美罗培南

其次是多黏菌素E和美罗培南，敏感率分别>88.0%和84.0%；

The susceptibility rate to polymyxin E and meropenem were more than 88.0 % and 84.0 % , respectively .

对亚胺培南、美罗培南、多黏菌素B、多黏菌素E的耐药性较低，分别为22.4%、22.4%、0%、10.2%。

The resistant rates of imipenem , meropenem , polymycin B and polymycin E were 22.4 % , 22.4 % , 0 % and 10.2 % separately .

目的：评价美罗培南（MEM）治疗重症细菌性感染的疗效和安全性。

To evaluate the efficacy and safety of meropenem ( MEM ) in the treatment of patients with serious bacterial infections .

结论美罗培南对革兰阴性杆菌有很强的抗菌活性，其抗菌活性要强于亚胺培南，是目前治疗肠杆菌科细菌特别是产ESBLs、AmpC酶细菌感染的危重患者的最理想用药。

Conclusions Meropenem has better antibacterial activity against Gram-negative bacterial than imipenem . It is the reasonable drug to cure the serious patient with Gram-negative bacterial carrying ESBLs , AmpC enzyme and metallo-enzyme currently .

对筛选出来的32株对亚胺培南和美罗培南不同耐药表型的Pa，采用实时荧光定量PCR法，检测三种外排泵基因（mexA、mexD、mexF）的表达量。

For 32 strains with different resistant phenotypes to imipenem and meropenem , the mRNA expression levels of three efflux pump genes ( mexA 、 mexD 、 mexF ) were quantified by real time fluorescent quantitative PCR .

国产美罗培南治疗急性细菌性感染的临床试验

Clinical trial of domestic meropenem in treatment of acute bacterial infections

美罗培南治疗细菌感染的多中心临床研究

Multi Center Clinical Study on Treatment of Bacterial Infections with Meropenem

1β-甲基碳青霉烯类抗生素美罗培南合成进展

Progress in synthesis of 1 β - methyl carbapenem antibiotic meropenem

美罗培南治疗呼吸系统细菌性感染的随机对照临床研究

A Randomized Controlled Clinical Study on Meropenem in Respiratory Bacterial Infections

美罗培南治疗重症社区获得性肺炎临床疗效观察

Efficacy Evaluation of Meropenem in Patients with Serious Community-acquired Pneumonia

美罗培南在血液系统疾病合并感染时的应用

Application of meropenem for the patients with blood diseases complicated with infections

美罗培南和亚胺培南-西司他丁对100株革兰阴性杆菌体外抗菌活性比较

Comparative in vitro antimicrobial activity of meropenem and imipenem-cilastatin against 100 gram-negative bacilli

美罗培南在烧伤患者的药代动力学研究

Pharmacokinetics of meropenem in the patients with burn injury

美罗培南治疗老年人医院获得性肺部感染的临床评价

Clinical efficacy of meropenem in older nosocomial infection patients

单次静脉美罗培南在健康人体的药代动力学

Pharmacokinetics of meropenem single dose intravenous in healthy volunteers

国产美罗培南对重症革兰阴性菌感染的临床评价与敏感性分析

Clinical Evaluation and Sensitivity Analysis of Meropenem on Patients with Severe Gram-negative Bacteria

美罗培南对革兰阴性杆菌体外抗菌活性的分析

In Vitro Antibacterial Activity of Meropenem in Gram-negative bacilli

美罗培南在家兔胆汁中的药物浓度-时间分布的实验研究

Distribution and Concentration of Meropenem in Rabbit Bile

美罗培南对lasR/rhlR基因缺陷型铜绿假单胞菌早期生物膜的作用

Effect of Meropenem on Biofilms of Pseudomonas aeruginosa lasR / rhlR Mutations in vitro

美罗培南的临床评价

Synthesis of pemetrexed Clinical evaluation of meropenem Beauty

国产美罗培南治疗多重耐药菌感染的临床观察

Domestic Meropenem in Treatment of Infection for Multi-drug Resistant Bacteria : A Clinical Study

美罗培南治疗儿童肿瘤疾病合并感染的疗效评价

Meropenem in Treating Blood Tumor Combined with Infection in Children : Effect and Analysis

目的观察美罗培南治疗中、重度细菌感染的有效性。

Objective To evaluate the efficacy of meropenem in moderate to severe bacterial infection .

美罗培南治疗医院感染的临床研究

Meropenem in Treatment of Hospital Acquired Infection

碳青霉烯类如亚胺培南及美罗培南是肺炎克雷伯菌感染的首选用药。

Carbapenems such as imipenem and meropenem were the first choice to Klebsiella pneumoniae infection .

美罗培南、亚胺培南治疗成人急性粒细胞缺乏症的疗效观察

Meropenem and Imipenem Used to Treat Adult Acute Neutropenia Syndrome ( AANS ): Their Clinical Efficiency

美罗培南治疗急性白血病粒细胞减少期并发肺部感染25例

Efficacy of meropenem in treating 25 patients with secondary pulmonary infection of acute leukemia in granulocytopenia phase

结果联合外排泵抑制剂后，亚胺培南、美罗培南耐药率下降均不明显，没有统计学意义。

Results The resistance rate of imipenem and meropenem descended gently after combined with efflux pump inhibitors .

目的探讨美罗培南在治疗机械通气新生儿下呼吸道细菌感染中的疗效。

AbstractObjectiveTo explore the effect of meropenem on lower respiratory infection in newborn infants with mechanical ventilation .

结论美罗培南在胆汁中能达到较高的有效杀菌浓度，可作为预防和治疗胆道感染的较佳的药物。

Conclusion Meropenem could achieve adequate bile concentration for the treatment of biliary tract infection due to susceptible bacteria .