抗毒素

Vero细胞法检测白喉抗毒素的研究

Vero Cell Assay for Determination of Diphtheria Antitoxin Titres

结论通过对比认为15U／ml的破伤风抗毒素皮试液为最佳皮试液。

Conclusion Tetanus antitoxin skin test solution with concentration of 15u / ml is optimus .

应用双抗原ELISA夹心法检测破伤风抗毒素效力的试验

Detection of tetanus antitoxin titers by double antigen sandwich ELISA

在这一过程中，植物细胞壁组成成分发生改变，表达各种病原相关蛋白（PR蛋白），并合成多种植物抗毒素。

Changes in cell wall composition , production of pathogenesis-related ( PR ) proteins , and synthesis of phytoalexins are associated with resistance .

白藜芦醇（resveratrol，3,4′，5-三羟基二苯乙烯）为多酚类化合物，是一种存在于自然界的植物抗毒素。

Resveratrol ( 3,4 ' , 5-trihydroxystilbene ) is a phytoalexin which is present in a number of plant species .

其中早期气管切开、补充能量及鞘内注射破伤风抗毒素（TAT）患者疗效均较好。

But the patients treated with early tracheostomy , nutrition supplement and intrathecal injection of TAT recovered better .

13株单克隆抗体均为IgG1亚类，经毒素抗毒素中和试验测定，13株单克隆抗体中，12株具有中和ε毒素的活性。

All antibodies belongs to IgG1 subclass . Results of toxin-antitoxin neutralization show that 12 out of 13 monoclonal antibodies have the activity of neutralizing e-toxin .

这些HSP加速了木质素的合成，并诱导植物抗毒素等产生，从而提高薯根的抗病性，保持耐贮不腐烂。

Induced HSP enhances biosynthesis of lignins and phytoalexins in roots , thus increasing diseases resistance and storage tolerance in heat-shocked roots .

人红细胞20S蛋白酶体的蛋白质组学表征及不同来源20S蛋白酶体异质性的研究白喉抗毒素是异性蛋白。

Proteomic Characterization of Human Erythrocyte 20S Proteasome and Analysis of Species-dependent 20S Proteasome Heterogeneity Diphtheria antitoxin is a foreign protein .

目的：白藜芦醇（resveratrol）是一种存在于葡萄皮及红酒中的多酚类植物抗毒素。

Objective : Resveratrol ( trans-3 , 4 ' , 5-trihydroxystilbene ) is a phenolic phytoalexin present in grape skins and wines , especially red wines .

动物实验证明此重组抗原具有良好的免疫原性，1μg免疫剂量可使动物产生1～2IU/ml的破伤风抗毒素，ELISA抗体滴度可达1∶800。

Animal test showed good immunogenicity of the recombinant antigen . The antigen at a dosage of 1 μ g could induce 1 2 IU / ml of antitoxin with an ELISA titer of 1 ∶ 800 .

注射破伤风抗毒素发生Arthus反应1例

A Case of Arthus Reaction Induced by Injecting of Tetanus Antitoxin

目前唯一有效的防治手段是及时注射精制破伤风抗毒素（TAT）或人破伤风免疫球蛋白（TIG），以中和血液中游离的毒素。

At present , the unique effective therapy is to inject tetanus anti-toxin ( TAT ) or human tetanus immunoglobulin ( TIG ) into patient to neutralize the exotoxin .

对抗破伤风毒素人源单克隆抗体G2、G6、G2+G6与精制破伤风抗毒素进行了中和效力比较试验。

The toxin neutralizing activity was detected by human MAbs G2 、 G6 、 G2 + G6 and horse anti tetanus antitoxin .

白藜芦醇（Resveratrol，简称Res）是一种植物抗毒素，是存在于数十种食物和药物中的一种具有保健功能的成份。

Res ( resveratrol ) is a kind of plant endotoxin . It is a kind of composion with health care function existing on several dozen food and one of medicine .

BA-ELISA法用于血清中白喉抗毒素检测的实验探讨

The Experimental Approach on the Detection of Diphtheria Antitoxin in Serum by means of BA - ELISA Method

白藜芦醇（resveratrol）是植物受外界刺激而产生的一类低分子量、具有生物活性的植物抗毒素（phytoalexin）。

Resveratrol is a kind of phytoalexin , which is low molecular weight , biologically active metabolite produced by plants as defense to various exogenous stimuli .

抗毒素是抵抗有毒物质并防止其产生有害作用的物质。ICP-MS测定木薯生产副产物的矿质元素和有害重金属元素

Antitoxin is substance that acts against a poisonous substance and prevents it from having a harmful effect . Application of ICP-MS to Detection of Mineral Elements and Heavy Metals in Cassava 's Byproducts

205名育龄妇女免前血清破伤风抗毒素达到自然保护水平者占37.56%，抗毒素GMT（滴度倒数，下同）为3.88±5.12HAu／ml。

The tetanus anti-toxin ( TAT ) titers of 205 ( 37 . 56 % ) women of childbearing age before immunization reached natural protective level , and GMT was 3 . 88 ± 5 . 12HAU / ml.

结果破伤风抗体阳性率44.22%，抗体阳性者破伤风抗毒素（阳性TAT）平均含量0.096U/ml。

Results The positive rate of tetanic antibody was 44 . 22 % . The average level of tetanus an-titoxin ( TAT ) in the cases of positive antibody was 0 . 096u / ml.

破伤风抗毒素阳性率从6905%上升至9881%，GMT由00332IU/ml上升为43801IU/ml。

4IU / ml. The positive rate of the anti-tetanus toxin rose from 69 05 % to 98 81 % , the GMT from 0 033 ? 2IU / ml to 4 3801IU / ml.

建立了旋转振荡法配制弗氏不完全佐荆（IFA）抗原，并在精制破伤风抗毒素（TAT）生产中，与传统方法配制的IFA抗原进行比较。

Established a rotating-shaking method for incomplete Freund 's . adjuvant ( IFA ) antigen 's preparation and compared this with IFA antigen which prepared by classic method when we produced highly finished tetanus antitoxin ( TAT ) .

应用IHA法对1318名15～45岁育龄妇女进行了破伤风抗毒素水平测定，阳性率8.80%，保护率7.97%，GMT0.0026IU／ml。

The tetanus anti-toxin ( TAT ) level of 1318 women aged 15 ~ 45 years were detected by IHA . The results showed that TAT positlve rate and protective rate were 8.80 % and 7.97 % , respectively , and GMT was 0.0026IU/mI .

介绍了破伤风抗毒素（TAT）皮试液的配制方法、剂量、浓度及皮试部位的选择、对皮试结果判定、注射方法及临床实践中使用TAT注意事项。

It introduced the influence of the preparing method , dose , concentration of tetanus antitoxin skin test fluid and selecting of location skin test on assessment of skin test result . It explained announcements for using TAT in clinical practice .

破伤风抗毒素（TAT）在临床上的使用比较多见，TAT皮试引起过敏性休克是过敏反应中最危险的一种，应引起基层医务人员的高度重视。

Tetanus antitoxin ( TAT ) is clinically extensively applied . However , compared with other allergic reactions , the allergic reaction aroused by TAT skin test is the most dangerous and should thus be highly valued by grass-roots unit medical workers .

迄今为止，已提供60剂抗毒素（20剂来自英国，30剂来自亚特兰大疾病控制和预防中心，10剂来自加拿大Sanofi-Pasteur），并且受感染严重的患者正在得到治疗。

To date , 80 doses of antitoxin ( 20 from the United Kingdom , 50 from CDC Atlanta and10 from Sanofi-Pasteur Canada ) have been provided , and severely affected patients are being treated .

表明这些人源单抗在中和毒力方面能够取代精制破伤风抗毒素，可满足临床试验需求。

These human monoclonal antibodies were novel replacement for clinical trial .

你多久能把抗毒素带来？

How soon can you be here with the antitoxin ?

三种佐剂对破伤风抗毒素质量的影响

Effect on the quality of Tetanus antitoxin immuned by three types adjuvant

破伤风抗毒素过敏反应二例

Report of two cases on anaphylactic reaction to tetanus antitoxin