甲肝减毒活疫苗

H2株甲肝减毒活疫苗安全性及免疫效果观察

Observation on safety and immune effect of live attenuated Hepatitis A vaccine ( H_2 strain ) with suspension absorption technique in rhesus monkey

冻干甲肝减毒活疫苗人群接种安全性观察

Observation of the security of freeze-dry live attenuated Hepatitis A vaccine in mass inoculation

地高辛标记RT-PCR检测甲肝减毒活疫苗的研究

Evaluation of the Titre of HAV Vaccine by Digoxigenin Labeling RT PCR

结论H2株冻干甲肝减毒活疫苗有良好的T细胞刺激能力。

Conclusion Freeze-dried Live attenuated hepatitis A vaccine ( H2-strain ) has good capacity to stimulate T lymphocyte .

建立快速灵敏特异的甲肝减毒活疫苗滴度的RT－PCR检测法。

Objective : A highly rapid , sensitive and specific RT-PCR method for evaluation of the titre of HAV attenuated live vaccine was established .

[结论]此法具有简便、灵敏、省时的优点，可代替常规组织培养ELISA法应用于甲肝减毒活疫苗感染性滴度检测中。

[ Conclusions ] This method is simple , sensitive and time - saving and may replace the cell culture ELISA for testing of liver attenuated HAV vaccine .

结论此法与常规RTPCR法相比具有更简便，判断标准更客观的优点，可代替组织培养法检测甲肝减毒活疫苗滴度。

Conclusions The above method is more convenient and objective compared with routine RT-PCR , which can be used to measure the titer of HAV live attenuated vaccine .

目的对接种H2株冻干甲肝减毒活疫苗后机体血中T淋巴细胞亚群的变化进行动态观察。

Objective To observe the kinetic changes of blood T lymphocyte subsets induced by the freeze-dried live attenuated hepatitis A vaccine ( H2-strain ) .

目的观察本县1～14岁儿童及重点行业人群试用国产H2株甲肝减毒活疫苗免后持久性。

Objective To observe the immune persistence of domestic HA vaccine of H 2 strain in children aged 1 to 14 years and in key vector population .

观察组接种甲肝减毒活疫苗（H2株），对照组接种乙肝基因工程疫苗。

Group one was inoculated with live attenuated hepatitis A vaccine ( H 2 strain ) . Group two was inoculated with recombinant hepatitis B vaccine of gene .

目的研究甲肝减毒活疫苗（以下简称甲肝疫苗）治疗慢性乙型肝炎（CHB）的机制。

AIM To investigate the mechanisms of the treat - ment with attenuated hepatitis A virus live vaccine ( AHAVLV ) in chronic hepatitis B ( CHB ) .

目的鉴别在接种甲肝减毒活疫苗（H2株）后23天发生的一例甲型肝炎，其病原体是疫苗株还是野毒株。

Objective To distinguish whether the etiologic agent was the vaccine strain or wild strain of HAV for vaccine Zheng who suffered from hepatitis A on day 23 after inoculation with the live attenuated hepatitis A vaccine , H2 strain .

结论国产甲肝减毒活疫苗（H2株与LA1株）具有很好免疫原性与保护效果，可与国外灭活疫苗相媲美。

Conclusion Both strains of the live attenuated hepatitis A vaccines have good immunogenicity and high protection against clinical disease , the efficacy to prevent subclinical infection is not significant .

目的探讨国产规范化甲肝减毒活疫苗（LA-1株）大规模免疫后的长期保护效果。

Objective To evaluate the long_term protective efficacy of large_ scale immunization with a standardized live attenuated hepatitis A vaccine ( LA_1 strain ) .

目的应用核酸扩增产物测定的固相杂交酶联显色法（RT-PCR-ELISA）检测甲肝减毒活疫苗病毒滴度。

Objective To evaluate the RT-PCR-ELISA method applied for testing live attenuated hepatitis A vaccine titer . Methods A solid phase hybridization-enzyme colorimetric detection method was used for detecting specific nucleic acid .

国产甲肝减毒活疫苗免疫接种后抗体水平检测分析

Anti - HAV Level Surveillance of Domestic HAV Attenuated Vaccine Immunization

微量免疫荧光法检测甲肝减毒活疫苗病毒滴度

A micro - immunofluorescent method for testing of live attenuated HAY vaccine

甲肝减毒活疫苗流行病学效果初步研究

A Preliminary Report of A Randomized and Controlled Trial of Attenuated Live HAV Vaccine

甲肝减毒活疫苗口服免疫动物后的抗体反应

Antibody Response in Animals Immunized After Oral Delivery of Attenuated Live Hepatitis A Vaccine

结论甲肝减毒活疫苗加强免疫能诱导很好的免疫记忆反应，其免疫学效果与史克灭活疫苗相当；

Conclusions A booster dose of live attenuated vaccine can induce secondary immune response well .

目的评价冻干甲肝减毒活疫苗在人群接种的安全性。

Objective To evaluate the security of freeze-drying live attenuated hepatitis A vaccine in mass inoculation .

国产甲肝减毒活疫苗接种后3年流行病学效果研究

Epidemiologic observation of homebred hepatitis A attenuated live vaccine during the first 3 years after vaccinated

目的对冻干甲肝减毒活疫苗毒种与成品检定中的关键性项目的检定方法进行优化。

Objective To optimize the testing method of key items for freezed-dried live attenuated hepatitis A vaccine virus seed and final product .

研制冻干甲肝减毒活疫苗，提高疫苗的稳定性，便于保存及运输，保证疫苗的接种效果。

Lyophilized attenuated live hepatitis A vaccine was studied for raising its stability in order to store and transport and for guarantee its vaccination effect .

甲肝减毒活疫苗及加服牛磺酸在接种乙肝疫苗免疫失败儿童中的致免疫性

Immunogenicity of attenuated hepatitis A virus ( HAV ) vaccine and combined oral Taurine in the children failed to respond to hepatitis B virus ( HBV ) vaccine

结论所建立的方法具有操作简便、快速的优点，有望替代细胞培养法作为用于检测甲肝减毒活疫苗滴度的常规方法。

Conclusion The above method is more swift and convenient , and has the potential to be used to measure the titer of HAV live attenuated vaccine instead of traditional method .

结果冻干甲肝减毒活疫苗具有与液体疫苗相同的安全性及免疫原性。

The ratio of vaccine to protective agent was 3.5 : 1 . Results The safety and immunogenicity of the freeze - dried vaccine were identical to those of liquid vaccine .

目的研究规范化H2株甲型肝炎（简称甲肝）减毒活疫苗免疫学效果和抗感染能力。

Objective To assess immunogenicity of a standardized live attenuated hepatitis A vaccine ( H 2 strain ) .

目的探讨甲型肝炎（甲肝）减毒活疫苗接种后的病毒水平传播。

Objective To investigate the horizontal transmission of viruse after inoculation with live attenuated hepatitis A vaccine .

儿童甲肝、风疹减毒活疫苗同时免疫效果观察

Efficacy of a Combined immunization with a Live Attenuated Hepatitis A Vaccine and a Live Attenuated Rubella Vaccine