酰基转移酶

树鼩卵磷脂胆固醇酰基转移酶cDNA和蛋白质序列结构分析

Analysis of Lecithin-cholesterol Acyltransferase cDNA and Protein Sequence from Tree Shrew

北京鸭卵磷脂胆固醇酰基转移酶的cDNA和蛋白质的结构分析

The Structure of Lecithin ∶ Cholesterol Acyltransferase ( LCAT ) cDNA and Its Protein from Beijing Duck

头孢菌素C酰基转移酶在顶头孢霉中的表达

Expression of Cephalosporin C Acylase in Acremonium chrysogenum

RT-PCR扩增检测肺组织中PC合成限速酶磷酸胆碱二胞苷酰基转移酶（CCTα）mRNA含量；

MRNA content of phosphocholine cytidylyltransferase ( CCT ) in lung explants was investigated in RT-PCR ;

牛磺酸抑制THP-1细胞酰基辅酶A：胆固醇酰基转移酶-1表达

Taurine inhibits expression of acyl coenzyme A cholesterol acyltransferase-1 in THP-1 cells

血管内超声评价新的抗动脉粥样硬化治疗：酰基辅酶A-胆固醇酰基转移酶血管内动脉粥样硬化治疗评估（ACTIVATE）研究的原理和设计

Intravascular ultrasound assessment of novel antiatherosclerotic therapies : Rationale and design of the Acyl-CoA : Cholesterol Acyltransferase Intravascular Atherosclerosis Treatment Evaluation ( ACTIVATE ) Study

人酰基辅酶A：胆固醇酰基转移酶（ACAT）

Human Acyl-coenzyme A : cholesterol Aacyltransferase ( ACAT )

【目的】探讨尿中γ-谷氨酰基转移酶（GGT）的检测在肾病中的意义。

【 Objective 】 To explore the significance of measuring urine γ - glutamyl transferase ( GGT ) in the cases with nephrosis .

ApoAI是高密度脂蛋白（HDL）的主要蛋白成份，大量证据表明，ApoAI可有效地激活卵磷脂胆固醇酰基转移酶（LCAT），在胆固醇逆转运（RCT）过程中起着重要的作用。

Apo AI activates lecithin cholesterol acyltransferase ( LCAT ) and plays an essential role in the reverse transport of cholesterol from peripheral tissues back to the liver , i.

本文谷氨酰基转移酶（GGT，EC2.3.2.2）是从猪肾皮质中提取的。

In this study , Gamma-glutamyltransferase ( GGT , EC2.3.2.2 ) was purified from pig kidney .

为获得不易感动脉粥样硬化动物北京鸭卵磷脂胆固醇酰基转移酶（LCAT）的cDNA和蛋白质序列，分析其结构特点。

To obtain the nucleotide sequence and deduced amino acid sequence of lecithin ∶ cholesterol acyltransferase ( LCAT ) cDNA from Beijing Duck , one kind of anti atherosclerosis animals .

二脂酰甘油酰基转移酶（DGAT；EC2.3.1.20）是催化三脂酰甘油（TAG）合成的最后也是最关键步骤的酶。

Diacylglycerol acyltransferase ( DGAT ; EC 2.3.1.20 ) drives the final and only committed acylation step in the synthesis of triacylglycerol ( TAG ) .

一个Canavan家系天冬氨酸酰基转移酶基因突变分析

Analysis of Aspartoacylase Gene Mutations in One Chinese Family with Canavan Disease

载脂蛋白AⅠ是HDL最主要的结构成分，是卵磷脂胆固醇酰基转移酶的主要激活剂。

Human apolipoprotein A - ⅰ, the major protein component of high density lipoproteins and the main activator of the enzyme lecithin : cholesterol acyltransferase , defines the structure and stability and functions of HDL .

目的：观察牛磺酸对THP-1及THP-1源性巨噬细胞酰基辅酶A：胆固醇酰基转移酶1（ACAT-1）表达及活性的影响。

Objective : To investigate the role of taurine in acyl-coenzyme A : cholesterol acyltransferase-1 ( ACAT-1 ) expression and activity in THP-1 and THP-1-derived macrophages .

目的探讨脑血栓病人卵磷脂胆固醇酰基转移酶（LCAT）活性与脂蛋白成分的相关性。

Objective To explore the relation between the activity of lecithin-cholesterol acyltransferase ( LCAT ) and the composition of lipoprotein in cerebral thrombosis patients .

目的：探讨血清总胆汁酸（TBA）、总胆红素（TBIL）、前白蛋白（PAB）、胆碱酯酶（CHE）及α-谷氨酰基转移酶（GGT）在布-加氏综合征诊断及治疗中的价值。

Objective : To discuss the value of serum total bile acid ( TBA ), total bilibrubin ( TBIL ), pre-albumin ( PAB ), cholinesterase and GGT in diagnosing and treatment for Budd-Chiari syndrome .

目的：研究格列本脲（glibenclamide，优降糖）对酰基辅酶A[胆固醇酰基转移酶（ACAT）]mRNA水平的影响，探讨其对ACAT酶的调节水平。

OBJECTIVE To investigate the effect of glibenclamide on expression of acyl-CoA : cholesterol acyltransferase enzyme ( ACAT ) mRNA , and to discuss its regulating level .

他表示，研究发现了这种寄生虫的一种弱点，就是N-肉豆蔻酰基转移酶（NMT），寄生虫需要NMT来生存。

He says the research a weakness in the parasite . The weakness is an enzyme called N-myristoyl transferase , or NMT . The parasite needs NMT to survive .

目的利用实时定量聚合酶链反应（PCR）法检测巨噬细胞酰基辅酶A：胆固醇酰基转移酶-1（ACAT-1）mRNA的表达。探讨胰岛素和高糖对人THP-1细胞分化的巨噬细胞ACAT-1mRNA表达的影响。

Objective To establish a real-time quantitative PCR for detecting the expression of ACAT-1 ( acyl coenzymeA : cholesteryl acyltransferase-1 ) gene in THP-1-derived macrophages , to evaluate the impact of glucose and insulin on ACAT-1 mRNA expression in THP-1-derived macrophages .

目的：研究单核或巨噬细胞转分化和泡沫细胞形成过程中瘦素对人酰基辅酶A：胆固醇酰基转移酶（ACAT1）表达的影响。

Objective : To investigate the effects of leptin on expression of acyl-CoA : cholesterol acyltrans-ferases_1 ( ACAT_1 ) during the monocytes_macrophages transdifferentiation and foam cells formation .

Patatin-like蛋白作为一种新发现的脂肪分解酶家族，具有酯酰水解酶（Lipidacylhydrolase；LAH）、酯酶和酰基转移酶（蜡合酶）的活性。

As a new family of lipolytic enzyme protein , patatin-like proteins have several activity of acyl hydrolase with esters ( Lipid acyl , hydrolase ; LAH ), esterase and acyltransferase ( wax synthase ) .

目的研究配体罗格列酮活化的过氧化体增殖物激活型受体γ（PPARγ）对单核/巨噬细胞转分化过程中酰基辅酶A：胆固醇酰基转移酶1（AcylCoA：cholesterolacyltransferases，ACAT1）表达效应的影响。

Objective To investigate the effects of peroxisome proliferator activated receptors ( PPAR γ) activated by rosiglitazone on expression of Acyl CoA : cholesterol acyltransferases 1 ( ACAT 1 ) in differentiation of monocytes macrophages .

山羊乳腺短、中链脂肪酸合成受到FAS中的乙酰/丙二酸单酰基转移酶（Acetyl-CoAandmalonyl-CoAtransacylases，AT/MT）功能域的转酰基作用调控。

Short - and medium - chain fatty acids in goat mammary synthesis are functioned by a transferase reaction in the region of Acetyl-CoA and malonyl-CoA transacylases ( AT / MT ) .

目的建立己糖胺途径的关键酶谷氨酰胺∶6磷酸果糖酰基转移酶（glutamine∶fructose6phosphateamidotransferase，GFAT）抑制剂的细胞筛选模型。

Aim To set up an IR-HIRc cell model for screening the inhibitor of GFAT (( glutamine ∶) fructose-6-phosphate amidotransferase ), the key enzyme in the hexosamine biosynthesis pathway ( HBP ) .

基因克隆和序列分析结果表明该突变基因编码一种BAHD基因家族的酰基转移酶。

The clone of the mutant gene and the analysis of flanking sequence by inverse-PCR revealed that the mutant gene encodes a acyltransferase belong to BAHD family .

半乳糖-3-O-磺酰基转移酶-2（GP3ST）是一个新近克隆的磺酰基转移酶，其生物学功能还不明确。

The Gal : 3-O - sulfotransferase - 2 ( GP3ST ) was a newly cloned sulfotransferase and its biological significance remained unknown .

方法：从猪肾皮质中分离刷状缘微绒毛膜，用正丁醇溶解膜结合的酶，经硫酸铵沉淀，DEAEsephacel、ConASepharose、SephadexG200及抗γ谷酰基转移酶（GGT）免疫亲和层析提纯ALP。

Methods : The ALP purification procedure included isolation microvillus of porcine kidney cortices by solubilization the membrance-binding enzymes with 1-butanol , precipitation with ammonium sulfate , chromatography on DEAE-Sephacel , ConA-Sepharose , Sephadex G-200 and a immuno-affinity column of anti-GGT antibodies .

研究胰岛素对单核/巨噬细胞转分化和泡沫细胞形成过程中酰基辅酶A：胆固醇酰基转移酶-1（ACAT-1）表达的影响，发现胰岛素对ACAT-1酶的活性、蛋白、mRNA表达均有增强作用。

During the monocyte-macrophage differentiation and foam cell formation , the effects of insulin on expression of acyl-CoA : cholesterol acyltransferases-1 ( ACAT-1 ) were investigated . The results showed that insulin increased significantly enzyme activity , protein and mRNA expression of ACAT-1 .

采用比较分子力场分析法（CoMFA）和比较分子相似性指数分析法（CoMSIA），系统地研究了40个苯并呋喃类N-肉豆蔻酰基转移酶（NMT）抑制剂的三维定量构效关系。

Using comparative molecular field analysis ( CoMFA ) and comparative molecular similarity indices analysis ( CoMSIA ), three dimensional structure-activity relationship ( 3D-QSAR ) studies were carried out on a series of benzofuran N-myristoyl transferase ( NMT ) inhibitors .