微管结合蛋白
- 名microtubule-binding protein
![微管结合蛋白](../cache/1176410.jpg)
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资料综合:①由微管结合蛋白Tau形成的聚集体是许多神经退行性疾病的主要病理特征之一。
DATA SYNTHESIS : ① Pathological aggregation of the microtubule-associated protein Tau is a common feature of many neurodegenerative diseases .
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目的:检查老龄和青年大鼠睾丸间质组织中tau蛋白和微管结合蛋白的表达情况,籍此评价老龄大鼠睾丸衰退的发生机制。
Objective : To examine the expression of the tau protein and microtubule-associated proteins in the testis interstitium of aged and young rats .
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醋酸铅对ST-8814细胞神经丝蛋白、微管结合蛋白mRNA水平的影响
Effect of lead acetate on mRNA expression of neurofilament protein and microtubule associated protein in ST-8814 cell line
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目的:构建表达人微管结合蛋白4微管结合区(Microtubule-BindingDomain,MTB)的大肠杆菌工程菌。
Objective : To construct the engineered E. coli . strain which expresses microtubule-binding domain ( MTB ) of human microtubule-associated protein 4 ( MAP4 ) .
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以C8柱为固定相,研究了微管结合蛋白2中两段重要肽段(肽1,肽2)和猪胰岛素在反相色谱上的保留行为。
The Chromatographic retention behaviors of two peptides ( peptide 1 and peptide 2 ) from microtubule _ associated protein 2 ( MAP2 ) and porcine insulin in C8 hydrophobic ligand were studied .
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最近的研究的发现,在果蝇和爪蟾系统中,AuroraA能够磷酸化TACC(Transformingacidiccoiledcoil)蛋白,并招募TACC蛋白到中心体上,与微管结合蛋白一起参与调控中心体微管的稳定性。
Recently , Xenopus and Drosophila transforming acidic coiled coil ( TACC ) proteins have been found to be the substrates of Aurora A. After phosphorylation by Aurora A , TACC proteins are recruited to centrosomes , and then contribute to modulating centrosomal microtubule stability with microtubule associated proteins .
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人微管结合蛋白4微管结合区的体外表达
Expression of Microtubule Binding Domain of Human Microtubule-associated Protein 4
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结论:人微管结合蛋白4微管结合区具有微管结合活性。
Conclusion : recombinant MTB proteins of human MAP4 retained the MT-binding activity .
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植物微管结合蛋白的研究是目前植物细胞骨架研究的前沿领域。
Study of MAPs is now the cutting-edge research in the field of the cytoskeleton researches .
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微管结合蛋白是一类能够特异地与微管结合,参与调节微管结构与功能的结合蛋白。
Microtubule-associated proteins ( MAPs ) bind to microtubules specifically and are involved in the regulation of microtubule dynamics and its related functions .
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微管结合蛋白对微管骨架的组织和功能调控有重要的作用。
Microtubule associated proteins ( MAPs ) are the major factor involved in the regulation of microtubule ( MT ) dynamics and organization for functions of the MT cytoskeleton .
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在细胞分裂过程中,有丝分裂纺锤体控制染色体的分离。纺锤体是具有双极性的结构,由微管和微管结合蛋白组成。
Chromosome segregation during cell division is orchestrated by the mitotic spindle , a bipolar apparatus composed of microtubules and their associated proteins .
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微管列阵的转换需要微管结合蛋白的参与。
Microtubule-associated proteins ( MAPs ) are involved in the transformation of MT arrays .