金属蛋白酶抑制剂

基质金属蛋白酶抑制剂强力霉素对大鼠急性心肌梗死后左心室重构和功能的影响

The Beneficial Effect of Matrix Metalloproteinase Inhibitor Doxycycline on the Prevention of Left Ventricular Remodeling After Acute Myocardial Infarction in Rat

根据它们作用于酶的类型，分为丝氨酸蛋白酶抑制剂、半胱氨酸蛋白酶抑制剂、天冬氨酸蛋白酶抑制剂和金属蛋白酶抑制剂。

According to the different enzymes inhibited , the inhibitors are generally classified into four types : serine proteinase inhibitor , cysteine proteinase inhibitor , asparagine proteinase inhibitor and metalloproteinase inhibitor .

金属蛋白酶抑制剂在喉鳞癌中的mRNA表达及意义

Expression of metalloproteinase inhibitors mRNA in laryngeal squamous cancer and its significance

明胶酶B及其组织金属蛋白酶抑制剂与食管癌生物学行为的关系

Relationship Between Gelatin B as well as Its Tissue Inhibitor of Metalloproteinase and the Biological Behavior of Esophageal Squamous Cell Carcinoma

转染金属蛋白酶抑制剂2基因对损伤血管平滑肌细胞核因子-κB和蛋白激酶C的影响

Effect of transfected tissue inhibitor of metalloproteinase-2 on nuclear factor - κ B and protein kinase C of the injured rabbit vascular smooth cells

应用外源性基质金属蛋白酶抑制剂治疗可能会成为UC治疗的新途径。

Treatment with matrix metalloproteinase inhibitors could be a new way in treating UC .

人组织型基质金属蛋白酶抑制剂-1在Pichiapastoris酵母中重组表达研究

The Expression and Characterization of Human Tissue Inhibitor of Metalloproteinase-1 in Pichia pastoris Yeast System

金属蛋白酶抑制剂EDTA抑制其活性。

The optimal pH of metalloproteinase is pH 7-9 . The activity of the metalloproteinase was inhibited by EDTA .

其活性受到特异性金属蛋白酶抑制剂（TIMP）的抑制。

Their activities are inhibited by the tissue inhibitor of metalloproteinase ( TIMP ) .

而所有MMPs的活性均可被相应的组织金属蛋白酶抑制剂（TIMPs）所抑制。

MMPs are all inhibited by tissue inhibitors of matrix metalloproteinase ( TIMPs ) .

目的：采用超声心动图观察大鼠心肌梗死（MI）模型中外源性基质金属蛋白酶抑制剂多西环素对左心室功能的保护作用。

Objective : Protection of doxycycline ( extragenous inhibitor of matrix metalloproteinases ) on cardiac function was observed following myocardial infarction in rats by echocardiography .

从人新鲜的胎盘组织中提取总RNA，以RT－PCR法获取了人组织金属蛋白酶抑制剂－3（TIMP－3）成熟蛋白的cDNA。

We have isolated the cDNA encoding the mature tissue inhibitor of metalloproteinase 3 ( TIMP 3 ) by using RT PCR method with total RNA extracted from human fresh placenta .

MMPs是ECM降解的主要酶类，基质金属蛋白酶抑制剂&1（tissueinhibitorofmetalloproteinase-1，TIMP-I）是其重要的抑制剂。

On the other hand , MMPs is the main enzymes to degrade ECM . Tissue inhibitor of metalloproteinase-1 ( TIMP-1 ) is the main inhibitor of MMPs .

组织金属蛋白酶抑制剂-1（tissueinhibitorofmetalloproteinase-1，TIMP-1）为前二者的抑制因子，对ECM降解过程起负性调控作用，从而抑制肿瘤的浸润转移。

Tissue inhibitor of metalloproteinase-1 ( TIMP-1 ) is inhibitor of MMPs , which operated a negative adjustment in the degrading of ECM , thereby inhibited tumor invasion and metastasis .

组织金属蛋白酶抑制剂TIMP-2基因转染对胃癌细胞体内外侵袭能力的影响

The effect of tissue inhibitor of metalloproteinase 2 gene ( TIMP 2 gene ) on gastric carcinoma cells in vitro and in vivo

目的探讨组织金属蛋白酶抑制剂（TIMP）在食管鳞癌中的表达及其临床意义。

Objective To investigate the expression of the tissue inhibitor of metalloproteinases ( TIMP ) in human esophageal squamous cell carcinoma ( ESCC ) .

基质金属蛋白酶抑制剂因子（TIMPs）是它的内源性抑制剂，二者共同调节血管的渗透性。

The endogenous tissue inhibitors to metalloproteinases ( TIMPs ) can inhibit their activities . Both MMPs and TIMPs modulate capillary permeability .

目的探讨明胶酶A、B（MMP-2、9）及组织金属蛋白酶抑制剂-1、2（TIMP-1、2）在衰老大鼠肾组织中的表达及它们在大鼠肾脏衰老过程中的作用。

Objective To study the expression and effect of matrix metalloproteinase A , B ( MMP-2 , 9 ) and it 's tissue type inhibitor of metalloproteinases-1 , 2 ( TIMP-1 , 2 ) in kidneys of aging rats .

应用金属蛋白酶抑制剂和蛋白合成抑制剂分别提高和降低Hp介导的T细胞凋亡，以证实其与FasL合成的关系。

Metalloprotease inhibitor , 1 , 10-Phenanthroline ( PHE ) and protein synthesis inhibitor , emetine , were used to change the activity of FasL to confirm the association of FasL with H. pylori mediated killing toward T cells .

蛇毒金属蛋白酶抑制剂（BJ46a）在毕赤酵母系统中的表达、纯化和生物学活性分析

The Expression , Purification and Activity Analysis of Snake Metalloproteinases Inhibitor ( BJ46a ) in Pichia Pastoris

体内还存在天然的组织金属蛋白酶抑制剂（TIMPs），可以抑制所有MMPs的活性，影响肿瘤的侵袭和转移等过程。

On the other hand , there is a kind of tissue inhibitor of metalloproteinases ( TIMPs ) in vivo , which can inhibit the activities of MMPs and hold back the invasion and metastasis of carcinoma .

目的研究广谱基质金属蛋白酶抑制剂多西环素对卒中易感型自发性高血压大鼠（SHR-SP）脑血管系统基质金属蛋白酶的作用，探讨多西环素对脑卒中的发病率及病死率的影响。

Objective To investigate the effects of doxycycline on cerebral matrix metalloproteinases ( MMPs ) in stroke-prone spontaneously hypertensive rats ( SHR-SP ) , and its contribution to stroke incidence , mortality rate and stroke volume in SHR-SP.

目的：合成基质金属蛋白酶抑制剂伊洛马司他。

Objective : To synthesize ilomastat , a matrix metalloproteinase inhibitor .

基质金属蛋白酶抑制剂引起大鼠流产的实验模型

Rat Model of Abortion Induced by Matrix Metalloproteinases Inhibitor 1,10-phenanthroline

基质金属蛋白酶抑制剂和法呢基转移酶抑制剂则疗效欠佳。

While matrix-metalloproteins inhibitors and famesytranferase inhibitors have poor effect .

从天然产物中筛选并表征基质金属蛋白酶抑制剂的研究

Screening and Characterization of Matrix Metalloproteinase Inhibitors from Natural Products

基质金属蛋白酶抑制剂对肺缺血再灌注损伤的保护作用

Protective Effect of Matrix Metalloproteinase Inhibitor on Lung Ischemia-reperfusion Injury

基质金属蛋白酶抑制剂作为新型抗肿瘤药物，在肿瘤治疗方面具有良好的开发与应用潜力。

MMPs inhibitors have good development and application prospect as novel anti-tumor pharmacotherapy .

基质金属蛋白酶抑制剂治疗碱烧伤后兔角膜融解的研究

Experimental study on the treatment of corneal melting after alkali burn with GM 6001

蛇毒金属蛋白酶抑制剂基因的合成及杆状病毒表达载体的构建

Gene Synthesis and Construction of Baculovirus Expression Vector of a Snake Venom Metalloproteinase Inhibitor