软骨化

骨髓基质干细胞软骨化诱导过程中细胞外基质成分的动态性变化

Chondrogenic induction of bone marrow stem cells : a dynamic process of extra-cellular matrix production

DPLL退变过程分为3个阶段：纤维化增厚、软骨化和骨化。

The degenerative process can be divided into three stages : fibrosis , cartilaginification and ossification .

细胞凋亡在家兔正常软骨化骨过程中作用的电镜观察

Transmission electron microscopy observation on the effect of chondrocyte apoptosis on chondral ossification

股骨头再造、TGF-β1在关节软骨化生中发挥作用的研究

The Research on Reconstruction of Femoral Fead and TGF - β on Chondrification of Articular Cartilage

结果表明，面神经管由膜性化骨和软骨化骨共同形成。

The results showed that the facial canal was formed by the membranous ossification and by cartilaginous ossification .

结论颈椎后纵韧带骨化块病灶具有增殖活跃并向软骨化生、骨化的特性；

Conclusion The ossified mass of the cervical posterior longitudinal ligament has a character of continuous proliferation and ossification .

结论：酒精灭活骨通过软骨化骨和膜内化骨的内修复达到愈合，但愈合过程减慢；

Conclusion : Alcohol-induced devitalized bone can heal with internal-repair but slower than the way of the fresh one ;

结果1.裸鼠肌内注射后有异位成骨，其主要为软骨化骨。

Results ( 1 ) Heterotopic osteogenesis was found after intramuscular injection in nude mice , most of which were endochondral ossification .

结果：BMG/CH复合移植是较为理想的骨缺损修复材料，其成骨方式为软骨化骨。

Results : BMG and CH composite was ideal reconstruction material in repair of bone defect . The way of bone formation was endochondral ossification .

骨可沿两种途径发生，即膜化骨和软骨化骨。结论：牙槽突牵张成骨以膜内成骨方式为主，无明显的软骨内成骨现象。

There are two method on the bone growth : intramembrane ossification and endochondral ossification . Conclusions : The formation of new bone is mainly intramembrane osteogenesis along the distraction vector .

将软骨表型化兔MSCs分为空白对照组、诱导组及鹿茸多肽组，用IL-1β诱导细胞凋亡，并用鹿茸多肽干预。

The MSCs differentiated into chondrogenic phenotype were divided into control group , induced group and PAP group , which were induced into apoptosis cells by IL-1 β and treated with PAP .

目的通过观察鹿茸多肽对白细胞介素1β（interleukin1β，IL-1β）诱导软骨表型化骨髓间充质干细胞（Marrowmesenchymalstemcells，MSCs）凋亡的影响，以优化软骨组织工程的种子细胞。

Objective To observe the effect of pilose antler polypeptides ( PAP ) on the apoptosis of rabbit marrow mesenchymal stem cells ( MSCs ) differentiated into chondrogenic phenotype by interleukin 1 β ( IL-1 β) so as to optimize the seeding cells in cartilage tissue engineering .

髋臼软骨参数化曲面模型

A Parametric Surface Model of Acetabular Cartilage Surface

为了提高髋关节模拟研究精度，提出一种基于逆向工程技术建立和验证髋臼软骨参数化曲面模型的新方法。

In order to improve the precision of the current computer simulation study of hip joint , a novel acetabular surface model & a rotating ellipsoid model was developed .

结论：研究结果在生物化学上支持椎体骨赘来自于周边关节软骨增殖、化生、钙化和骨化的组织学观察。

Conclusions : This result biochemically supports that the vertebral osteophyte arises from proliferating peripheral articular cartilage , which had been observed histologically .

目的：观察实验性骨关节炎模型兔关节滑液中作为反映软骨基质分解化化射活性的糖胺聚糖和透明质酸含量的变化趋势。

AIM : To observe the changing tendency of glycosaminoglycan and hyaluronan , which can reflect the catabolic activity of cartilage matrix , in joint synovial fluid rabbit model of experimental osteoarthritis .

大骨节病区粮水饲养恒河猴软骨基质成分硫酸化特点研究

Studies on sulfated characteristics of cartilage matrix in rhesus monkey fed on grain and water from KBD endemic areas

体外软骨构建是软骨组织工程产业化发展及临床应用的重要手段。

In vitro construction technology is a key approach to industrialization and clinic application of engineered cartilage .

骨关节病软骨DNA损伤研究之一&关节软骨细胞程序化死亡

Cartilage DNA Damage in Osteoarthritis

目的观察软骨细胞在兔小肠黏膜下层（SIS）上的生长特性，为使SIS作为软骨组织工程化的载体打下基础。

Objective To investigate the biocompatibility of small intestinal submucosa ( SIS ) with cartilage cells and to explore the possibility of constructing tissue engineering cartilage with SIS as the scaffold and cartilage cells as the seed cells .

了解软骨细胞在正常和病理条件下如何响应细胞外力信号及其调节情况，可进一步揭示软骨组织工程化细胞种植的最佳力学环境。

Our understanding of how chondrocytes responds to force loading and adjusts correspondingly can further reveal the best mechanical circumstance for articular cartilage cell implantation .