细胞膜离子通道

目的：研究溶血磷脂酸（LPA）对心肌细胞膜离子通道的作用及机制。

Objective : To study the effect of lysophosphatidic acid and their mechanisms .

高糖对体外培养的视网膜Müller细胞膜离子通道的影响

Effects of high concentration glucose on ion channel of retinal M ü ller cells cultured in vitro

目的：分别观察黄体酮（Progesterone）和5-羟色胺（5-HT）对豚鼠结肠平滑肌肌条和细胞膜离子通道电流和膜电流的作用。

Objective : To investigate the effects of progesterone and 5-HT on spontaneous contraction of muscle strips and the ionic channels currents of single guinea pig proximate colon .

心肌细胞膜离子通道活性的研究及某些应用

A study on the activities of ionic channels and some applications

细胞膜离子通道的一个非线性动力学模型

A Nonlinear Dynamical Model of Ion Channel in Cell Membrane

细胞膜离子通道内离子谐振分析

Analysis of ionic resonance in the ionic channel of the cell membrane

一类细胞膜离子通道模型的分岔及混沌研究

Study on Bifurcation and Chaos of an Ion Channel Model in Cell Membrane

细胞膜离子通道及其检测技术的研究进展

Advance of the ion channels on the cell membrane and their testing technique

本文探讨了基本上属于两态的细胞膜离子通道事件的自动分析方法。

From the two-state events of ion-channel we have approached to a way of automatic analysis technique .

目的探讨萎缩比目鱼肌高频强直收缩疲劳性增加涉及细胞膜离子通道的可能机理。

Objective To elucidate the underlying mechanisms of the high fatigability in mouse atrophic soleus during high-frequency tetanic contraction .

心肌细胞膜离子通道在膜电位的形成与维持，心脏功能调节以及药物作用方面都有十分重要的生理意义。

Cardiac membrane ion channels are very important for maintains of membrane potential , modulation of heart function and also for drug actions .

细胞膜离子通道的正常活动是血管平滑肌兴奋舒缩过程的关键，也是维持细胞的兴奋性与膜稳定性的保证。其中，钙通道与钾通道的作用至为重要。

Ion channels in cell membrane , especial calcium channels and potassium channels , play an important role in the regulation of vascular tone .

现代科学证明，不少疾病都与生物细胞膜离子通道病变有关，表现为生物模型中相关参数的异常变化，这类疾病可归类为离子通道疾病。

It is reported that many diseases that are often termed as ion channel disease are related with the aberrance of cell trans-membrane ion channels .

膜电位的变化必然会改变细胞膜离子通道状态，导致细胞内离子浓度变化。

The changes of cell membrane potential certainly alter the states of ion channel in cellular membrane , which induce the changes of ionic concentration .

心功能的降低与心肌细胞膜离子通道、钠钙交换蛋白及肌质网钙泵功能的下降以及心肌间质纤维化等有关。

Besides the myocardial fibrosis , the decreased cardiac function is also related to the functions of membrane channel protein , Sarco endo reticulum calcium ATPase .

背景与目的随着膜片钳技术和分子生物学技术的发展，及其在肿瘤细胞膜离子通道研究中的应用，肿瘤细胞膜离子通道已逐渐成为肿瘤基础研究的热点。

Background and objective With the development of patch clamp and molecular biology technique , and the application of them in the investigation of tumor cellular membrane ion channnel , the ion channel is becoming the hot spot of the tumor base research gradually .

细胞膜K离子通道的动力学模型

Kinetic model of K channel

本文提出了一种隐马尔可夫模型（HMM）和径向基函数（RBF）神经网络相结合的混合模型，用于白噪声背景下细胞膜离子单通道电流的统计重构。

A hybrid model of HMM and RBF neural network is presented to reconstruct the ionic single channel current under white background noise .

正常人与囊性纤维化病人汗腺细胞膜单离子通道对Forskolin的反应

Single Ion Channel Responses of Sweat Gland Cell Membrane from Normal Individuals and Patients with Cystic Fibrosis to Forskolin

利用膜片钳放大器系统对细胞膜上离子通道跨膜电流变化极其灵敏的特点，研究并构建一种新型的膜片电极支撑BLMs核酸传感器，对SEB基因进行快速、灵敏和特异的检测。

The biosensor was fabricated by utilizing patch-clamp pipette technology , which characterized in sensitive changes of ionic current though physiological cellular membranes .

人肝癌HCC-9204细胞膜钾离子通道特性的研究

A study on the characteristics of the potassium channel in human hepatocyte carcinoma cell line HCC-9204

方法利用膜片钳放大器系统对细胞膜上离子通道跨膜电流变化极其灵敏的特点，构建一种新型BLMs。

Methods One kind of novel BLMs was fabricated by using patch-clamp pipette technology characterized by sensitive changes of ionic current through cellular membranes , and confirmed by Gramicidin method .

结论豚鼠耳蜗传出神经递质ACh通过兴奋N受体，开放OHC的细胞膜钙离子通道，使细胞外Ca2+内流外毛细胞内；[Ca2+]i增加需要细胞外液中钙离子存在。

Conclusion The data indicate that ACh , the neurotransmitter of efferent auditory nerve in cochlea , activates the nicotinic receptor to open the calcium channel in OHC membrane and increase [ Ca 2 + ] I of OHCs , which is extracellular Ca 2 + - dependent .

滤波和有色背景噪声影响下细胞膜离子单通道信号的自适应恢复算法研究

Adaptive Restoration of Single Ion Channel Signal under Filtering and Colored Background Noise

细胞膜离子单通道信号的统计重构算法研究

Study of statistical algorithms for reconstructing the single cell membrane ion channel signals

细胞膜离子单通道信号是皮安级的随机电流，膜片钳技术可以记录这些信号。

The signal of single ion channel is stochastic ionic currents on the order of1pA , which can be recorded by means of patch clamp technique .

应用膜片钳技术可以证实细胞膜上离子通道的存在并能对其电生理特性、分子结构、药物作用机制等进行深入的研究。

Application of the patch-clamp technique can demonstrate the existences of ion channels and provide valuable information for ion channels , including their electrophysiological properties , molecular structures and the mechanism of drug action .

目的：研究血管紧张素Ⅱ（AngⅡ）对乳鼠缰核（Hb）细胞膜上钾离子通道活动的影响，以了解Hb内AngⅡ的作用机制。

Aim : To study the effects of Ang ⅱ on the I K channel in isolated rat habenula ( Hb ) nucleus neurons .

结论人肝癌HCC-9204细胞膜存在钾离子通道，其主要类型可能是电压依赖性钾通道。

Conclusion Voltage-gated K ~ + channel maybe one of the important types in human hepatocyte carcinoma cell line HCC-9204 .

庆大霉素对前庭毛细胞膜的钙离子通道可能有阻滞作用。

It is suggested that gentamicin can block the calcium channels of VHCs .