妊马雌酮

妊马雌酮对大鼠体外培养成骨细胞作用的研究

Effects of premarin on rat osteoblasts in vitro

结论妊马雌酮可促进成骨细胞增殖并明显提高PKC和抗凋亡蛋白Bag-1的表达量是其防治骨质疏松的机理之一。

Conclusions Premarin prevents and treats osteoporosis by promoting multiplication of osteoblasts and enhancing the expression of PKC and anti-apoptosis protein Bag-1 .

妊马雌酮能明显提高体外成骨细胞PKC的表达量和抗凋亡蛋白Bag-1的表达量。

Expression quantity of PKC and anti-apoptosis protein Bag-1 was increased remarkably .

方法选取符合条件的绝经后高胆固醇血症妇女52例，给予妊马雌酮0.625mg/d，安宫黄体酮（MPA）4mg/d治疗。

Methods 52 women with hypercholesteremia after menopause was treated with 0.625 mg / d Premarin ( conjugated estrogens ) and 4 mg / d medroxyprogesterone acetate ( MPA ) .

口服替勃龙或替勃龙加妊马雌酮对绝经后乳腺增生的影响

The Effect of Tibolone or Tibolone Plus Low Dose Premarin in Postmenopause Women with Breast Proliferation