羧基端

目的：制备人纤维连接蛋白（fibronectin，FN）羧基端细胞结合域的单克隆抗体，并以该抗体检测心脏瓣膜基质蛋白中FN蛋白的表达情况。

Objective : To prepare the monoclonal antibodies against carboxy-terminal cell-binding domain of fibronectin ( FN ), and to use the product for detection of FN protein in heart valve matrix .

另一方面，促进释放血管形成抑制因子：血管他汀裂解纤溶酶原、内因子（MMP裂解产生的Ⅲ、V、X型胶原基底膜的羧基端片断），抑制血管生成。

On the other hand , to promote the release of the angiogenesis inhibitor : Vascular statins cracking plasminogen intrinsic factor ( the MMP cleavage III , V basement membrane type X collagen carboxy-terminal fragment ), inhibition of angiogenesis .

猪圆环病毒Cap蛋白羧基端特异性单克隆抗体的制备

Preparation oF Special Monoclonal Antibody of Cap Protein Carboxyl Terminus of Porcine Circovirus

Toll样受体2胞外域及其氨基端和羧基端片段的克隆与序列分析

Cloning and sequencing of extracellular domain and N-Terminal and C-Terminal fragments of Toll-like receptor 2

抑制性消减杂交构建乙型肝炎病毒X蛋白羧基端缺失40个氨基酸cDNA文库

Construction of cDNA library of hepatitis B virus with X protein C-terminally truncated 40 amino acids by suppression subtractive hybridization method

每一个多肽链从氨基端到羧基端由A、B、C三个重复片段组成，A区为高度变异区，诱导机体产生型特异性保护抗体的抗原决定簇位于该区。

Each polypeptide may consist of up to three repeat regions A-C from N-terminus to C-terminus . A-repeat region is hypervariable , type-specific and protective epitopes are located in it .

EB病毒核抗原1羧基端原核表达产物的纯化方法

Purification of carboxyl - terminal domain of epstein-barr virus nuclear antigen 1 expressed in E. coli

EB病毒LMP1羧基端胞浆区介导端粒酶活化

Telomerase activation is medicated by the carboxyl terminus region of Epstein-Barr virus LMP1

大肠杆菌中表达的木聚糖酶B在羧基端上带有6×His标签蛋白质，用一步Ni-NTA亲和柱层析可使酶的纯度达90%以上。论科技语篇文本的空间信息对接

The translated protein was soluble with xylanase activity . On spatial information in matching the original with the translated text

EB病毒核抗原1羧基端的原核表达、纯化及其免疫学特性

Prokaryotic Expression , Purification and Immunological Analysis of Carboxyl - Terminal Domain of Epstein-Barr Virus Nuclear Antigen 1

游泳运动可以使血清骨钙素、B型血清碱性磷酸酶和Ⅰ型前胶原羧基端前肽等骨形成生化标志物显著升高，而骨吸收生化标志物I型胶原交联N末端肽显著下降。

Swimming could promote the biochemical markers such as serum osteocalcin , type B serum alkaline phosphatase and carboxyterminal propeptide of type ⅰ precollagen , and reduce type ⅰ collagen cross-linked N telopeptide .

不同地区幽门螺杆菌cagA基因羧基端可变区及其蛋白序列差异分析

Diversity of cagA gene 3 ' terminal variable region and its corresponding protein in Helicobacter pylori

融合在外源蛋白羧基端的Tat蛋白转导结构域的跨膜递送作用研究

The Study of the Transmembrane Activity of the PTD of Tat Protein Fused at the Carboxyl-terminus of Heterologous Protein

我们鉴定了SCAN-（C2H2）X基因会在其羧基端截除锌指结构域。

It is firstly characterized for the SCAN - ( C2H2 ) X genes to truncate the zinc finger domains at the carboxyl terminus .

GSTPull-down实验表明，此融合蛋白可与乙酰肝素酶羧基端大亚基蛋白结合。

Results : GST pull down assay presented that the expressed fusion protein could combine with the C-terminal subunit protein of heparanase .

泛素羧基端水解酶UCH家族水解反应动力学研究

Study on the Activity and Kinetics of Ubiquitin C-terminal Hydrolase

HBx羧基端缺失40个氨基酸相关上调/下调基因的筛选和初步功能研究

Preliminary Study and Screening of the Up - and Down-regulation Genes Correlated with HBx COOH-terminally Deleted 40 Amino Acids

通过IR测定，对丁二酰化壳聚糖和顺丁烯二酰化壳聚糖观察到含自由羧基端的线形取代，对邻苯二甲酰化壳聚糖，在反应程度较高时还出现环状取代。

After IR determination , a linear substituent with a free carboxyl group can be observed for butanedioic chitosan and maleoyl chitosan , nevertheless a circle-like substituent was found for phthaloyl chitosan at high degree of reaction .

目的研究乙型肝炎病毒（HBV）C蛋白羧基端短小的干扰RNA（siRNA）对HBV超螺旋双链闭环DNA（cccDNA）水平的影响。

Objective To study the effect of hepatitis B virus ( HBV ) C protein C-terminal small interference RNA ( siRNA ) on reduction of HBV covalently closed circular DNA ( cccDNA ) level .

酪氨酸蛋白激酶（ProteinTyrosineKinase，PTK）是存在细胞膜或细胞浆中的蛋白激酶，它具有典型的羧基端催化区，当被激活后可以将其底物以及自身的酪氨酸残基磷酸化。

Protein Tyrosine Kinase ( PTK ) is a kind of kinase which exists in cellular membrane or cytoplasm . Having typical carboxyl-terminal , PTK can phosphorylate downstream molecules and also phosphorylate itself .

猪圆环病毒Ⅱ（PCV2）衣壳蛋白羧基端基因在T4噬菌体表面的展示

Display of the Carboxyl Terminus Gene Fragment of Porcine circovirus Type 2 ( PCV2 ) Capsid Protein on the T4 Bacteriophage Surface

首次证明了在RAP羧基端108个氨基酸多肽链上至少存在一个病理性抗原决定簇。人生长激素分子的抗原决定簇研究

CONCLUSIONS We conclude that at least one nephrogenic epitope is presented within the COOH teminal 108 amino acids polypeptide of RAP molecules . STUDY OF ANTIGENIC DETERMINANTS OF hGH

方法：采用RT－PCR和分子克隆技术构建PrM－E基因片段，包括编码PrM的信号肽序列、完整的PrM蛋白和去除羧基端跨膜疏水区部分氨基酸的97.8%E蛋白的基因片段。

Methods : The PrM E gene , containing the PrM signal sequence , whole PrM and 97.8 % E , was constructed by RT PCR and molecular cloning technologies .

方法：构建含有APP羧基端106个氨基酸的融合表达质粒，用酵母双杂交系统筛选人胎脑cDNA文库。

Methods : A fusing expressed plasmid , which contains the 106 amino acids at the carboxyl terminal of APP , was constructed . Screening against human embryo brain cDNA library by two hybrid system was performed .

Nogo蛋白的羧基端与连接蛋白26相互作用及在小鼠内耳中的表达

Functional interaction of the C-terminal of Nogo protein with connexin 26 and the expression of Nogo 's mRNA in the murine inner ear

目的测定高血压病（EH）患者血清Ⅰ型前胶原羧基端肽（PIP）的水平，并探讨其与左心室肥大的关系。

Objective To study relationship between serum concentration of precollagen type I carboxy terminal peptide ( PIP ) and left ventricular hypertrophy ( LVH ) in patients with essential hypertension ( EH ) .

小鼠Ras激酶抑制剂（KSR）基因氨基端和羧基端真核表达载体的构建及其在293T细胞中的表达

Construction of eukaryotic expression vectors of carboxyl terminus and amino terminus of kinase suppressor of Ras ( KSR ) and their expression in 293T cell line

HBx羧基端的缺失可能改变了野生型HBx在控制细胞增殖、分化、凋亡方面的作用，从而在HBV相关HCC中发挥重要作用。

Deletions in the HBx-COOH-terminal alter a key role that the wild-type HBx plays in controlling cell proliferation , differentiation , and apoptosis , they may play a critical role in HBV-associated HCC .

HIF-1α蛋白质的氨基酸链的羧基端接受到核转位信号后即从胞质转位至胞核，与HIF-1β结合形成有活性的二聚体。

A nuclear localization signal at the C-terminal end of HIF-1 α allows its transport from the cytoplasm to the nucleus , where it forms an active HIF-1 complex by binding to HIF-1 β .

Heymann肾炎致病原受体相关蛋白羧基端病理性抗原决定簇的定位

Identification of a pathogenic epitope on COOH terminal of the 44 KD receptor associated protein ( rap ) of Heymann nephritis antigenic complex