肝郁脾虚

肝郁脾虚证大鼠TXB2、6-Keto-PGF（1α）含量的观察研究

Observation of TXB_2 、 6-Keto-PGF_ ( 1 α) on Rats with Liver Depression and Spleen Deficiency

UC中医证候分布规律：患者中医证候以肝郁脾虚证和大肠湿热证为最多，各占36.67%和21.11%。

UC Syndrome Distribution : TCM syndrome in patients with colorectal liver depression and spleen deficiency and damp as the most , 36.67 % and 21.11 % each .

肝郁脾虚证患者口服加味逍遥散后阿魏酸的血药浓度HPLC测定法

HPLC Determination of Concentration of Ferulic Acid in Blood of Patients with Liver Depression and Spleen Deficiency

ALT、AST在湿热中阻型及肝郁脾虚型高於其他三型且有显著性意义（P＜0.01）；

The ALT and AST in dampness-heat accumulation and liver-depression and spleen asthenia are remarkable higher than the other three types .

肝郁脾虚因素促进DEN诱发大鼠实验性肝癌的研究

Research on the Impact of Liver-stagnation and Spleen-deficiency on Experimental Hepatocarcinoma Induced by DEN in Rats

肝郁脾虚因素刺激对DEN诱发肝癌大鼠免疫功能的影响

Influence of the Factors of Liver Depression and Spleen Deficiency on Immunological Function in the Rats with Hepatocarcinoma Induced by Diethylnitrosamine

结论：肝郁脾虚因素可促进DEN诱发大鼠实验性肝癌的发生发展。

Conclusion : The factor of liver-stagnation and spleen-deficiency could promote the development of experimental hepatocarcinoma induced by DEN in rats .

目的探讨肝郁脾虚证、脾虚证、肝郁证与神经肽CRF之间的相关性。

Objective To study the correlativity between liver-depression and spleen-deficiency syndrome , spleen-deficiency syndrome , liver-depression syndrome and corticotrophin releasing factor ( CRF ) .

中医证候中肝郁脾虚证患情志障碍的发病率为100%，中医证候与焦虑抑郁的发生有明显相关性（P0.05）。

In stagnation and spleen deficiency syndromes suffer from emotional disorders certificate incidence rate was 100 % different syndromes of depression and anxiety difference in the incidence of significant correlation ( P < 0.05 ) .

血瘀、热郁湿阻型、肝肾亏虚型3型血清HA值依次升高，与肝郁脾虚型比较均有显著差异；

And in turn both liver and kidney deficiency type > heat-stagnancy and damp block type > Qi-stagnancy and blood stasis type , the three types compared with liver-Qi stagnancy and spleen-deficiency type was significant difference ;

目的探讨中医辨证为肝郁气滞型与肝郁脾虚型抑郁症患者在HAMD抑郁量表结构因素方面的差异。

Objective To discuss the different factorial structure of HAMD Scale between the patients of liver Qi stagnation syndrome and liver stagnation and spleen deficiency syndrome .

远期疗效方面，总体病例及肝郁脾虚组病例治疗组各主要症状好转仍较明显，对比治疗前差异有显著性意义（P0.05）。

The long term therapeutic effects , all of the general cases and liver stagnation and spleen deficiency cases , the treatment group with patients with the main symptoms is better then before treatment , differences are significant ( P0.05 ) .

逍遥散对肝郁脾虚证模型大鼠海马和杏仁核AMPA受体亚基基因表达的影响

Influence of Xiaoyao Powder on subunit gene expression of AMPA acceptor in amygdala and hippocampus in rat model of liver-stagnation and spleen-deficiency syndrome

舒肝健脾法对肝郁脾虚型溃疡性结肠炎患者肠粘膜ICAM-1、VCAM-1表达的影响

The Difference Expressions between ICAM-1 and VCAM-1 of Colonic Tissues of Patients with UC of the Liver Depressed and Spleen Weakness Type , Who is Treated by the Method of Shugan Jianpi

肝肾阴虚、瘀血阻络型组C3b降低（P＜0.01），而肝郁脾虚组无明显变化（P＞0.05）；

The RBC C3b receptor rosette - forming rate were decrease in Blood - stasis and Yin deficiency of liver and kidney ( P < 0.01 ), there were no chandes in Depression of liver due to spleen deficiency ( P > 0.05 );

目的探讨痛泻二草方对肝郁脾虚型溃疡性结肠炎（UC）模型大鼠肠黏膜屏障损伤的影响。

Objective To study effects of Tongxie Ercao Fang ( TXECF ) on barrier loss of intestinal mucosa in rats with ulcerative colitis ( UC ) of stagnation of liver-qi and deficiency of the spleen .

中医证型与病程差异有统计学意义（P0.05），病程较长的患者中痰湿内蕴型、痰瘀互结型较肝郁气滞型、肝郁脾虚型多见。

The distribution of TCM syndrome types and course of disease have obvious correlation ( P0.05 ): Patients with long duration have damp-heat type and phlegm stagnation type more common than liver depression and qi stagnation type 、 liver depression and spleen weak type . 7 .

目的观察肝郁脾虚因素对S180荷瘤小鼠肿瘤生长和T细胞免疫功能的影响。

Objective To observe the influence of the factor of liver depression and spleen deficiency ( LDSD ) on the growth of tumour and the immune function of T cells in S180 tumor bearing mice .

[目的]探讨肝郁脾虚型肠易激综合征（IBS）与5-羟色胺转运体（SERT）基因多态性的关系。

[ Objective ] To investigate the relationship between irritable bowel syndrome ( IBS ) of hepatic stagnation and spleen deficiency type and serotonin transporter ( SERT ) gene polymorphism .

平调肝脾法在治疗IBS-D肝郁脾虚型患者方面具有良好的临床疗效，其突出疗效与其组方严谨、切中病机有关。

This method has a good clinical efficacy , its outstanding efficacy is related to its rigorous structure and stringent hit the pathogenesis .

结论：脾气虚证患者PK特征表现为吸收速度加快，分布和排泄减慢；肝郁脾虚证患者PK特征表现为吸收、分布和排泄均减慢；

Conclusion : The PK analysis of FA in the patients with syndrome of deficiency of spleen qi shows that the absorption rate is accelerated , and both the distribution and elimination rates are slowed down .

前言：目的观察中药疏肝饮煎剂对肝郁脾虚型肠易激综合征模型大鼠的治疗作用及对胃动素（MOT）、胆囊收缩素（CCK）的影响。

Objective To study the effects of " Shugan Beverage " on motilin ( MOT ) and cholecystostomy ( CCK ) in rats of diarrhea-predominant irritable bowel syndrome ( IBS ) of liver depression and spleen deficiency .

的项目。结果：①热郁湿阻型、肝肾亏虚型SB、TBA均值均明显高于肝郁脾虚型，分别有显著差异；

Re sult : ① Among the four types , heat stagnancy and damp block type and both liver and kidney deficiency types SB 、 TBA level were markedly higher than liver-Qi stagnancy and spleen-deficiency types , the difference between groups was significant ;

HBeAg/抗HBe转换率分别为肝胆湿热34.4%、肝郁脾虚15.6%，P<0.05。结论：慢性乙型肝炎不同的中医辩证分型与拉米夫丁抗病毒效应有一定的相关性。

HBeAg anti-HBe seroconversion was achieved 34.4 % and 15.6 % P < 0.05 . Conclusion : There was certain correlation between different diagnostication of Traditional Chinese Medicine and lamivudine in the treatments of chronic hepatitis B.

结果：1.180例UC患者中医证型分布情况依次为：湿热内蕴证脾胃虚弱证肝郁脾虚证气滞血瘀证脾肾阳虚证阴血亏虚证，其中以湿热内蕴证为主，占全部患者的28%。

Results : 1.180 cases of UC patients the distribution of TCM were : damp card weak stomach card Liver Spleen deficiency qi stagnation card spleen deficiency syndrome Yin and Blood deficiency syndrome , which damp cards , accounting for 28 % of all patients . 2 .

结论：妊娠可使慢性乙肝肝郁脾虚型患者血清IL-12、IFN-γ浓度升高，在晚孕期表现更为明显。

Conclusion : Pregnancy may affect the TH 1 related cytokines ( IL 12 , IFN Y ) in patients with chronic hepatitis B of the liver qi stagnancy and spleen deficiency type , and the effect is more obvious in patients during late stages of pregnancy .

IBS中医病机常责之为肝郁脾虚，不同病变阶段的临床表现均不相同，但基本病机总离不开肝郁脾虚，肝郁脾虚贯穿于疾病发展的始终。

Traditional Chinese medicine pathogenesis of IBS often responsible for the stagnation and spleen deficiency , different pathological stages of clinical manifestations vary , but the basic pathogenesis is always the stagnation and spleen deficiency , stagnation and spleen deficiency throughout the development of the disease is always .

NAFLD组所有患者按中医辨证分型标准分为肝郁脾虚证、湿热内蕴证、痰瘀互结证、肝肾亏虚证4型。

Within the NAFLD Group , according to the syndrome differentiation typing theory of Traditional Chinese Medicine , the subjects were sub-grouped as Liver Stasis and Spleen Deficiency Syndrome , Damp-hot Internal Holding Syndrome , Sputum Stagnation Syndrome , and Liver-Kidney Deficiency Syndrome .

近年来对IBS-D发病机制的研究逐渐深入到了分子水平，但还比较片面。中医学认为肝郁脾虚是其基本病机，肝郁脾虚证是其最主要的证型。

Recently , some molecular mechanisms are studied . Liver depression and spleen deficiency is the basic pathogenesis of IBS-D in traditional Chinese medicine , liver depression and spleen deficiency syndrome is the main syndrome .

至于本虚，台湾高雄地区的NAFLD患者则主要表现为脾虚。4.3NAFLD呈慢性过程，发病初期多表现为肝郁脾虚、湿热内蕴、脾虚湿蕴、肝郁气滞等。

And root deficiency is mainly manifested as spleen deficiency . 4.3 The course of NAFLD is long . In the beginning stage , most patients are manifested as liver depression and spleen deficiency , accumulation of damp-heat , spleen-deficiency and retention of dampness , stagnation of liver-qi .