左氧氟沙星

左氧氟沙星与维生素C注射液的配伍稳定性

Compatibility of Levofloxacin Injection Combined with Vitamin C

左氧氟沙星三联与铋剂四联疗法根除HP疗效的比较

Comparison of effect of levofloxacin triple and bismuth quadruple in HP eradication

HPLC法测定注射用甲磺酸左氧氟沙星有关物质

Determination of related substances of levofloxacin mesylate for injection by HPLC

方法：参照国家药监局颁发的标准考察溶液颜色、pH值、有关物质及左氧氟沙星含量。

METHODS The color , pH , related substances , concentration using related standards were determined .

比较2个年份的耐药率，2008年头孢唑啉、头孢吡肟、氧氟沙星和左氧氟沙星的耐药率较2005年有显著提高（P＜0.05）。

The resistance rates to cefazolin , cefepime , ofloxacin and levofloxacin in 2008 were significantly higher that in 2005 ( P ﹤ 0.05 ) .

HPLC法测定盐酸左氧氟沙星液状眼用凝胶中左氧氟沙星的含量

HPLC determination of levofloxacin in Levofloxacin ophthalmic gel Bioequivalence of levofloxacin hydrochloride tablets in Chinese healthy volunteers

Bayesian反馈法研究左氧氟沙星在呼吸系统感染患者中药动学及药效学

Pharmacokinetics and pharmacodynamics of levofloxacin in patients with respiratory tract infections using Bayesian forecasting

结论bet法可用于检查乳酸左氧氟沙星注射液中的细菌内毒素。

Conclusion the bacteria endotoxin in levofloxacin lactate injection can be determined with bet method .

目的考察注射用盐酸左氧氟沙星与维生素C注射液、三磷酸腺苷二钠注射液、注射用辅酶A及肌苷注射液的配伍稳定性。

Aim To study the compatible stability of Levofloxacin Hydrochloeide with Vitamin C Iinjection , Adenosine Disodium Triphosphate Injection , Coenzyme A Injection and Inosine Injection .

左氧氟沙星可通过作用于细菌的脱氧核糖核酸旋转酶，抑制细菌DNA的复制和转换，发挥广谱抗菌作用。

It can affect the function of DNA gyrase in bacteria , which results in the inhibition of the duplication and transformation of DNA .

左氧氟沙星治疗COPD合并肺部感染的疗效观察

Chinical study of levofloxacin in the treatment of respiratory tract bacterial infections with COPD

目的研究不同盐的左氧氟沙星体外抗HBV的作用及其机理。

Objective Levofloxacins of various salts were studied for its effect and mechanism on hepatitis B in vitro .

莫西沙星与左氧氟沙星治疗细菌性感染的细菌学疗效比较的Meta分析

Meta-Analysis on Microbiological Outcomes of Bacterial Infections Treated with Moxifloxacin Versus Levofloxacin

左氧氟沙星治疗ICU呼吸机相关性肺炎临床观察

Levofloxacin for Patients with Ventilator Associated Pneumonia in ICU

结论左氧氟沙星的离子分布、分子荷电性质和表观分配系数均表现出强的pH值依赖性。

Conclusion The species distribution , molecular electrical property and apparent distribution coefficient of levofloxacin all demonstrated much to be reliant on pH value .

含左氧氟沙星方案治疗复治肺结核临床疗效的Meta分析

Meta-analysis on clinical efficacy of combination regimens with levofloxacin in retreatment of pulmonary tuberculosis

用琼脂稀释法测定对环丙沙星、左氧氟沙星、加替沙星的最小抑菌浓度（MinimalInhibitoryConcentration，MIC）。

The minimal inhibitory concentration ( MIC ) of ciprofloxacin , levofloxacin , gatifloxacin was measured by using agar dilution method .

结果在5%葡萄糖注射液中，乳酸左氧氟沙星注射液分别与以上7种药物配伍，其pH值、外观、紫外吸收光谱等几乎无变化。

RESULTS Levofloxacin lactate injections had no significant changes in absorbance , absorption curve , exterior appearance and pH after the addition of the above injections .

目的：探讨克林霉素或鱼腥草与左氧氟沙星联合作用对粘液型PA体外生物被膜的影响。

To investigate the influence of Houttuynia Cordata Thunb or Clindamycm combined with levofloxacin on the mucoid PA biofilm .

目的：考察盐酸左氧氟沙星在葡萄糖输液中与4种注射液（消旋山莨菪碱、地塞米松、氯化钾、维生素C）的配伍稳定性。

Objective : To study the stability of levofloxacin hydrochloride mixed with four kinds of injection ( raceanisodamine , dexamethasone , potassium chloride , vitamin C ) in glucose injection solution .

结果：在室温下8h内，乳酸左氧氟沙星与常用注射液配伍后，外观和pH值变化不显著；

Result : There were no obvious changes in the external appearance and pH value in 8 hours .

RP-HPLC法测定乳酸左氧氟沙星氯化钠注射液中主药含量及有关物质

Determination of Levofloxacin Lactate and Related Substances in Levofloxacin Lactate and Sodium Chloride Injection by RP-HPLC

体外药效学（PD）研究系测定左氧氟沙星对近期823株临床分离菌的药敏参数[最低抑菌浓度（MIC）]，并与其他相关抗菌药进行比较。

The in vitro activity MIC of levofloxacin against 823 clinical isolates were determined and compared with other antimicrobial agents .

以左氧氟沙星与四苯硼酸根形成的缔合物为电活性物质，研制了一种左氧氟沙星PVC膜涂层玻璃电极，并对其响应性能进行了系统研究。

The levofloxacin selective electrode prepared by coating the mixture of levofloxacin and sodium tetraphenylboron association complex with PVC membrane on a glass electrode is reported .

目的评价氨苄西林-舒巴坦组（A组）、头孢哌酮组（B组）、左氧氟沙星组（C组）三种方案对治疗社区获得性肺炎药物经济学成本与效果。

OBJECTIVE To evaluate the cost-effectiveness of three therapeutic schemes , ampicillin-sulbactam injection ( A ), cefoperazone injection ( B ) and levofloxacin injection ( C ) in treatment of the community acquired pneumonia infections .

结果替卡西林钠-克拉维酸钾与pH较低的左氧氟沙星、阿米卡星配伍产生沉淀，加碱性试液pH升高后，溶液变澄清。

Results Precipitate happened in the compatibility of Ticarcillin / Clavulanate acid with low pH drugs such as Levofloxacin and Amikacin . The precipitate was dissolved by adding sodium hydroxide solution .

结果：1.左氧氟沙星组与阿奇霉素组的有效率分别为93.3%和83.3%，痊愈率分别为82.2%和67.4%，差异均有统计学意义（p0.05）。

The effective rate of levofloxacin group and azithromycin group were 93.3 % and 83.3 % respectively , and the differences between two groups were statistical significance ( p0.05 ) .

因此，联用PPI是否影响左氧氟沙星胃内转运、分布尚不明确。

Therefore , whether the PPI will influence the transport and distribution of levofloxacin in stomach is not clear .

含左氧氟沙星10日序贯疗法对Hp初次根除失败的补救治疗根除幽门螺杆菌治疗对Hp相关性溃疡患者疗程的影响

Levofloxacin Based 10 Day Sequential Therapy as Rescue Therapy for Hp Infection with a Previous Failed Course The significance of eradicate helicobacter pylori on helicobacter pylori associated peptic ulcer

目的观察丁胺卡那，左氧氟沙星在耐多药肺结核（MDR-TB）治疗中的疗效。

Objective To observe the effects of levofloxacin and amikacin on multi-drug resistant pulmonary tuberculosis ( MDR-TB ) .