纤溶酶原激活因子

纤溶酶原激活因子及其抑制因子与卵巢癌的浸润转移

The Study on Relationship between the Expression of Plasminogen Activator , Plasminogen Activator Inhibitors and Invasion and Metastasis in Ovarian Carcinoma

目的：探讨尿激酶型纤溶酶原激活因子（uPA）对于奥硝唑所致的雄性不育大鼠生育力的影响。

Objective : To investigate the effects of urokinase-type plasminogen activator ( uPA ) on the reproductive function of the male rats with ornidazole-induced infertility .

纤溶酶原激活因子（PA）包括尿激酶型（uPA）及组织型（tPA），在诱发细胞外基质蛋白水解中起重要作用。

Plasminogen activators include urokinase type ( uPA ) and tissue type ( tPA ) plasminogen activator , which play a critical role in promoting proteolysis of extracellular matrix .

测定了rETIa对胰蛋白酶、胰凝乳蛋白酶、组织型纤溶酶原激活因子缺失突变体（NTA）的抑制活性。

Inhibitory assay showed that rETIa had inhibitory activities against trypsin , chymotrypsin and tPA deletion variant NTA .

目的观察米非司酮对体外培养大鼠蜕膜组织的作用以及对蜕膜组织分泌纤溶酶原激活因子（PA）和血小板激活因子（PAF）的影响，探讨其抗早孕的作用机理。

Objective : To observe the effect of mifepristone on the production of PA ( plasminogen activator ) and PAF ( platelet activating factor ) in the rat 's deciduas to probe into the antifertility mechanism .

目前对CP所致精液延迟液化机制的研究主要集中在蛋白水解酶系、纤溶酶原激活因子系统和微量元素锌缺乏以及pH值改变等方面。

There seems to be a strong association between CP and semen delayed liquefaction . Researches on the mechanism of semen delayed liquefaction resulting from CP mainly focus on the proteolytic ferment , plasminogen activator , prostate acid phosphatase , tissue factor , lack of zinc , and pH.

小鼠生殖周期中纤溶酶原激活因子及抑制因子的表达

Expressions of plasminogen activators and inhibitors in mice during reproductive cycle

福斯科林对大鼠排卵的作用及卵巢纤溶酶原激活因子活性影响

The effect of forskolin on ovulation and ovarian plasminogen activator activity in rats

猕猴精浆纤溶酶原激活因子的来源及在精子获能中的作用

Source of plasminogen activator in rhesus monkey semen and its possible role in sperm capacitation

组织型纤溶酶原激活因子基因真核表达质粒的构建及其体外表达研究

Construction and in vitro Expression of Human Tissue-type Plasminogen Activator Gene Recombinant Eukaryotic Expression Vector

弱精症男子与正常人精子膜尿激酶型纤溶酶原激活因子含量的研究

Comparative quantification of the membrane-associated urokinase plasminogen activator ( uPA ) on the ejaculated spermatozoa between sterile patients with asthenospermia and healthy fertile Men

米非司酮对早孕大鼠蜕膜、黄体分泌组织型纤溶酶原激活因子及蜕膜组织学的影响

Effects of Mifepristone on the Production of tPA in Cultured Rat Decidua and Corpus Luteum of Early Pregnancy and on the Morphology of Decidua

以上结果说明，小鼠胚胎着床过程中胰蛋白酶及纤溶酶原激活因子等水解蛋白酶的活性起着重要作用。

These results suggested that proteolytic activities were involved in implantation , some proteinases such as trypsin and plasminogen activator had important functions during trophoblast invasion .

体外转染验证其可正确指导合成及分泌组织型纤溶酶原激活因子，表现出显著纤溶活性，为后续实验奠定了实验基础。

And verify that the vector can correctly guide the synthesis and secretion of tissue-type plasminogen activator , showing a significant biological activity in vitro transfection .

结论：组织型纤溶酶原激活因子可抑制血小板在材料表面的黏附，具有特异的溶栓作用，可以用于防治生物材料的细菌黏附。

CONCLUSION : Due to the specific thrombolysis action , t-PA can inhibit the adhesion of platelets on Dacron and PTEF material , and prevent the bacterial adhesion on biomaterial .

纤溶酶原激活因子与猕猴精子运动力的关系及其在附睾和附性腺中的表达调节

Possible Involvement of Plasminogen Activator in the Acquirement of Sperm Progressive Motility and the Regulation of PA and PAI-1 mRNA Expressions in Epididymis , Prostate and Seminal Vesical in Rhesus Monkey

目的：探讨脑膜瘤微坏死与纤溶酶原激活抑制因子-1（PAI-1）和预后的关系。

Objective : To investigate the association of micronecrosis with plasminogen acti-vator inhibitor-1 ( PAI-1 ) and its prognosis in meningiomas .

纤溶酶原激活抑制因子1基因在人脑星形细胞瘤中的表达及意义

Expression and its significance of plasminogen activator inhibitor 1 gene in human astrocytoma

目的：探讨中国人群中血浆纤溶酶原激活物抑制因子-1（PAI-1）基因变异和2型糖尿病（DM）、高血压病、冠心病的关系。

Objective : To explore the relationship between polymorphism of PAI-1 gene and type 2 diabetes mellitus ( DM ), hypertension , and , coronary heart disease .

目的：探讨糖尿病患者血清肿瘤坏死因子-α（TNF-α）、纤溶酶原激活物抑制因子-1（PAI-1）水平及其血液流变特性与糖尿病微血管病变的相关性。

Objective : To explore the roles of tumor necrosis factor - α ( TNF - α) , plasminogen activator inhibitor type 1 ( PAI - 1 ) and hemorheology in diabetic microangiopathy .

目的研究SiO2对人肺泡Ⅱ型上皮细胞（A549）中纤溶酶原激活物抑制因子1（PAI1）及激活蛋白1（AP1）表达的影响，探讨SiO2致肺纤维化的发病机制。

Objective To investigate the mechanism of silicosis by observing the effects of silica on the expression of plasminogen activator inhibitor-1 ( PAI-1 ) and activator protein-1 ( AP-1 ) in human alveolar epithelial cells type ⅱ( A549 ) .

少数2型糖尿病和肥胖青少年的纤溶酶原激活剂抑制因子-1和组织纤溶酶原激活剂

Plasminogen activator inhibitor-1 and tissue-plasminogen activator in minority adolescents with type 2 diabetes and obesity

二氧化硅对人肺泡Ⅱ型上皮细胞纤溶酶原激活物抑制因子-1和激活蛋白-1表达的影响

Effects of silica on the expression of plasminogen activator inhibitor-1 and activator protein-1 in human alveolar epithelial cells type ⅱ

本文主要阐述了脂肪组织分泌因子白细胞介素-6、肿瘤坏死因子-α、纤溶酶原激活物抑制因子-1、血管紧张素Ⅱ和抵抗素的功能特性及其对脂肪形成的影响。

In this paper , the functional characters and effects of some factors secreted from adipose tissue on adipogenesis , such as interleukin-6 , tumor necrosis factor-a , plasminogen activator inhibitor-1 , angiotensin ⅱ and resistin , are elucidated .

纤溶酶原激活剂及其抑制因子1在大鼠脊髓急性损伤时的表达

Expression of Tissue-type Plasminogen Activator and Its Inhibitor-1 in Acute Rat Spinal Cord Injuries

目的观察大鼠脊髓急性损伤时组织型纤溶酶原激活剂（t－PA）和纤溶酶原激活剂抑制因子1（PAI－1）表达的变化，了解t－PA、PAI－1在脊髓急性损伤后所起的作用。

Objective To observe the changes of tissue-type plasminogen activator ( t-PA ) and plasminogen activator inhibitor-1 ( PAI-1 ) expression in acute rat spinal cord injuries ( SCI ), to learn about the effect of t-PA and PAI-1 on the process of acute spinal cord injury .