磺脲类药物

在最近一个中位时间为4年的糖尿病进展试验中，用磺脲类药物治疗后也观察到了相似的情况。

A similar pattern with sulfonylureas was observed more recently in A Diabetes Outcome Progression Trial ( ADOPT ), over a median of4.0 years ( 10 ) .

磺脲类药物对胰岛β细胞凋亡影响的研究进展

Progress about the effects of sulfonylureas on islet β cells apoptosis

应用诺和灵R治疗磺脲类药物继发失效2型糖尿病的临床观察

Efficacy of Novolin R on type 2 diabetes mellitus patients with secondary failure to sulfonylurea

格列本脲对糖尿病及正常大鼠心肌磺脲类药物受体mRNA的影响

Effects of glibenclamide on mRNA level of ATP-sensitive potassium channels of heart in normal and streptozotocin induced diabetic rats

目的：调查糖尿病（DM）患者磺脲类药物受体基因16外显子-3T→C多态性与2型DM相关性。

Objective : To explore relationship between sulfonylurea receptor gene polymorphism and type 2 diabetes mellitus in Chinese subjects .

目的：观察磺脲类药物继发失效的2型糖尿病应用诺和灵R的疗效。

Objective : Studing the efficacy of the Novolin R in the treatment of type 2 diabetes mellitus patients with secondary failure to sulfonylurea .

目的探讨链脲佐菌素诱发的糖尿病模型大鼠的胰腺组织中自由基清除剂sodmRNA和磺脲类药物受体SURmRNA的表达，了解糖尿病时胰腺SOD和SUR的关系。

Objective Probing into the expression of scavenger SOD and SUR 's mRNA in pancreatic tissue of diabetic rats induced by streptozocin to understand relationships between SOD and SUR .

目的：探讨2型糖尿病（T2DM）与磺脲类药物受体1（SUR1）基因多态性的关系。

Objective : To study whether the polymorphism of human sulfonylurea receptor ( SUR 1 ) gene correlated with type 2 DM in Tianjin .

目的探讨缺血再灌注及缺血预适应（IPC）状态心肌磺脲类药物受体（SUR）亚型SUR2的分布及表达特征。

Objective To investigate the characteristics of expression and regional distribution of sulfonylurea receptor subtype 2 ( SUR2 ) in the reperfusion and ischemic preconditioning ( IPC ) rat heart .

目的：探讨磺脲类药物受体（SUR1）不同基因型与体质量指数（BMI）、胰岛素抵抗之间的关系。

Objective : This study was to investigate the relationship among allelic frequency of sulfonylurea receptor-1 gene ( SUR1 ), body mass index ( BMI ) and insulin resistance in gestational diabetes mellitus ( GDM ) .

采用动态血糖监测系统比较磺脲类药物治疗效果不佳的2型糖尿病患者睡前联合甘精胰岛素或中性鱼精蛋白锌胰岛素（NPH）治疗12周后血糖谱的变化。

With the continuous glucose monitoring system , daily blood glucose profiles were compared in type 2 diabetic patients treated with glargine or neutral protamine hagedorn ( NPH ) at bedtime for 12 weeks . The blood glucose levels in these patients were previously not well controlled with sulfonylureas .

自由基代谢和磺脲类药物受体关系的初步研究

Preliminary study of association between metabolism of free radical and sulfonylurea receptor

人胰岛素在磺脲类药物继发失效中的疗效观察

Clinical effect of Human insulin in secondary failure of sulfonylureas

妊娠期糖尿病与磺脲类药物受体基因1多态性的相关性研究

Study of the Association between Gestational Diabetes Mellitus and Sulfonylurea Receptor-1 Gene Polymorphism

高血糖对糖尿病大鼠胰腺β细胞磺脲类药物受体的影响

Effect of hyperglycemia on sulfonylurea receptor of β cells in pancreas of diabetic rats

结论：磺脲类药物预处理可以取消经典缺血预处理对在体大鼠缺血再灌注心肌损伤的保护效应。

Sulfonylurea pretreatment can eliminate the protective effect on ischemic reperfusion injured myocardium in rats .

磺脲类药物受体基因多态性与妊娠期糖尿病肥胖及胰岛素抵抗的关系

Relationship between Sulfonylurea Receptor-1 Gene Polymorphism and Insulin Resistance in Obesity and Gestational Diabetes Mellitus

二甲双胍和一般磺脲类药物时口服降糖药物的治疗基础。

Metformin and a generic sulfonylurea should be the basis of oral glucose lowering therapy .

经穴强化埋线联合中药注入治疗磺脲类药物继发失效机理的研究

Effects of Chinese Medicinal Injection Plus Catgut Implantation at Acupoint on Diabetics with Secondary Sulfonylureas Failure

胰淀素对大鼠胰岛β细胞分泌胰岛素及磺脲类药物继发失效机制的研究

Studies of Mechanisms of Amylin on Insulin Release from Rat Pancreatic β Cells and Sulfonylureas Secondary Failure

磺脲类药物受体亚型在缺血及缺血预适应大鼠心肌中的定位与分布研究

Studies on expression and regional distribution of sulfonylurea receptor in the reperfusion and ischemic preconditioning rat heart

长期高血糖对继发磺脲类药物失效患者胰岛β细胞功能的影响

Effect of chronic hyperglycemia on islet β cells function in type 2 diabetes mellitus with secondary sulfonylureas failure

磺脲类药物继发失效患者不同治疗方案的成本-效果及对生存质量的影响

Different Therapeutic Regimens for Diabetic Patients with Sulfonylureas Secondary Failure : Cost-Effectiveness Analyses and Evaluation of Life Quality

国产匹格列酮片单用及与磺脲类药物合用治疗2型糖尿病的临床疗效

Pioglitazone Hydrochloride Monotherapy or in Combination with Sulfonylurea Therapy Improves Glycemia Control in Patients with Type 2 Diabetes

继发性磺脲类药物失效的2型糖尿病三种治疗方式的观察与评价

An Observation of Three Therapeutic Methods in the Treatment of Type 2 Diabetes Mellitus with Secondary Failure of Sulfonylurea

目的探讨胰岛素短期强化治疗恢复糖尿患者对磺脲类药物的敏感性。

Objective To research the effects of short-term intensive insulin treatment on regaining the sensitivity of sulfonylureas in diabetes patients .

一项独立进行的流行病学研究发现，使用磺脲类药物的患者癌症死亡率高于使用二甲双胍的患者。

An independent epidemiological study found that users of sulfonylureas were at higher risk of cancer-related mortality than metformin users ( 7 ) .

这些药物，比如磺脲类药物和格列萘类药物可以刺激胰腺产生更多的胰岛素或提高循环胰岛素量。

Those are drugs , such as sulfonylureas and glinides , which stimulate the pancreas to secrete more insulin or raise circulating levels of insulin .

目的观察Ⅱ型糖尿病人对磺脲类药物继发性失效加用拜糖平的疗效。

Objective To study the therapeutic efficacy of acarbose in addition to sulfonylurea drugs for treatment of type ⅱ Diabetes Mellitus ( NIDDM ) with secondary failure to sulfonylurea medication .

亚莫利是磺脲类药物的一种，已经应用十来年，是糖尿病治疗处方中的最常用的药物中的一种。

It 's a member of the class of agents known as sulfonylureas that have been available for decades and represent one of the most commonly prescribed classes of diabetic therapy .