空间记忆

维生素B6对生长期大鼠空间记忆行为及长时程增强的影响

Effects of dietary vitamin b_6 on spatial memory and hippocampal long-term potentiation in growing rats

空间记忆专长（spatialmemoryexpertise）是记忆研究的重要领域之一。

Spatial memory expertise is one of the most important fields of memory expertise research .

目的：研究和阐明组胺H1受体阻断剂对大鼠空间记忆的作用机制。

ATM : To evaluate effects of certain H1-antagonists on spatial memory with 8-arm radial maze performance of rats .

调心方对氧化损伤型类AD大鼠空间记忆能力和脑线粒体呼吸功能的影响

Effect of Heart Benefiting Recipe on Spatial Memory and Brain Mitochondrial Respiratory Function of Oxidative Damaged AD Rats

颞叶癫痫大鼠海马CA1区突触可塑性与空间记忆能力关系的研究

The relationship between the synaptic plasticity in CA_1 region in hippocampus and the space memory ability in temporal lobe epileptic male rats

结论：中枢组胺H3受体与大鼠空间记忆的调节密切相关，而且其作用与胆碱能神经相关。

CONCLUSION : The brain histamine H3-receptor antagonists are highly related to the spatial memory , and this action may be due to cholinergic neurons .

鱼油DHA对小鼠空间记忆和明暗反应的影响

Effects of DHA from Fish Oil on the Learning and Memory in Mice

REM睡眠剥夺对大鼠空间记忆、海马CaN的影响及FK506的干预作用研究

Effect of REM Sleep Deprivation and FK506 Intervention on Spatial Memory and Hippocampal Calcineurin in Rats

大量文献表明，LTP及LTD与空间记忆紧密相关。

A large body of literature that suggests , LTP / LTD and spatial memory is closely related to .

不同训练方式建立大鼠空间记忆后海马结构NMDA受体表达的变化

Changes of NMDA receptor expression in rat hippocampal formation after establishment of spatial memory by different training modes

结论：音乐刺激能提高大鼠空间记忆能力，增强海马神经元NMDA受体及编码NMDA受体的mRNA表达。

CONCLUSION : Music can improve the spatial memory of rats and increase the expression of NMDA receptor and its mRNA in hippocampus .

结论：调心方能够通过下调AD大鼠脑组织NFκB转录因子和APPmRNA表达水平，减少Aβ产生，改善AD大鼠的空间记忆能力。

Conclusion : HBR can reduce the produce of A β through decreasing the level of APP mRNA and NF - κ B transcription factor so that improves the space memory .

大量研究表明，海马神经元突触的NMDA受体在空间记忆的信息处理过程中起着重要的分子开关的作用。

A large number of studies demonstrated that NMDA receptor in hippocampus synapes serves as a gating switch during the spatial memory information procession .

即内嗅皮层orexinA受体参与了且提高了空间记忆能力。

That is , orexin A receptors in entorhinal cortex are involved in spatial memory . 5 .

结论经VRT测试后发现，ACI患者存在明显的视觉空间记忆损伤，这种认知功能损伤可能与脑组织受损有一定关系。

Conclusion There existed significant visual-spatial perception impairment in ACI patients , which attributed partially to lesion of cerebral tissue .

方法：迷宫观察动物的空间记忆能力，同时检测海马一氧化氮（NO）含量和一氧化氮合酶（NOS）活性。

Methods : Morris water maze was used to detect the spatial learning and memory , contents of NO and activities of NOS in hippocampus were measured during the test .

Meynert基底核注射冈田酸致大白鼠空间记忆障碍

Injection of Okadaic Acid into the Nuclei Basalis of Meynert Induced Spatial Memory Deficit in the Rat

结论颞叶癫痫大鼠海马CA1区神经毡内突触损害和活力可能是导致其空间记忆能力下降的重要机制。

Conclusion The injury of synaptic ultrastructure of CA1region in hippocampus may be an important mechanism underlining the damage of space memory ability in temporal lobe epileptic male rats .

胆碱酯酶抑制剂TAK-147对大鼠空间记忆的作用

Effects of TAK-147 , a novel acetylcholinesterase inhibitor , on spatial memory deficit as evalua-ted by Morris water maze of rats

为探讨衰老对空间记忆能力的影响，选用健康雄性SD大鼠，青年组（3月龄）20只，老年组（26月龄）40只，进行Morris水迷宫行为学测定。

To explore the role of aging factor for space memory , 60 male healthy SD rats , of which 20 were young ( 3 months ) and 40 old ( 26 months ), were used for behavior examination with Morris water maze .

TAK-147剂量依赖性地改善了癫痫诱发的空间记忆再现障碍，包括参考记忆和工作记忆。

TAK-147 showed an ameliorating effect on memory impairment induced by epilepsy , including reference and working memory in a dose-dependent manner .

结论h-APOE4基因与血清胆固醇水平有关，h-APOE4基因及h-APP基因的异常表达对实验鼠的空间记忆能力有影响。

Condusions The results suggest the apo E_4 gene may be related to the higher serum cholesterol level , and the overexpression of h-apo E_4 , and h-APP gene possibly impairs the primitive working memory capacity .

结果发现，Meynert基底核注射OA后，Ach水平降低，τ蛋白在Ser198/Ser199/Ser202，Ser396/Ser404位点发生过度磷酸化，并伴有大鼠空间记忆障碍。

It was found that injection of okadaic acid into the Meynert nucleus basalis of rat brain induced hyperphosphorylation of tau at Ser-198 / Ser-199 / Ser-202 and Ser-396 / Ser-404 epitope , and decreased acetylcholine level accompanied with special memory deficit .

分别用Y-迷宫和水迷宫检测小鼠的分辨学习记忆和空间记忆行为：高效液相色谱分析大脑前皮层和海马组织的谷氨酸（Glu）和γ-氨基丁酸（GABA）含量。

Discriminating learning and memory performance was tested using Y-maze , and spacial memory was detected using water maze . After behavior test , levels of glutamate ( Glu ) and GABA in fore-cortex and hippocampus were assessed using high performance liquid chromatography ( HPLC ) .

方法利用低压舱模拟2800m、3600m及4400m高度缺氧暴露1h，考察18名健康男性青年的记忆长廊、记忆扫描、连续识别记忆和空间记忆测验绩效的变化。

Method Tests of pattern memory , scanning memory , continuous recognition memory and space memory were conducted on 18 healthy young male subjects during exposure to 300 m ( control ), 2800 m , 3600 m and 4400 m altitude in hypobaric chamber .

目的：探讨慢性癫痫对大鼠空间记忆再生能力的影响，检测组胺前体物质组氨酸和胆碱酯酶抑制剂TAK-147对癫痫诱发记忆障碍的作用。

Objective : To investigate the influence of chronic epilepsy on spatial memory retrieval in rats , and to evaluate the effects of TAK-147 , an acetylcholinesterase inhibitor , and histidine , the precursor of histamine , on the amnesia induced by epilepsy .

经过改良的评价大鼠空间记忆能力的交替电刺激Y型迷宫

Improved alternative electro-stimulus Y-maze for evaluating the spatial memory of rats

模型组小鼠空间记忆能力下降。

The spatial learning memory ability in the model group reduced .

舒降之对颈动脉狭窄大鼠空间记忆改变的实验研究

Effect of Statins on spatial memory of rats with carotid artery stenosis

溴甲烷对大鼠体格发育和空间记忆发育的影响

Effects of methyl bromide on physical and space memory development in rats