水杨酸钠

目的：检测水杨酸钠对耳蜗血流量（cochlearbloodflow，CoBF）的影响，探讨水杨酸盐耳毒性发生的机制。

Objective : To determine the effects of sodium salicylate on cochlear blood flow ( CoBF ) and explore the mechanism of salicylate ototoxicity .

以维生素B2和水杨酸钠为例，对方法的应用进行了说明。

Application of the method was shown by taking vitamin B2 ( VB 2 ) and sodium salicylate ( SAL ) as examples .

结论：水杨酸钠能促进豚鼠螺旋神经节细胞NF-κB蛋白表达；

Conclusion : Sodium salicylate can promote the protein expression of NF - κ B in cochlear spiral ganglion cells .

三个水杨酸钠给药组以B组表达最高D组表达最低。

The protein expression of B group was the highest in group B and the lowest in group D in the three sodium salicylate administrated groups .

目的：制备pH依赖和时间双重控制的4-氨基水杨酸钠结肠定位给药系统，并考察其体外释药行为。

OBJECTIVE To prepare a new pH-dependent and time-controlled coated tablet for colon-specific targeting and to evaluate the drug release profile in vitro .

水杨酸钠对人早幼粒细胞白血病HL-60细胞的影响

Effect of sodium salicylate on human acute promyelocytic leukemia HL-60 cells

水杨酸钠静脉滴注对家兔EP性发热的解热效应观察

Observation of the antipyretic effects of sodium salicylate on EP-induced fever in rabbits

水杨酸钠给药对小鼠下丘核NGBmRNA和蛋白表达的影响

Effects of sodium salicylate on expression of NGB mRNA and protein in inferior colliculus neurons of mice

GAP-43和ARC基因在水杨酸钠组大鼠听皮层的表达明显高于其他对照组，差异有显著统计学意义。

GAP-43 and ARC protein expression of auditory cortex in the sodium salicylate groups was significantly higher than the other three control groups .

应用卡那霉素（K）、氧氟沙星（O）、对氨基水杨酸钠（P）为基础化疗方案，加用1或2种未曾应用过的抗痨药物，平均治疗3.3个月。

The authors added 1 ~ 2 kinds of anti TB drugs never used before in each case to KOP ( Kanamycin , Ofloxacin , Sodium Aminosalicylate ), with a mean 3.3 months treating course .

为了研究MAPK信号的作用，我们比较了茴香霉素和水杨酸钠作用下牙齿相关的分化标志的表达。

To examine the roles of MAPK signals , we compared the effects of anisomycin and sodium salicylate on the expression of tooth-related differentiation markers .

目的：观察水杨酸钠给药对幼年豚鼠螺旋神经节谷氨酸脱羧酶（GAD）蛋白表达和听性脑干诱发电位（ABR）阈值的影响。

Objective : To study the effects of sodium salicylate on the expression of GAD protein and ABR threshold in spiral ganglion of juvenile guinea pigs .

我们发现该药物显著地压制GABA神经元的自发活动水平，提示水杨酸钠通过提高中枢听觉系统的兴奋性诱导耳鸣。

It has been found that NaSal significantly suppresses the functional activity of GABA neurons , suggesting that NalSal raises excitability in the central auditory system to induce tinnitus .

家兔静脉灌注水杨酸钠对EGTA性发热及其脑脊液cAMP，PGE2含量的影响

The effects of sodium salicylate on febrile response and changes of cAMP and PGE_2 level in c. s. f , after intraventricular perfusion of EGTA in rabbits

我们发现水杨酸钠在脑片上降低抑制性突触后电流（IPSC）的幅度，同时在培养的海马神经元上直接抑制GABAA受体（GABAAR）介导的反应。

Salicylate significantly inhibited the amplitudes of both evoked and miniature inhibitory postsynaptic currents ( IPSCs ), and directly reduced GABA_A receptor ( GABA_AR ) - mediated responses in cultured rat hippocampal neurons .

目的：观察水杨酸钠诱导大鼠肾上腺嗜铬细胞瘤细胞（PC12）凋亡的作用并初步探讨其机制。

AIM : To observe whether sodium salicylate could induce the apoptosis of adrenal gland chromaffin tumor cell ( PC12 ), and primarily explore the possible mechanism .

PC-602对次氯酸钠的稳定性无影响，葡萄糖酸钠和水杨酸钠复配具有协同增效作用.但可加速次氯酸钠的分解速率。

For PC-602 , there are no influence on the stability of sodium salicylate can be accelerate the rate of decomposition of sodium hypochlorite .

正常大鼠ABR波形稳定，多次注射水杨酸钠的大鼠ABR波形分化差，各波幅下降，ABR阈值上升、II波潜伏期延长与实验前相比具有统计学意义。

In normal rats , ABR waveforms were stability . But rats after repeated injections of sodium salicylate , ABR waveforms were poorly differentiated , the amplitude decreased , ABR thresholds increased , II-wave latency was prolonged , as compared with the pre-test , there are statistics significance . 3 .

目的：探讨水杨酸钠耳毒性的发生机制。

Objective : To further understand the mechanism of salicylate ototoxicity .

对氨基水杨酸钠在壳聚糖修饰碳糊电极上的伏安行为研究

Volt-ampere characteristic of sodium aminosalicylate on chitosan modified carbon paste electrode

荷移反应用于对氨基水杨酸钠的测定

Application of charge transfer reaction in the determination of aminosalicylate sodium

水杨酸钠对大鼠下丘神经元钾通道的抑制作用

Inhibition of salicylate on potassium channels in rat inferior colliculus neurons

水杨酸钠改善大鼠胰岛素抵抗的实验研究

Experimental study on sodium salicylate improved insulin resistance in rats

水杨酸钠在极性溶剂中的荧光和激光特性的研究

Fluorescence and laser characteristics of sodium salicylate in polar solvents

4-氨基水杨酸钠结肠黏附微丸的制备及黏附性能考查

Preparation and adhesive characterization of colon adhesive pellets of sodium 4-amino salicylate

对氨基水杨酸钠对亚慢性铅暴露大鼠海马超微结构的影响

Effects of sodium para-aminosalicylic acid on hippocampal ultramicro-structure of subchronic lead-exposed rats

应用玻碳电极测定血清样品中含对氨基水杨酸钠的研究

Study on the Determination of Para-aminosalicylate in Serum with Classy Carbon Electrode

水杨酸钠作用后大鼠耳蜗基因表达谱改变的研究

Differentially Expressed Gene Profiles of Cochlea in Rats Induced by Sodium Salicylate Injection

4-氨基水杨酸钠结肠靶向胶囊定位研究

Localization study on sodium 4-amino salicylic acid colon-targeting capsule

微量水杨酸钠对小鼠抗疲劳作用的量效关系分析

Analysis on Dose-Effects Relationship about Anti-Fatigue of Micro Dose Sodium Salicylate of Mice