苯妥英
- 网络Phenytoin;dilantin;PhT
![苯妥英](../cache/1193613.jpg)
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HPLC法同时测定人血清中卡马西平、环氧化卡马西平和苯妥英
HPLC Simultaneous Determination of Carbamazepine , Carbamazepine - 10 , 11 - epoxide , Phenytoin in Human Serum
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RP-HPLC同时测定人血清中苯巴比妥、苯妥英、卡马西平的浓度
Determination of Phenobarbital , Phenytoin and Carbamazepine in Serum by RP-HPLC
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方法:应用膜片钳单通道技术记录苯妥英对缺氧大鼠大脑皮质神经元上K(Ca)通道电流活动。
Methods : K ( Ca ) channal current was recorded with patch clamp technique in rat corticocerebral hypoxic neurons .
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IGF-1经PI3K/Akt依赖性途径保护苯妥英诱导的小脑颗粒神经元凋亡
IGF-1 protection against cerebellar granule neurons apoptosis induced by diphenylhydantoin through a PI3K / Akt dependent pathway
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目的:建立HPLC法同时测定血清苯妥英(PHT)与卡马西平(CBZ)浓度。
OBJECTIVE : To develop an HPLC method for quantitative determination of phenytoin and carbamazepine in blood serum .
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服药前后比较,苯妥英锌使大鼠血清HDL-C和HDL-C/TC分别上升8%和17%(p<0.05),(LDL+VLDL)-C下降34%(p<0.01);
Phenytoin zinc could cause HDL-C and HDL-C / TC to increase by 8 % and 17 % . respectively ,( LDL + VLDL ) - C to decrease by 34 % ;
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考察了大鼠口服苯妥英锌或苯妥英钠15mg/(kg·d)45d对血脂的影响。
Rats were treated with phenytoin zinc or phenytoin sodium 15mg / ( kg . d ) for 45d .
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当癫疒间患者身高体重比增加或合并使用苯妥英时VPA动力学参数CL增加。
CL of VPA in epileptic patients will increase if ratio between body height and body weight of epileptic patients rises , or co-administrated with phenytoin .
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报道了电极对苯巴比妥,硫喷妥,异戊巴比妥、苯妥英、利尿酸及水杨酸的电位响应特性及最佳pH与浓度区间。
The potentiometric response characteristics of the electrode with respect to thiopental , phenobarbital , amobarbital , phenytoin , ethacrynic acid and salicylate were studied and the optimum pH and concentration range of the electrode for different organic drugs were found .
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背景与目的:探讨褪黑素(MT)对苯妥英(DPH)诱发小鼠的致畸效应的影响。
BACKGROUND & AIM : To test the hypothesis that antioxidant melatonin ( MT ) can reduce the incidence of phenytoin ( DPH ) induced teratogenesis .
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P4502C9的底物包括甲苯磺丁脲、苯妥英、S法华令、氟西汀、洛沙坦等。
P4502C9 substrates mainly include tolbutamide , phenytoin , S-warfarin , fluoxetine , and losartan .
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目的:探讨苯妥英(DPH)神经发育毒性与胚胎脑组织中自由基产生和氧化应激反应的关系。
AIM : To explore the relationship between the developmental neurotoxicity ( DNT ) induced by prenatal phenytoin ( DPH ) exposure and free radicals and oxidative stress initiated in the embryonic brain .
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苯妥英锌腹腔注射的ED(50)和LD(50)分别为9.74和138.1mg/kg,治疗指数与苯妥英钠接近,刺激性比苯妥英钠小。
ED_ ( 50 ) and LD_ ( 50 ) of phenytoin zinc ip were 9.74 and 138.1 mg / kg respectively . The therapeutic index of phenytoin zinc was closed to that of phenytoin sodium , but its irritability was less than that of later .
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成人癫痫苯妥英个体化治疗的临床意义
Clinical significance of phenytoin in the individual treatment of adult epilepsy
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褪黑素对苯妥英诱发胚胎脑组织氧化性损伤的拮抗作用
Melatonin antagonizes the oxidative damage initiated by phenytoin in embryonic brain
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苯妥英锌对家兔血清高密度脂蛋白胆固醇的影响
Effects of phenytoin zinc on serum high-density lipoprotein cholesterol in rabbits
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幼年家兔口服苯妥英锌7个月小脑生长发育的研究
Development of cerebellum with 7 months orally phenytoin zinc in childhood rabbits
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苯妥英锌对烧伤的临床治疗作用
Clinical observation of phenytoin zinc in the treatment of patients with burns
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基因诊断在苯妥英治疗癫痫病中的应用
Application of gene diagnosis in treatment of phenytoin for epilepsy
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苯妥英外用治疗难愈性创面疗效观察
Observation of the effect of topical phenytoin on intractable wounds
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苯妥英锌抗脂质过氧化及对小鼠缺血心肌的保护作用
Anti-lipid peroxidation and protective effects of phenytoin zinc on mice ischemic myocardium
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苯妥英锌抗实验性癫痫的研究
A Study of Antiepilepsy of Zinc Phenytoin in Experimental Epilepsy
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经期性癫痫苯妥英血药浓度及药动学的周期性变化
Cyclical Variations of Blood Concentration of Phenytoin and Its Pharmacokinetics in Menstrual Epilepsy
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苯妥英锌对癫痫小鼠脑内氨基酸含量的影响
Effects of zinc phenytoin on contents of amino-acids in brain of epileptic mice
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苯妥英锌的制备及初步药理学研究
Preliminary studies on Preparation and pharmacology of zinc phenytoin
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~(125)I-苯妥英放免分析测定盒的质量控制
The quality control of ~ ( 125 ) I - phenytoin RIA kit
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苯妥英局部应用治疗痛风并发难治性溃疡3例
The Effect of Phenytoin on Refractory Ulcers in Gout
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咖啡因对苯妥英诱导的小脑颗粒神经元凋亡的保护作用及机制
Protective effects of caffeine on apoptosis of cerebellar granule neurons induced by diphenylhydantoin
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苯妥英-β环糊精包合物的生物利用度及溶解性能
Bioavailability and dissolution behaviour of the inclusion of phenytoin - β - cyclodextrin
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癫痫病人血清与唾液中苯妥英浓度的测定及相关性研究
Monitoring the Concentration of Phenytoin in Serum , Saliva