异戊巴比妥

国产异戊巴比妥的杂质分离和结构分析

Study on the Isolation and Structure Determination of a Major Impurity in Domestic Amobarbital

TA对异戊巴比妥钠诱导的睡眠时间无延长作用，在高架十字迷路中与乙醇不发生相互作用；

TA did not produce the influence on amobarbital sodium sleeping and had no interaction with ethanol in the elevated plus-maze test .

报道了电极对苯巴比妥，硫喷妥，异戊巴比妥、苯妥英、利尿酸及水杨酸的电位响应特性及最佳pH与浓度区间。

The potentiometric response characteristics of the electrode with respect to thiopental , phenobarbital , amobarbital , phenytoin , ethacrynic acid and salicylate were studied and the optimum pH and concentration range of the electrode for different organic drugs were found .

实验方法：1.失血性休克模型的建立：Wister大鼠（体重250-300g）雌雄不限，用4.5%异戊巴比妥（80mg／kg）在25℃室温下腹腔内给药麻醉。

2 Medicine in experiment : amobarbital sodium ; Methods : 1 . Hemorrhagic shock model : Wister rats ( 250-300g ) were anesthetized with 4.5 % amobarbital sodium ( 80mg / Kg i.p. ) in room temperature ( 25 ℃) .

血及尿中微量苯巴比妥、异戊巴比妥的快速限量测定

Rapid estimation of traces of phenobarbital and amobarbital in plasma and urine

5乙，5异戊巴比妥酸对胆碱脱氢酶的抑制

Inhibition of choline dehydrogenase by amytal

减少醋酸引起的小鼠扭体次数，缩短兔股动脉出血时间而不影响凝血时间，延长异戊巴比妥钠对小鼠的催眠时间。

It shortened femoral artery bleeding time instead of cotting time in rabbits , and prolonged the hypnotic duration of sodium amobarbital in mice .

资料综合：异戊巴比妥实验曾被视为确定语言优势半球的金标准，测定过程为有创操作，有并发症的可能，同时获得信息少；

DATA SYNTHESIS : Wada test was once taken as the golden standard to identify dominant hemisphere of language , the process was an invasive operation , and there was possibility of complications and fewer information .