白假丝酵母菌

白假丝酵母菌随机扩增多态DNA分型及其流行趋势分析

The genotyping of Candida albicans by random amplified polymorphic DNA and the epidemiological analysis

白假丝酵母菌菌丝壁蛋白1（HWP1）是已知的白假丝酵母菌芽管和菌丝的特异性蛋白之一，因其在假丝酵母菌的黏附过程中起重要作用而成为近年来的研究热点。

It is known that Candida albicans hyphal wall protein 1 ( HWP1 ) is one of specific protein of Candida albicans germ tubes and hyphae . It is of great importance in the adhesion , which makes it to be a focus of researches .

达克宁栓使阴道内白假丝酵母菌数量明显减少，乳酸杆菌数量明显下降（P<0.05），而阴道pH无变化。

Miconazole Nitrate Suppositories reduced obviously the quantity of Candida albicans and Lactobacillus ( P < 0.01 ); there was not a distinct discrepancy between after treatment and before treatment for pH value ( P > ( 0.05 )) .

0.31%初提液作用15min、0.62%提纯液作用30min可杀灭白假丝酵母菌7374株和红色毛癣菌6180株。

Albicans strain 7374 and T. rubrum strain 6 ? 180 were killed after treated with 0.31 % of the original oiliness extract for 15 min and 0.62 % of the purified oiliness extract for 30 min.

菌丝相白假丝酵母菌长片段基因表达系列分析文库的构建及结果分析

Long serial analysis of gene expression in hyphal cells of Candida albicans

白假丝酵母菌不同菌株荚膜的对比性观察株具有荚膜的白假丝酵母菌的分离与鉴定

Observation and Comparison on Different Strains of Candida Albicans

化疗患者口腔白假丝酵母菌的分布及基因分组研究

Distribution and genotypic subgroup of oral Saccharomyces albicans isolated from cancer patients receiving chemotherapy

白假丝酵母菌感染及分型方法的研究进展

Advance on Candida albicans infection and genotyping methods

观察白假丝酵母菌临床菌株的荚膜结构并探讨其形成条件。

To observe and confirm the capsule structure of a clinical strain of Candida albicans .

药物流出泵基因在白假丝酵母菌生物膜耐药性产生机制中的作用

Roles of drug efflux pump genes in the mechanism of Saccharomyces albicans biofilm drug tolerance

目的构建菌丝相白假丝酵母菌长片段基因表达系列分析文库并探讨其基因表达特点。

Objective To observe the characteristics of gene expression in the hyphal cells of Candida albicans .

同时可能有其他机制参与临床白假丝酵母菌耐药性的生成。

Other mechanisms may also participate in the development of drug resistance in the clinical Candida albicans strains .

3种材料中，树脂性材料最易粘附白假丝酵母菌，其次是烤瓷材料，最不易粘附白假丝酵母菌的材料是金属材料。

The Candida Albicans was easiest to adhere the resin materials , than is porcelain , and metal .

因此本实验针对阴道白假丝酵母菌的二相性与酶活性、酶活性与毒力的关系开展了研究，并探讨外环境的变化对酶活性强弱的影响。

In this study , we discuss the difference between enzymic activity and virulence of dimorphism in C.albicans .

结论：白假丝酵母菌的荚膜厚度可因不同菌种（株）和不同环境而有差异；

Conclusion : the thickness of the capsule of candida albicans is changeable because of different strains and conditions .

当合并白假丝酵母菌和滴虫感染时，其病原体对唾液酸酶活性检测未产生显著影响。

The complication of infection of candida vagitis and trichomonas showed no marked effect of the activity of sialidase test .

医院感染病原菌以白假丝酵母菌为主，占18.18%；社区感染病原菌以支原体为主占20.93%。

Hospital infection pathogens were mostly Candida albicans , accounting for 18.18 % ; community-acquired infection pathogens was mainly mycoplasma , accounted for 20.93 .

临床试验：试验组在治疗后口腔黏膜白假丝酵母菌数量明显降低，口腔链球菌数量升高，较治疗前差异均有显著性（P<0.01）；

Clinical studies : there was a distinct reducing in the quantity of Candida albicans after treatment in study group ( P < 0.01 ) .

结论消炎痛能抑制白假丝酵母菌菌丝和芽管的生成，极有可能成为一种很有前途的治疗外阴阴道炎症的药物。

Conclusion Indomethacin can suppress the filamentous growth and germination of Candida albicans , and it may be a promising drug of treating vulvovaginal candidiasis .

是用患有肾念珠菌病的患者的小便做的直接涂片，显示有菌丝的白假丝酵母菌。以出芽方式增殖，在组织内可见芽生孢子和假菌丝。

Direct smear of urine from a patient with candidiasis of the kidney showing C.albicans in mycelial or tissue phase with blastoconidia budding from the pseudohyphae .

方法：建立白假丝酵母菌的生长梯度模型，并引入甲型链球菌与铜绿假单胞菌或其培养后上清；

Methods : Candida albicans growth models of different concentration were established and they were mixed with α - Streptococcus or Pseudomonas aeruginosa or their supernant .

除特比奈芬外，白假丝酵母菌和非白假丝酵母菌对唑类药物有不同程度的耐药，且非白假丝酵母菌的耐药率较高，二者差别有统计学意义。

Except terbinafine , Candida albicans strains were resistant to Azoles at different degrees , the non-Candida albicans resistence rates to Azole drugs were higher than Candida albicans .

结果20株放化疗患者口腔假丝酵母菌感染菌株中非白假丝酵母菌5株，对5-氟胞嘧啶全部敏感，对氟康唑和伊曲康唑的耐药比例分别为25%和40%；

Albicans in all Candida spp. were 25 % . All strains were sensitive to 5-flucytosine , 25 % stains were resistant to fluconazole and 40 % stains were resistant to itraconazole .

结果所得30个菌株中白假丝酵母菌、光滑假丝酵母菌、热带假丝酵母菌、中间假丝酵母菌的构成比分别为1333%、3333%、2667%、1000%；

Results : Among all thirty strains , the ratio of candida albicans , candida glabrata , candida tropicalis and candida intermedial was 13.33 % 、 33.33 % 、 26.67 % 、 10.00 % separately ;

近年来的动物实验和临床证据均表明，高雌激素水平使个体对外阴阴道假丝酵母菌病的易感性增加，雌激素促进白假丝酵母菌菌丝形成及增殖，使其毒力增强。

Recent animal experiments and clinical observations demonstrated that high level of estrogen contributes to the susceptibility to vulvovaginal candidiasis . Estrogen promoted hyphal formation and proliferation of C. albicans , leading to virulence enhancement .

革兰氏阴性菌以肺炎克雷伯菌肺炎亚种（18/62株，29.03%）为主，革兰氏阳性菌以金黄色葡萄球菌（17/22株，77.27%）为主，真菌以白假丝酵母菌（19/28株，67.86%）为主。

In Gram negative bacteria Klebsiella pneumoniae was the major one ( 29.03 % ) and in Gram positive bacteria Staphylococcus aureus was most prominent ( 77.27 % ) and Candida albicans was the main type of fungi ( 67.86 % ) .