骨基质

超临界CO2制备骨基质/PLA骨修复材料及其表征

The Preparation and Characteristic Evaluation of Bone Matrix / PLA Bone Repair Material by Supercritical CO_2 Fluid Technique

异种骨基质明胶（BMG）的抗原性研究

A study on antigen of heterogeneous bone matrix gelatin

C组：单纯脱细胞骨基质支架材料修复；

In group C , only the scaffold material was implanted .

SD大鼠骨基质明胶吸附骨髓间充质干细胞修复骨缺损的实验研究

A study on repairing of tibial defect of the SD rat with bone marrow mesenchymal stem cells combined with bone matrix gelatin

作者利用羊骨基质明胶（BMG）修复了20只大鼠的洞性骨缺损。

The tibial cavity defects in 20 rats were repaired with sheep BMG .

陶瓷颗粒填充PTFE聚合物基复合材料摩擦磨损特性研究不同比例脱钙骨基质颗粒和骨水泥复合填充物的实验研究

Research of Abrasion Behavior of Composites Consisted of PTFE Polymer Matrix and Ceramic Particles ; The Experimental Study of Different Component Proportions of DBM / BC Composition

目的：探讨骨基质明胶（BMG）防治人工关节无菌性松动的可行性。

Objective : To prevent aseptic loosening after artificial joint replacement by bone matrix gelatin ( BMG ) .

为证实不同形式的脱钙骨基质（DBM）及未脱钙骨的成骨作用进行了本实验。

This experiment was designed to evaluate the osteogenetic effects of different forms of allogenic decalcified bone matrix ( DBM ) .

OB有形成骨骼、调节细胞外骨基质成分的构成以及骨基质矿化的功能。

OBs to form bone there is to regulate extracellular matrix composition of bone as well as the function of bone matrix mineralization .

目的通过同种异体骨基质明胶（BMG）在腰椎间诱导成骨的实验结果，证明同种BMG能够在椎间诱导成骨，达到椎间融合的目的。

Objective To testify the inductive osteogenesis of allogeneic bone matrix gelatin ( BMG ) in promoting intervertebral fusion .

hBMP-2转染自体兔骨髓基质细胞附和异体兔脱钙骨基质的成骨实验研究

Bone Repairing Study of hBMP-2 Transfected rMSCs Attached to DBM

目的探讨海绵状脱钙骨基质（DBM）和泥灰状DBM修复骨缺损的能力。

Objective To evaluate the osteogenic effects of of spongy and putty-like demineralized bone matrix ( DBM ) in repairing segmental defects .

目的：研究以骨髓基质干细胞（BoneMarrowStemCells，BMSCs）为种子细胞，海绵状脱钙骨基质（Demineralizedbonematrix，DBM）为细胞载体的组织工程块修复骨缺损的能力。

AIM : To study the ability of tissue engineering section to repair bone defects with bone marrow stromal stem cells ( BMSCs ) as seed cells and demineralized bone matrix ( DBM ) as cell carrier .

目的制备山羊脱钙骨基质（decalcifiedbonematrix，DBM），研究其物理和生物力学特性，为其作为理想的组织工程骨支架材料提供理论依据。

Objective To prepare completely decalcified bone matrix ( DBM ) and study its physical characteristics and biomechanical properties in order to afford theoretical base for DBM as ideal scaffold of bone tissue engineering .

结果：①骨基质材料的SEM特征骨组织经NaOH消蚀及超声震荡清洗后，细胞成分被彻底消蚀掉。

Results :① SEM characteristic of the bone extracellular matrix material : Maceration of the bone tissues with a NaOH solution followed thorough washing by distilled water and USW effectively and sheerly removed the cellular elements .

目的：检验珊瑚（NC）、异体脱钙骨基质（DBM）、自体骨髓（AM）复合可注射骨替代材料的异位诱导成骨能力。

? Objective : To evaluate the osteoinductive potential of an injectable bone substitute consisting of natural coral ( NC ), allogeneic demineralized bone matrix ( DBM ) and autogeneic marrow ( AM ) .

目的研究兔自体骨髓间充质干细胞（MesenchymalStemcells，MSCs）向软骨细胞方向诱导后复合自体双相骨基质明胶（bonematrixgelatin，BMG）对膝关节软骨缺损的修复作用。

Objective To study the effect of the repair of rabbit articular cartilage defects by the composite of chondrogenic induction of autologous marrow mesenchymal stem cells ( MSC_s ) and autologous " two-phase " bone matrix gelatin ( BMG ) .

目的探讨载药骨基质明胶（BMG）修复节段性骨缺损及防治术后感染的可能性。

Objective To explore the possibility of repair long segmental bone defects and preventing infection with cefazolin loaded bone matrix gelatin ( C BMG ) .

目的探讨异种骨基质明胶（bonemartrixgelatin，BMG）复合带锁髓内钉治疗骨折愈合障碍的可行性。

Objective To investigate the possibility of treatment of fracture union disorder by the combination of bone matrix gelatin ( BMG ) and cross-lock intramedullary nail .

本文用X线和组织学方法，研究了同种骨基质明胶（BMG）对24只家兔和大鼠胫骨缺损的修复效果。

The . tibial defect repaired with allogenic bone matrix gelatin ( BMG ) in 24 rats and rabbits was studied by the radiographic and histological method .

矿化骨基质中，BSP、OPN的高表达率（81.4%、76.7%）显著高于OC（4.6%）。

In mineralized neoplastic bone matrix the high positive rates of BSP , OPN ( 81.4 % , 76.7 % ) were significantly higher than that of OC ( 4.6 % ) .

目的：利用缓降解骨基质明胶（BMG）修复喉框架缺损，以达到恢复喉的外形和功能的目的。

Objective : Using delayed degradation bone matrix gelatin ( BMG ) to repair the defect of laryngeal frame for the goal of laryngeal external form and function recovery .

聚乳酸和无活性脱钙骨基质载体对rhBMP-2异位诱导骨形成的比较性研究

Comparison of inactive demineralized bone matrix and polylactic acid as carriers for recombinant human bone morphogenetic protein 2 ( rhbmp 2 ) induced ectopic bone formation

人甲状旁腺激素（ParathyroidHormone）是体内调节钙磷平衡的一种重要多肽类激素，能够促进骨质的形成，增加骨基质密度，是治疗骨质疏松症的有效蛋白药物。

Human Parathyroid Hormone ( hPTH ) is an important peptide hormone regulating calcium and phosphorus balance . It has been proved to have an important effect on bone formation and increases bone matrix density . It is an important protein drug treating osteoporosis .

结论：NBM是一种新研制的有机无机复合类骨基质材料，具有网状孔隙结构；

Conclusion : NBM is a new compound bone matrix material constituted of organic and inorganic materials , which pocesses a morphological structure of three dimensional foam .

二者具有统计学差异性（P0.05）。结论体外构建的P24/PLGA-[ASP-PEG]仿生骨基质材料是一种理想的组织工程支架材料，能诱导启动典型的软骨内化骨过程，促进骨缺损的修复。

And there was statistical difference between group A and B ( p0.05 ) . Conclusion This novel biomimetic material P24 / PLGA - [ ASP-PEG ] is an ideal scaffold for bone tissue engineering , which can trigger typical os endochondrale procession and improve repair of bone defect .

目的：用99mTc-MDP放射性核素观察同种异体骨基质明胶与部分脱蛋白异种骨复合移植修复兔下颌骨缺损。

Objective : To investigate composite grafts of allogeneic bone matrix gelatin and partially deproteinized xenogeneic bone in the rabbit mandibular defects with 99m Technetium methylene diphosphonate .

1983～1992年应用同种脱钙骨基质（DBM）、骨基质胶（BMG）共368例。男性232例，女性136例。

From 1983 to 1992,368 patients ( 232 male and 136 female ) with an average age of 30.4 years were treated with homogenic decalcified bone matrix ( DBM ) and bone matrix gelatin ( BMG ) .

方法以兔腰椎间盘摘除后的椎间隙作为动物模型，分别植入明胶海绵、同种BMG、脱钙骨基质和酒精保存骨。

Methods The gelatin sponge , allogeneic BMG , decalcified bone matrix ( DBM ) and alcohol conserved bone were implanted respectively into the intervertebral space of rabbit , whose intervertebral discs were removed before implantation .

目的观察不同接种密度对骨髓间充质干细胞（MSCs）与冻干脱钙骨基质（FDBM）体外构建组织工程骨的影响，以选择适宜的接种密度。

Objective To observe the effects of different seeding densities on formatting tissue engineering bone in vitro with freeze-dried demineralized bone matrix ( FDBM ) and mesenchymal stem cells ( MSCs ) .