膜迷路
- 名membranous labyrinth
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目的为明确哪几种膜迷路蛋白成分参与了实验性自身免疫性内耳病(autoimmuneinner-eardisease,AIED)的形成。
Objective To define the components of membranous labyrinth proteins which take part in the development of autoimmunity in experimental animals with autoimmune inner-ear disease ( AIED ) .
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方法取胎龄为4~7月的膜迷路制备人类胚胎耳蜗抗原(HumanembryocochlearAg,HEC-Ag)。
Methods The membranous labyrinth of human embryo ( 4 ~ 7 months ) was taken out . Human Embryo Cochlear Antigen ( HEC-Ag ) was prepared .
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MRI对膜迷路出血、炎症、小听神经瘤以及脑干小腔隙灶的显示比CT更具优势。
MRI was obviously superior to CT in detecting membranous labyrinthine hemorrhage , inflammation , small acoustic tumors and tiny lacunar infarction in brain stem .
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外耳道间断加压对豚鼠膜迷路积水及ANP表达的影响
Effects of intermittent overpressure on external ear on the endolymphatic hydrops and expression of ANP in internal ear of guinea pigs
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PFH5g/kg治疗给药20天,可显著降低膜迷路积水(HL)模型豚鼠听神经复合电位(CAP)阈值,缩短其潜伏期。
Meanwhile PFH ( 5g / kg , ig , for 20 days ) markedly decreased the threshold of compound action potential ( CAP ) and shorten their latency of guinea pigs injured by destruction of the endolymphatic sac .
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结论采用MSCT机薄层耳部扫描,VR能从平面和立体直观地显示耳部听小骨及内耳各细微结构,且可全面清晰立体观察膜迷路、前庭及与内听道内面、听神经的关系。
Conclusion MSCT ultra-thin section scan ( 0.5mm ) using volume rendering can display the fine structures of ears from the view of plane and three-dimension , as well as the relationship between membrane labyrinth , vestibule and facial / auditory nerve in the inner auditory canal entirely .
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迟发性膜迷路积水的内耳自身免疫因素研究
The clinical research of autoimmune factors correlating with delayed endolymphatic hydrops
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膜迷路破坏动物模型中水通道蛋白-1的表达及其意义
Expression of aquaporin-1 in a guinea pig model of labyrinth destruction
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耳蜗负和电位与动作电位比值与膜迷路积水
Ratio of Negative Summating Potential to Action Potential in Cochlea and Hydrolabyrinth
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新生小鼠膜迷路耳蜗外侧壁的组织培养
Tissue Culture of Lateral Cochlear Membrane Labyrinth in Neonatal Mouse
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用计算机图像分析技术研究膜迷路积水
Computer image analysis in the study of endolymphatic hydrops
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目的探讨实验性膜迷路积水前庭损害的机制。
Objective To explore the mechanism for the experimental vestibule damage in endolymphatic hydrops .
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目的豚鼠腹腔注射醛固酮建立膜迷路积水的动物模型。
Objective To develop endolymphatic hydrops in both ears of guinea pigs by aldosterone .
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实验性膜迷路积水耳蜗微循环的观察
Observation of Cochlear Microcirculation in Experimental Endolymphatic Hydrops
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但是加压素引起膜迷路积水的机制仍不十分清楚。
However , the mechanism of endolymphatic hydrops induced by vasopressin is still unclear .
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交感性迷路炎?&临床迟发性膜迷路积水的免疫因素研究
Sympathetic labyrinthitis ? & The research of immune factors correlating with clinical delayed endolymphatic hydrops
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此病的病理变化的实质是膜迷路积水。
The pathological entity of the disease is hydrocele of the membranous labyrinthine of the cochlea .
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膜迷路积水豚鼠的内、外淋巴液钾、钠离子浓度
Potassium and sodium ion concentration of the endolymph and perilymph in endolymphatic hydrops of the guinea pig
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氟桂利嗪、倍他司汀对膜迷路积水豚鼠蜗内电位及Ca~(2+)浓度的影响
Effect of flunarizine and betahistine on endocochlear potential and endolymphatic Ca 2 + concentration following experimental endolymphatic hydrops
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结论实验性膜迷路积水早期不影响前庭碳酸酐酶活性,提示实验性膜迷路积水早期对内淋巴液的产生无明显影响。
Conclusions It was suggested that the secretion of endolymphatic fluid was not affected at the early stage of the experimental endolymphatic hydrops .
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半规管开窗放置链霉素对正常和膜迷路积水耳的内耳功能和形态学影响
Effect of Streptomycin Placing in the Fenestra of Semicircular Canals on the Function and Morphology of the Normal and Hydropic Ears in Guinea Pigs
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结论:蛋白提取液中含1%SDS,去垢剂蛋白质比为5~6左右时对充分提取膜迷路蛋白较为合适。
Conclusion : 1 % SDS in solutions is relatively suitable for extracting membranous labyrinth proteins extensively while the ratio of detergent to protein is from 5 to 6 .
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结论:小鼠在出生时,其耳蜗膜迷路的大部分结构成份已经形成,出生后则需进一步的分化发育,至出生后2周时才完全发育成熟。
Conclusion : The major components of the membranous labyrinth has formed when the mouse is born . Postnatal development takes the form of the structures it takes 2 weeks after birth to achieve full development .
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方法以氯仿鼓室注射制造豚鼠膜迷路破坏的动物模型,运用免疫组化二步法在不同的时间点上检测膜迷路破坏豚鼠耳蜗及内淋巴囊中水通道蛋白-1的表达。
Methods Chloroform was injected into the tympanum to establish the animal model of labyrinth destruction in guinea pigs , and two-step immunohistochemical method was used to examine the expression of AQP-1 in the cochlea and endolymphatic sac at different time points .
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结论(1)共同腔畸形极重度聋患者不仅前庭、外半规管和耳蜗的骨性结构形态发生了变化,而且腔内耳蜗中阶与前庭的球囊、椭圆囊的膜迷路结构形态也发生了变化;
Conclusions ( 1 ) In common cavity malformation , in addition to the abnormal bony labyrinth such as the cochlea , vestibule and lateral semicircular canal , the inner ear perceptive organ such as the saccule , utricle and scala media were also abnormal .