血浆清除率

非离子型造影剂iohexol血浆清除率单点检测法测定肾小球滤过率

Determination of glomerular filtration rate by non-ionic contrast medium iohexol plasma clearance

目的用非离子型造影剂iohexol血浆清除率检测肾小球滤过率（GFR）。

Objective To evaluate the determination of glomerular filtration rate ( GFR ) by non-ionic contrast medium iohexol plasma clearance .

熟悉血浆清除率的概念及意义。

To be familiar with the concept and its significance of plasma clearance .

IL－2脂质体的血浆清除率明显低于单纯IL－2，其生物利用度明显提高。

The clearance rate of IL-2 liposome in plasma was significantly lower than that of free IL-2 , and the bioavailability of IL-2 liposome was significantly im-proved .

方法：观察同位素标记化学修饰LDL在SR－AI／I基因敲除和正常小鼠血浆的清除率和同位素标记的LDL在体内主要器官的分布。

METHOD : To observe the clearance rate of modified LDL in the plasma of SR-AI / II knockout and control mice .

同时，也降低了CUR血浆总清除率和峰浓度。

Additionally , plasma total body clearance and peak concentration were also decreased .

结果机采血小板经生理盐水洗涤后血浆蛋白清除率99.28%，血小板功能指标与洗涤前相比差异无显著性。

Results The removal of plasma proteins was 99.28 % in washed platelets , And there was no significant difference in platelet functions before and after being washed .

结果显示，抗ApoB抗体的加入加快了LDL在家兔血浆中的清除率；增加了网状内皮系统（如肝、脾组织）和巨噬细胞对LDL的摄取；

The results showed that in vivo the addition of anti-apoB increased both the LDL elimination rate from the plasma and the uptake of LDL by reticulo-endothelial system ( liver , spleen );

结果：血浆VA浓度及清除率在稳态时呈昼夜节律性变化（P<0.01），限定进食时间影响VA动力学的节律，使峰值位相移动约12h。

RESULTS : Plasma VA concentration and clearance at steady-state showed circadian rhythms ( P < 0 . 01 ) . Time-restricted feeding influenced the rhythm of VA kinetics , acrophases of rhythms shifted approximately 12 h.

以双血浆法~（99m）Tc-DTPA血浆清除率为GFR参考值。

Using ~ ( 99m ) Tc - diethylene triamine pentaacetic acid ( ~ ( 99m ) ~ Tc-DTPA ) plasma clearance by dual plasma sampling method as reference GFR ( rGFR ), the original abbreviated MDRD equation was modified by the following two methods .