蛙皮素

豚鼠交感神经节非胆碱能迟慢兴奋性突触后电位与蛙皮素、P物质的关系

The Relationship between Non-cholinergic , Late Slow-excitatory Postsynaptic Potential and Bombesin or Substance P in Sympathetic Ganglia of Guinea-pig

目的：探讨蛙皮素（BOM）对离体交感神经节细胞的易化作用。

Objective : To investigate the effect of bombesin ( BOM ) on the facilitation of isolated guinea pig sympathetic ganglia cells .

方法腹腔注射蛙皮素制成AP大鼠模型。

[ Methods ] AP was induced by injection of Cerulein .

方法：用胰胆管内注射甘脱氧胆酸，结合静脉输注蛙皮素方法复制大鼠ASP模型。

Methods : The ASP model was produced by intravenous infusion of cerulein with the combination of intraductal administration of glycodeoxycholic acid .

蛙皮素，胃泌素释放肽（GRP），兔抗。

Bombesin , Gastrin Releasing Peptide ( GRP ), Rabbit anti .

蛙皮素和生长抑素对人胃癌BGC-823细胞生长的影响及受体后信息传递

Effects of bombesin and somatostatin on proliferation of human gastric cancer cell line BGC-823 and their postreceptor signal transduction

结论4℃时蛙皮素能抑制IL-1β发热，其机制有可能是通过抑制cAMP合成或释放实现的。

CONCLUSION : Bombesin can inhibit IL-1 β - induced fever at 4 ℃ , and the mechanism may be related to the inhibition the synthesis and release of cAMP .

此后陆续发现许多与BN结构相似、生物学特性、生理作用相似的物质，统称为蛙皮素样肽。

Bombesin - like peptides which were similar to BN in many respects , such as , structure , biological characteristic , physiological role , etc.

目的：探讨蛙皮素在化学致癌剂N鄄甲基鄄N'鄄硝基鄄N鄄亚硝基胍（MNNG）诱发人胃黏膜上皮永生细胞系GES鄄1癌变过程中的作用。

Aims : To investigate the effects of bombesin on the malignant transformation of immortalized human gastric epithelial cell line GES-1 induced by chemical carcinogen N-methyl-N ′ - nitro-N-nitrosoguanidine ( MNNG ) .

肺癌细胞和蛙皮素抑制树突状细胞的产生和功能

Lung cancer cells and bombesin inhibit dendritic cell generation and function

急性胰腺炎诱导采用蛙皮素腹腔注射，用常规病理评价胰腺的炎症程度；

Acute pancreatitis were induced by intraperitoneal injection of cerulein .

蛙皮素样肽对中枢神经系统的调节作用研究进展

Progress on the Role of Bombesin-like Peptides in the Central Nervous System

阿片样物质；胃泌素释放肽/蛙皮素家族；

The opioids , and the gastrin - releasing peptide / bombesin group ;

蛙皮素抑制失血-感染大鼠肠道细菌移位的实验研究

Effect of bombesin on intestinal bacterial translocation in rats after hemorrhage combined with infection

蛙皮素促进细胞生长及细胞转化的许多机制尚不清楚，与细胞周期调控因子之间的关系亦未见报道。

The mechanism regulating cell growth and proliferation by bombesin is not very clear .

蛙皮素及其同类物与肿瘤的关系

Relationship between Bombesin and Its Analogues and Carcinomas

当外界环境温度不同时，蛙皮素对动物体温的作用不同。

When the outer circumstance temperature altered , function of Bombesin to animals changed too .

蛙皮素对雄激素非依赖型前列腺癌细胞增殖、粘附、迁移的影响

Effect of bombesin on proliferation , adhesion , immigration of human androgen-independent prostate cancer cells line

胃癌、癌旁粘膜中蛙皮素的免疫组化及图像分析研究

A immunohistochemical and image analytic study of bombesin in gastric carcinoma and its adjacent gastric mucosa

这些结果仅提示，蛙皮素的抗溃疡作用可能部分地通过它对迷走中枢紧张性的抑制。

These results suggest thatbombesin might exert its effect partly through the inhibition on vagal tone .

在无血清培养基中，上述受体拮抗剂对人胃癌细胞生长也有直接的抑制，提示蛙皮素对胃癌细胞有自分泌调节作用。

In serum-free medium , bombesin receptor antagonist inhibited the growth of human gastric cancer cells .

本文旨在探讨蛙皮素的降体温及抗热作用机制。

In this study , the mechanism underlying thermoregulatory action of bombesin is to be further elucidated .

小肠刷状缘水解酶与大肠癌蛙皮素对新生兔小肠粘膜刷状缘双糖酶活性的调节作用

The regulatory effects of bombesin on the activities of disaccharidase in the intestinal mucosa in neonatal rabbits

蛙皮素在人胃黏膜上皮永生细胞系化学癌变过程中的作用

Effects of Bombesin on the Malignant Transformation of Immortalized Human Gastric Epithelial Cell Line Induced by Chemical Carcinogen

蛙皮素对新生兔胃肠形态及细胞增殖的调节研究

Study on the Regulatory Effects of Bombesin on the Gastrointestinal Morphology and Proliferation of Mucosa Cells in Neonatal Rabbits

蛙皮素-蜂毒素杂合肽基因在大肠杆菌中的克隆与诱导表达

Cloning and Expression of a Synthetic Gene Encoding Magainin-Melittin Hybrid Peptide in Escherichia coli and Studies on its Antibacterial Activity

目的探讨蛙皮素对新生兔胃肠形态学及胃肠粘膜细胞增殖的调节作用。

Objective To investigate the regulatory effects of bombesin on the gastrointestinal morphology and proliferation of mucosa cells in neonatal rabbits .

结论除生长抑素受体外，胃泌素瘤和肠血管活性多肽瘤还表达胰泌素、蛙皮素、肠血管活性多肽受体。

Conclusions Besides somatostatin receptors , most of gastrinomas and VIPomas also express receptors for bombesin , secretin and vasoactive intestinal peptide .

说明乙酰胆碱和蛙皮素是胃泌素壁内调节机制中两个主要介质。

Showing acetyl choline and frog skin native is gastric secrete element adjust inside the wall two main medium in the mechanism .

蛙皮素对人胃癌细胞株和人胃粘膜上皮永生细胞株生长的影响及作用机制的研究

The Effect of Bombesin on the Growth of Human Gastric Carcinoma Cell Line and Human Immortalized Gastric Epithelial Cell Line and Its Mechanisms