螺旋细胞

结果表明：藏卵器外的管细胞（包围细胞或螺旋细胞）在卵细胞受精以后，不但没有钙的沉淀、加厚，而且还呈现出逐渐萎缩，最终消失。

The results show that surface tube cells ( surround cells , or spiral cells ) of oogonium , after the egg cell fertilized , not only lack calcareous deposit thickening , but also wither away gradually so that they disappear finally .

结论：水杨酸钠能促进豚鼠螺旋神经节细胞NF-κB蛋白表达；

Conclusion : Sodium salicylate can promote the protein expression of NF - κ B in cochlear spiral ganglion cells .

APE/Ref1在H2O2诱导耳蜗螺旋神经节细胞氧化损伤过程中的表达

Expression of APE / Ref-1 in cultured rat spiral ganglion cells after oxidative damage induced by H_2O_2

人Bcl-2基因重组腺病毒的构建及其在螺旋神经节细胞中的表达

Construction of recombinant adenovirus containing human Bcl-2 and its expression in the spiral ganglion cells

Caspase-3在老年豚鼠耳蜗螺旋神经节细胞的表达

Expression of Caspase-3 in the cochlea of old aged guinea pigs

方法手术分离新生小鼠的耳蜗螺旋神经节细胞进行培养，24h后提取RNA。

Methods The spiral ganglion cells were dissected from cochleae of neonatal mice and cultured for 24 h.

基因转染后24h在荧光显微镜下观察到胞体及轴突发出绿色荧光的螺旋神经节细胞。

The cell bodies and axons of SGCs with green fluorescence were observed by fluorescence microscope .

冲击波对豚鼠耳蜗螺旋神经节细胞Caspase-3的影响及与听阈阈移相关性研究

Expressions of caspase-3 protein in spiral ganglion cell following guinea pigs cochlear damage caused by shock wave

阳离子脂质体介导小鼠原代螺旋神经节细胞NT-3基因转染的实验研究

Cationic liposome mediated NT-3 gene to transfect mice spiral ganglion cells

对基因治疗而言，在KA造成螺旋神经节细胞不可逆损伤之前有一段宝贵的治疗时机。

There is a precious cure opportunity for inner ear gene therapy before the irreversible impairment of cochlear ganglion cells .

结论：气体冲击致豚鼠耳蜗损伤可致耳蜗螺旋神经节细胞发生凋亡并Caspase-3阳性表达，导致听力下降。

Conclusion Cochlear damage caused by air blast could induce the apoptosis of spiral ganglion cell and increase expression of caspase-3 in guinea pigs .

噪声致螺旋神经节细胞损伤的Glu受体机制和Glu受体与ATP受体相互作用的研究

Investigation on the Glu Receptor Mechanism of the Spiral Ganglion Neuron Damage in Acoustic Trauma and the Interaction between Glu and ATP Receptors

结论：1.在暴露于高浓度谷氨酸初期即会引起螺旋神经节细胞内caspase-3蛋白的激活，导致部分神经元细胞凋亡。

At the early stage of exposure to high level glutamate , there is a detectable activation of caspase-3 resulting in apoptosis of neurons . 2 .

腺病毒介导的NT3基因转染对噪音损伤的耳蜗螺旋神经节细胞的保护作用

Adenovirus-mediated NT3 gene transfer protects spiral ganglion neurons from degeneration after noise trauma

目的构建表达人Bcl2基因的重组腺病毒，并研究其在原代培养螺旋神经节细胞（spiralganglioncells，SGC）的表达特性。

Objective To construct the adenoviral vector containing human Bcl-2 gene and to study the expression of the gene in the spiral ganglion cells ( SGC ) in vitro .

方法建立体外培养小鼠耳蜗螺旋神经节细胞的方法，并进行神经丝蛋白（NF）免疫组化染色鉴定及受体酪氨酸激酶C（TrKC）免疫组化染色。

Methods The SGCs were cultured and purged in vitro . SGCs were identified by neurofilament ( NF ) and receptor tyrosine kinase C ( TrKC ) immunocytochemical staining .

庆大霉素作用下豚鼠耳蜗螺旋神经节细胞bcl-2及Bax的表达结果发现，AdV/Calpastatin感染组中耳蜗SGNs的存活数目高于单纯庆大霉素作用组。

Expressions of bcl-2 and Bax protein in guinea pig cochlea following gentamicin administration AdV-calpastatin significantly increased SGN survival in cochlear cultures treated with gentamicin .

NT3基因转染对小鼠耳蜗螺旋神经节细胞生长的影响

The influence of NT-3 transfection in vitro on the growth of mice cochlear spiral ganglion cells

结果：耳蜗毛细胞、支持细胞、螺旋神经节细胞、神经纤维均有bFGF表达，成熟毛细胞表达很弱；

Results : In cochlea , the hair cells , supporting cells , spiral ganglion neurons , and nervous fibers expressed bFGF distinctly . The expression in mature hair cells was slight .

目的在体研究碱性成纤维细胞生长因子（bFGF）对谷氨酸钠所致豚鼠耳蜗螺旋神经节细胞毒性损伤的拮抗作用。

Objective To study the antitoxic effect of basic fibroblast growth factor ( bFGF ) on survival and neurogenesis of the spiral ganglion cell of guinea pig exposed to glutamate in vivo .

Ad-NT3组和KA组均于KA处理后第20天处死，观察Ⅰ型螺旋神经节细胞（传入神经元）的形态变化；

All the animals of Ad-NT3 group and KA group were sacrificed 20 days after KA perfusion for morphological observation of type ⅰ spiral ganglion cells and NT-3 immunoreactivity .

而且Ad-NT3组耳蜗螺旋神经节细胞减少的数量低于KA组（P<0.001）。

The number of degenerated spiral ganglion cells in the Ad-NT3 group was significantly lower than that in the KA group ( P < ( 0.001 )) .

耳蜗组织在正常情况下，血管纹、毛细胞及螺旋神经节细胞均有iNOS弱阳性表达，在缺血及再灌注期间iNOS表达增强。

There is slightly positive expression of iNOS in the hair cell , the stria vascularis , and the spiral ganglion in normal cochlea tissues . The expression of iNOS increased with the severity of ischemia reperfusion .

目的通过神经营养素3（NT3）基因转染的方法，了解NT3对耳蜗螺旋神经节细胞（SGC）生长的影响。

Objective To observe the influence of neurotrophin-3 ( NT3 ) transfection in vitro on the growth of mice cochlear spiral ganglion cells ( SGCs ) .

目的：探讨电针预防庆大霉素对耳蜗螺旋神经节细胞（cochlearspiralganglioncells，SGC）损伤的作用。

AIM : To investigate the effects of electroacupuncture ( EA ) protection on the injury of gentamicin ( GM ) induced cochlear spiral ganglion cells ( SGC ) .

CGRP作用具有双重效应：低浓度可以减少caspase-3的激活，有效地避免螺旋神经节细胞的凋亡；高浓度CGRP可引起剂量依赖的caspase-3激活水平的增加。

CGRP has dual effects on SGNs . CGRP at low concentration could reduce the activation of caspase-3 , and protect the spiral ganglions from apoptosis . However , high concentrations of CGRP cause a dose-dependent increase in caspase-3 activation . 3 .

结论PARP在气体冲击致豚鼠耳蜗螺旋神经节细胞损伤后呈阳性表达，提示耳蜗螺旋神经节细胞凋亡在冲击波致聋的发病机制中起重要作用。

Conclusion PARP masculine reaction staining appeared in guinea pigs damaged cochlear SGC caused by shock wave , cochlear SGC apoptosis may play an important role in cochlear damage caused by shock wave .

目的了解谷氨酸钠致单离培养的小鼠耳蜗螺旋神经节细胞损伤后，碱性成纤维细胞生长因子（bFGF）对其生存及生长的影响，以及二者对细胞内游离钙离子浓度的影响。

Objective To understand the effects of basic fibroblast growth factor ( bFGF ) on survival and neurogenesis of the cultured spiral ganglion cell ( SGC ) of mouse after exposed to glutamate , and the effects of bFGF and glutamate on free intracellular calcium ion concentration .

神经营养素3（neurotrophin3，NT3）作为螺旋神经节细胞特异的营养因子，可有效地支持内耳传入神经元的存活，因此有望成为治疗因其退变而引起的感音性神经性耳聋的有效因子。

Numerous studies have shown that the health of spiral ganglion neurons is highly important for hearing . As a trophic factor of spiral ganglion neurons , neurotrophin 3 ( NT3 ) is a potential candidate for prevention of spiral ganglion neuron degeneration in human .

小鼠螺旋神经节细胞电压依赖性钙通道亚单位分析

Subunit of voltage-dependent calcium channels in the murine spiral ganglion cells