骺板

大鼠胫骨骺板软骨细胞P物质的表达

Expression of substances P in chondrocyte of rat 's tibia epiphyseal plate

目的：探讨MRI在评价骨肉瘤侵袭骨骺中的价值。方法：复习13例骺板未闭骨肉瘤的MRI、X线平片所见，与病理组织学相对比。

Objective : To study the value of MRI for detecting the epiphyseal extension of osteosarcoma .

研究P物质（SubstanceP，SP）在不同年龄大鼠骺板软骨细胞中的表达。

To investigate the expression of substance P ( SP ) in chondrocytes of rat 's epiphyseal plate .

在骺板的静止区Bax的免疫反应阳性物在软骨的细胞质中表达；

Bax expression was observed in the resting chondrocytes of epiphysis ;

Bax蛋白在骺板软骨细胞中的表达

Expression of Bax Protein in the Cartilage Cells of Epiphyseal Plate

结果：本组所有患者骺板未闭合，与病理组织学所见比较，发现MR诊断骨肉瘤侵袭骨骺的准确率为100%；

Results : The ( epiphyseal ) plates were not closed in all the cases , and the diagnosis rate of MRI was 100 % .

抑癌基因Rb在正常骺板软骨组织中的表达

Expression of tumor suppressor gene Rb in normal cartilage tissues of epiphysis

骨肉瘤侵袭骺板的MRI表现与BMP-2表达及其临床意义

The MRI feature of epiphyseal plate invaded by osteosarcoma and its bone morphogenetic protein-2 expression

目的研究凋亡相关基因Bax在正常骺板软骨细胞中的表达。

Objective This experiment was designed to investigate the expression of Bax in the chondrocytes of the epiphyseal plate cartilage .

CGRP对骺板生长发育影响及其调控机制的实验研究

Experimental Study on the Growth and Development of Epiphyseal Plate and Its Control Mechanism under the Influence of CGRP

雌激素对小鼠骺板AgNORs的影响

Effect of estrogen on AgNORs in epiphyseal plate of mouse

切除部分Ranvier区对骺板软骨细胞bcl-2和bax表达的影响

Expression of bax and bcl-2 in the Chondrocytes of the Epiphyseal Plate Cartilage by Excised the Groove of Ranvier

MCM与正常细胞（兔关节骺板细胞RGP2）共同培养后，细胞增殖无下降。

The proliferation of normal cells ( RGP-2 rabbit joint epiphysial disk cells ) was not affected by MCM .

研究动态压应力对体外培养的大鼠骺板软骨细胞外基质以及甲状旁腺激素相关蛋白（PTHrP）mRNA表达的影响。

To study the effect of dynamic compressive force on mRNA expression of parathyroid hormone-related peptide ( PTHrP ) and chondrogenic extracellular matrix in rat growth plate chondrocytes in vitro . 3 .

3周围神经损伤后，骺板局部CGRP等神经肽分布减少，影响骺板正常发育，导致肢体短小畸形、骨质疏松。

The distribution of neuropeptides ( such as CGRP ) decrease after the brachial plexus injury , affect the development of epiphyseal plate , and cause the limb short , malformation and rarefaction .

结果裸鼠骺板两侧、骨膜内面及松质骨的成骨细胞和破骨细胞可见多量βgal的表达。

Results The osteoblast and osteoclast beside the growth plate , or in the cambial layer of periosteum and cancellous bone , could express a large amount of β - gal.

与模型组比较，中药复方大、中、小各剂量组胫骨干的骺端骺板和骺板下3mm处的骨皮质厚度均有不同程度的增加（P0.01或P0.05）；

All the three doses groups of the prescription could increase cortex at either epiphyseal plate of tibial shaft or 3 mm under it ( P0.01 or P0.05 ) compared with the tail suspended group .

移植24周时对照组为（54.25±18.33）°，人工骺板软骨移植组为（11.27±5.1）°，对照组与人工骺板软骨移植组相比差异均有显著性（P0.01）。

( 54.25 ± 18.33 )° in control group ,( 11.27 ± 5.1 )° in artificial epiphyseal plate group 24 weeks after transplantation . There was significantly difference between control group and artificial epiphyseal plate group ( P0.01 ) .

目的：分析比较X线、MRI两种不同影像学检查方法显示骨肉瘤骺板受侵的阳性率并从分子生物学水平探讨骨形态发生蛋白&2（BoneMorphogeneticProtein-2，BMP-2）与骨肉瘤侵袭可能的关系。

Objective : To discuss the relationship between BMP-2 ( bone morphogenetic protein-2 ) protein and possible mechanism and compare the validity of two different imaging examinations ( radiograph and MRI ) displaying the epiphyseal plate extension of osteosarcoma .

4周时构建软骨的组织结构与天然骺板软骨相类似，硫酸GAG含量平均为天然骺板软骨的34%以上。

In the 4th week , the engineered cartilage resembled the nature epiphyseal plate in the characteristic of histological structure , and had over 34 % of the sulfate GAG content of the natural epiphyseal plate .

结论：1周围神经系统对骨骼生长发育起重要调节作用，骺板生长发育过程中CGRP的分布与骨代谢能力密切相关，表明，CGRP在骺板发育过程中发挥重要作用。

In the process of the development of epiphyseal plate , the distribution of CGRP is concerned with the capability of bone metabolism , so , CGRP plays an important role in the growth and development of epiphyseal plate . 2 .

目的建立定量检测体外培养软骨细胞外基质中糖胺多糖（GAG）含量的方法，以评价体外培养骺板、关节及肋软骨细胞的生物学功能活性。

Objective To establish a method for quantitative detection of the sulfate glycosaminoglycans ( GAG ) content in extracellular matrix of in vitro cultured chondrocytes so as to evaluate the biological characteristics of epiphyseal , articular and rib chondrocytes .

ZnT1及游离锌离子在小鼠骺板软骨细胞的定位研究

Localization of Zinc Transporter 1 ( ZnT1 ) and Free Zinc Ions in Mouse Epiphyseal Growth Plate Chondrocytes

适当的动态压应力能有效促进体外培养的大鼠骺板软骨细胞Ⅱ型胶原及AggrecanmRNA表达，PTHrP在此细胞力学信号响应过程中可能起重要作用。

Moderate dynamic compressive forces promote the expression levels of type ⅱ collagen , aggrecan mRNA in rat growth plate chondrocytes in vitro , and propose that the PTHrP may be an important mediator in signal transduction from biomechanical stimuli . 3 .

方法对118例单侧Perthes病患儿，测定在疾病不同时期的骨龄变化，并将其与骨骺受累程度及骺板是否受累做相关分析。

Methods The bone age of the left wrist of 118 cases with LCPD in different stages was measured on the X ray films according to Chinese standard of carpal bone development . The correlation of involvement of epiphysis with the growth plate was analyzed .

结果氟中毒大鼠骨组织中BMP-2、BMP-7、TGF-β1mRNA表达持续高于对照组，蛋白主要表达在骺板软骨增生期和肥大期细胞、关节软骨细胞、成骨细胞以及韧带细胞等部位。

Results The expression of BMP-2 , BMP-7 and TGF - β 1 mRNA remained at high level in rats treated with sodium fluoride and these proteins mainly appeared in hyperplastic zone and hypertrophic zone of epiphyseal plate cartilages , articular cartilage cells , osteoblasts and ligament cells .

目的研究骺板软骨细胞冻存的方法。

Objective To study frozen reservation method of epiphyseal plate chondrocyte .

骺板软骨细胞复合生物凝胶体外培养生成软骨组织的实验研究

Cartilage regeneration from epiphyseal chondrocytes cultured in biological gel in vitro

家兔骺板直接损伤的影像病理动态研究

A dynamic imageo-pathologic study for the direct physeal injury in rabbits

骺板软骨细胞的体外培养及鉴定

In vitro culture and identification of chondrocytes from the epiphyseal plate