西咪替丁

丹参提取物F与西咪替丁抗胃窦部粘膜再灌注损伤作用的比较

Comparison of effects of Dan Shen Extract F and cimetidine on reperfusion injury in gastric antrum

本文报道术前肌注西咪替丁对胃液pH和胃容量影响。选择35例全麻手术病人。

The effects of cimetidine on gastric juice pH and volume were examined in 35 cases of surgical patients .

目的探讨西咪替丁对尖锐湿疣（CA）术后复发的预防作用。

Objective To study the preventive role of cimetidine in condyloma acuminatum ( CA ) relapse after operation .

静注西咪替丁对十二指肠溃疡出血患者24h胃内pH值的影响

Effects of Intravenous Injection of Cimetidine on 24 h Intragastric pH in Duodenal Ulcer Hemorrhage

结果奥美拉唑和西咪替丁观察组与对照组的pH值差异显著，P<0.05。

Result The pH of Omeprazole treatment group and Cimetidine treatment group was significant as against that of control group ( P < 0.05 ) .

西咪替丁为一种H2受体桔抗剂。

Cimetidine is an antagonist of H2 receptor .

结论：西咪替丁能有效减少再障小鼠脾淋巴细胞IFNγ和TNFα的产生。

CONCLUSION : Cim could effectively reduce the production of IFN γ and TNF α from splenocytes of AA mice .

西咪替丁对非酒精性脂肪性肝炎大鼠细胞色素P450的抑制作用

Inhibitory effect of cimetidine on cytochrome P450 in rats with non-alcoholic steatohepatitis

法莫替丁及西咪替丁对Oddi括约肌压力变化的影响

Effects of famotidine and cimetidine on human sphincter of Oddi pressure

目的：法莫替丁（famotidine）是第3代H2受体拮抗剂，其作用为西咪替丁的20倍，雷尼替丁的7.5倍，是治疗消化性溃疡及十二指肠溃疡的强效药物。

Obejective : Famotidine is a new H2-receptor antagonist and very effective in the treatment peptic ulcer and duodenum ulcer .

目的观察口服西咪替丁联合5-氟尿嘧啶（5-Fu）湿敷预防尖锐湿疣（CA）复发的疗效。

Objective To observe the efficiency of combined cimetidine with 2.5 % 5-Fluorouracil ( 5-Fu ) in preventing relapse of condyloma acuminatum ( CA ) .

目的：研究胃肠癌患者围手术期运用西咪替丁（CIM）对肿瘤局部免疫反应的影响。

Objective : To study the effects of perioperative CIM application on the local immune response in gastrointestinal cancer patients .

结论：三种H2受体拮抗剂对壁细胞H2受体脱敏的诱导能力存在一定的差别，其中法莫替丁最强，西咪替丁最弱。

CONCLUSION : Three H2 receptor antagonists can induce different desensitization of the H2 receptor , among which famotidine induces the strongest and cimetidine does the weakest .

结果西咪替丁与双嘧达莫均可延长感染病毒鼠的平均存活天数（P均小于0.05），西咪替丁还可降低小鼠的死亡率（P<0.05），但未观察到随西咪替丁浓度的增加有降低死亡率的特点。

Results Cimetidine and dipyridamole could both elongate the average life time of the mice affected tick borne encephalitis virus ( P < 0.05 ) . Cimetidine could decease the death rate of the mice affected tick borne encephalitis virus ( P < 0.05 ) .

目的比较丹参提取物F（DSEF）与西咪替丁（CI）抗胃窦部粘膜再灌注损伤作用。

Objective To compare the effects of Dan Shen Extract F ( DSEF ) and cimetidine ( CI ) on reperfusion injury in gastric antrum .

西咪替丁为组胺H2受体阻断剂，治疗十二指肠球溃疡疗效显著，但其复发率高，副作用多。

Cimetidinum is a type of H2 receptor antagonist , which is markedly effective in the treatment of gastroduodenal . ulcer , but with many side effects and high recurrence .

为探讨组胺H1受体拮抗剂扑尔敏和H2受体拮抗剂西咪替丁对低温诱发的肉鸡肺动脉高压的影响，并由此推测组胺在低温诱发的肉鸡肺动脉高压形成过程中的作用。

Effect of two histamine receptor antagonists , chlorphenamine maleate and cimetidine , on pulmonary hypertension ( PH ) induced by low ambient temperature in broiler chickens were investigated .

方法：将71例高原昏迷患者随机分为两组，治疗组用西咪替丁800mg/24h，静脉滴注，根据并发上消化道出血情况测定胃液pH值及胃液隐血试验；另一组为对照组；

Method : All 71 subjects were randomly divided into test group ( Cimetidine infusion , 800mg / 24h ) and control group . The level of pH and occult blood in gastric juice and other indices were examined while treatment of high altitude coma .

目的：观察西咪替丁预防新生儿急性胃粘膜病变（AGML）的效果。

Objective : To observe the effect of cimetidine on acute gastric mucosal lesion ( AGML ) of newborns .

应用WHO4d抑制原虫法及〔3H〕－TdR掺入淋巴细胞转化试验，观察西咪替丁（CMD）对感染疟原虫小鼠脾淋巴细胞增殖反应的影响。

The influence of Cimetidine ( CMD ) on the proliferation reaction of spleen lymphocytes of mice infected with plasmodia was observed by means of WHO 4 d inhibition test and lymphocyte transformation assay .

方法：制备乙酸致大鼠胃溃疡模型，分别予健胃汤及西咪替丁治疗13d后，检测胃溃疡粘膜细胞凋亡指数（AI）、增殖细胞核抗原标记指数（LI），并分析细胞周期变化情况。

Methods : Rats with acetic acid-induced gastric ulcer treated with JWD or cimetidine for 13 days , the apoptotic index ( AI )、 proliferating cell nuclear antigen labeling index ( LI ) and cell cycle were detected .

西咪替丁（XMD）是一种H2受体拮抗剂，能特异性阻断组胺H2受体引起的作用。

Cimetidine is one of the H_2 receptor blockers , which could specifically block the effects of H_2 receptor . There have been few foreign reports of Cimetidine 's effects on cellular immune function , and no related domestic reports .

方法选取2004年1月~2005年1月在我院行心瓣膜置换术的30例风湿性心脏瓣膜病患者分为两组，西咪替丁组麻醉后切皮前至术后第5d静脉滴注西咪替丁400mg；

Methods From Jan.2004 to Jan.2005 , thirty patients suffered from rheumatic cardiac valvular disease received cardiac valve replacement in our hospital , and were divided into cimetidine group and control group .

将30例心脏病人随机分为对照组（A组）及预防用药组（B组），观察H1、H2受体阻断剂（苯海拉明、西咪替丁）对抗鱼精蛋白副反应（血压下降）的效果。

Patients with cardiac disorders were randomly divided into two groups ( controls A group , and durg adminstration B group ) . Patients in group A are given protamine . Patients in group B were given protamine and H recepter blockers ( Benadryl and Cimetidine ) .

方法利用流式细胞仪（FCM）结合Fluo3染色技术，半定量检测组胺及H2组胺受体拮抗剂西咪替丁对体外培养HKC胞内Ca2+浓度的影响。

Methods By using flow cytometer ( FCM ) bound with Fluo-3 staining , the effects of histamine and the histamine H_2 receptor antagonist cimetidine on the free intracellular calcium concentration of HKC cultured in vitro , were examined half-quantified .

西咪替丁治疗大鼠非乙醇性脂肪性肝炎

Experimental study on cimetidine in treatment of nonalcoholic steatohepatitis in rats

悬浮聚合法制备西咪替丁印迹聚合物微球的分子选择性能

Molecule Selecting Property of Cimetidine Imprinted Polymeric Microspheres via Suspension Polymerization

西咪替丁对大鼠体内呋喃氟脲嘧啶药代动力学的影响

The influence of cimetidine on the pharmacokinetics of FTORAFUR in rats

复方丹参加西咪替丁治疗过敏性紫癜临床观察

Clinical Observation of Compound Danshen plus Cimetidine in Treating Allergic Purpura

结论：西咪替丁具有一定的终止中孕妊娠作用。

Conclusion : Cimetidine has the effect of anti middle pregnancy .