碳酸血症对急性肺损伤时核因子-κB和TNF-α的影响

Effects of hypercapnia on nuclear factor-kappa B and tnf - α in acute lung injury models

COPD患者睡眠时显著的低氧血症和高碳酸血症发生于快动眼睡眠期。

The patients with COPD often exhibit hypoxia and hyper-carbonic acidemia during rapid eye movement phase .

无创正压通气治疗COPD合并急性高碳酸血症性脑病的临床研究

Effect of Non-invasive Positive Pressure Ventilation in Treatment of Patients With COPD Complicated With Acute Hypercapnic Encephalopathy

术前进行心理护理和呼吸训练；术后注意早期活动，加强腹腔镜CO2气腹后的观察、护理，做好皮下气肿、胆漏、出血、高碳酸血症和下肢静脉血栓等术后并发症的观察及护理。

The nursing measures included preoperative psychological nursing and respiratory training , postoperative early ambulation , strengthening the observation and nursing of pneumoperitoneum complications such as subcutaneous emphysema , hypercapnemia , venous thrombosis of lower limb and preventing bile leakage and hemorrhage .

结论：NPPV可明显改善COPD急性加重并Ⅱ型呼吸衰竭患者的气体交换，纠正低氧血症和高碳酸血症，提高抢救成功率。

Conclusion : NPPV can effectively improve the gas ventilation with correcting hypoxia and hypercapnia , and to increase the successful rescue rate in the patients with COPD and type II respiratory failure .

结论机械通气时吸入8%的CO2所致高碳酸血症对ALI动物模型有保护作用，其机制可能与改善了肺力学、减少肺泡中蛋白质渗出，减轻多形核白细胞在肺内的扣押及抑制其活性有关。

Conclusion Hypercapnia induced by inspiring high concentration of carbon dioxide ( 8 % ) has protective effects on ALI rabbits . The mechanisms of protection might be associated with preservation of lung mechanics , reduction in alveolar protein and attenuation of PMN sequestration .

探讨经鼻压力支持通气（PSV）治疗Ⅱ型呼衰的效果及对可允许高碳酸血症通气（PHV）治疗的指导意义。

To Study management of respiratory failure tape I through nasal mask pressure support Ventilation ( PSV ) and guiding signif cation by concepts of permissive hypercapnia ventilation ( PHV ) .

方法50例ARDS患者按随机表法分为PCV组和VCV组进行机械通气治疗，均实行允许高碳酸血症策略和肺开放策略，比较两组患者呼吸力学、血气及血流动力学各指标的变化。

Methods Fifty patients with ARDS were randomly divided into PCV and VCV groups with permissive hypercapnia and open lung strategy . Changes in respiratory mechanics , blood gas analysis and hemodynamics were compared between two groups .

结论：肺气肿肺气虚证大鼠存在低氧血症和高碳酸血症，血中细胞因子IL6、IL8、TNFα升高，可能是肺气虚证从轻度向中、重度发展的重要原因之一。

Conclusion : Rats with Lung Qi deficiency syndrome have lower oxygen , lower hypercapnia , higher IL 6 , higher IL 8 and higher TNF α, which perhaps is one of the importance factors that lung Qi deficiency syndrome aggravates gradually .

结果2组患者术后均出现了低氧血症和高碳酸血症。

Results The patients in both groups suffered hypoxaemia and hypercapnia .

甲状腺激素替代治疗后可改善低氧和高碳酸血症。

The hypoxia and hypercapnia ameliorated after thyroid hormone therapy .

容许性高碳酸血症对急性肺损伤动物心肺功能影响的观察

Effects of permissive hypercapnia on cardiopulmonary function in acute lung injury model

高碳酸血症的脑微循环研究

A Study on the Hypercapnia in the Brain Microcirculation

大鼠高碳酸血症模型的复制及其病理生理变化的实验研究

Experimental study on setting up hypercapnic model and its pathophysiological changes in rats

容许性高碳酸血症机械通气治疗重症支气管哮喘

Permitting hypercapnia mechanical aeration treatment for severe bronchial asthma

慢性阻塞性肺疾病患者高碳酸血症与肺功能关系的探讨

Hypercapnia and pulmonary function in chronic obstructive lung disease

危重哮喘允许性高碳酸血症通气的应用

The Application of Permissive Hypercapnia Ventilation in Critical Asthma

急性实验性高碳酸血症的微循环障碍

An Acute Experiment on Hypercapnia with Microcirculatory Stasis

高碳酸血症对兔急性呼吸窘迫综合征保护作用的实验研究

Experimental study on protective effects of hypercapnia to rabbits with acute respiratory distress syndrome

应用允许的高碳酸血症通气疗法治疗19例慢性阻塞性肺疾病

Treatment of 19 patients with chronic obstructive pulmonary disease by using permissive hypercapnia ventilation therapy

允许性高碳酸血症对重度急性呼吸窘迫综合征肺力学特征的影响

Effects of permissive hypercapnia on pulmonary mechanics in patients with severe acute respiratory distress syndrome

用允许性高碳酸血症并机械通气治疗急性呼吸窘迫综合征疗效观察

Observation on therapeutic efficacy of mechanical ventilation with permissive hypercapnia treating acute respiratory distress syndrome

气管内吹气对急性高碳酸血症家兔血气及呼吸力学的影响

Effects of tracheal gas insufflation on blood gases and respiratory mechanics in acute hypercapnia rabbits

内镜下甲状腺切除术中高碳酸血症的预防

Prevention of hypercarbia during endoscopic thyroidectomy

结论：抗凝治疗可降低血液粘度，疏通微循环，缺氧和高碳酸血症得以改善，有利于病情好转。

Conclusion : Anticoagulant therapy can decrease blood viscosity and improve microcirculation , hypoxemia and hypercapnia .

显著高碳酸血症58例次分析

Analysis of 58 Apparent Hypercapnia Cases

1例腹腔镜胃肠手术并发高碳酸血症的急救与护理

Rescuing and nursing care of a case underwent gastrointestinal operation via laproscope and complicated with hypercapnia

小潮气量低气道压允许性高碳酸血症通气策略抢救成人呼吸窘迫综合征

The ventilatory strategy of low tidal volume as well as limited pressure with permissive hypercapnea in ARDS