基因剪接

真核基因剪接位点二级结构特征

Secondary structural characteristic of eukaryotic gene splicing sites

人类基因剪接供体位点识别的研究

Research of Human Gene Splicing Donor Site Recognition

延时HMM在基因剪接供体位点识别中的应用

Application of Time-delay HMM in Gene Splice Donor Sites Prediction

力生长因子（mechanogrowthfactor，MGF）是一种新发现的生长因子，由Igf-1基因剪接变异产生。该生长因子在拉伸刺激的骨骼肌或损伤的肌肉、神经等组织中表达被提高。

Mechano growth factor ( MGF ), a novel growth factor , is originated from alternative splicing of Igf-1 gene , which is mainly expressed in stretched skeletal muscle , damaged muscle and neuron .

Tra2β1蛋白在神经特异性的基因剪接中的功能

Function of tra2 β 1 proteins in the splicing of neural-specific genes

雄激素受体基因剪接受点突变G~（3346）→T引起一例完全型雄激素不敏感综合征

An acceptor splice site mutation responsible for complete androgen insensitivity syndrome

最大信息原理、能量及选择约束在基因剪接位点预测分析中应用的研究

Studies on the Application of Maximum Information Principle , Energy and Selection Constraints to the Prediction and Analysis of Splice Sites in Genes

方法特异引物PCR扩增鼠胚皮肤mRNA逆转录产物，获得septin2基因短剪接本septin2s。

Methods The short splicing fragment was obtained by amplifying the reverse transcription product of the fetal mouse skin mRNA with PCR .

同一基因的剪接变异体可有不同的功能。在胃癌方面已有数篇关于rp基因或剪接变异体表达方面的研究报道。

The alternatively splicing variants of the same gene product can function in more than one distinct capacity . There are a few literatures on the expression of ribosomal protein or alternatively splicing transcript in gastric cancer .

基因选择性剪接的生物信息学研究概况

The Application of Bioinformatics in the Research of Alternative Splicing

针对基因选择性剪接的多序列比对算法研究

Research on multiple alignments for alternative splicing

黄牛睾丸特异乳酸脱氢酶-C基因选择性剪接体的克隆与序列分析

Cloning and Sequence Analysis of Multiple Splice Variants of Lactate Dehydrogenase C in Cattle Testes

真核基因选择性剪接机理的初步研究

Alternative splicing mechanism for eukaryotic gene

真核基因可变剪接的普遍性及其在机体生理与病理过程中的重要作用，使得可变剪接的系统分析已成为功能基因组研究中的热点之一。

Since the alternative splicing of eukaryotic genes have found to be universal and play an important role in physiology and pathology , systematic analysis of alternative splicing is becoming a new hotspot of functional genome research .

脆性X综合征分子诊断方法体系的建立及其疾病基因新型可变剪接转录产物的鉴定

Establishment of Molecular Diagnostic Methods for Fragile X Syndrome and Identification of Novel Alternatively Spliced Transcripts of Its Disease Gene

鉴定9个新的RHD基因mRNA可变剪接体

Identification of Nine Novel Alternative Splicing Isoforms of RHD mRNA

MGF是Igf-1基因的选择性剪接变异体，在拉伸刺激的骨骼肌和损伤的神经、肌肉等组织中高表达。

It is an alternative splicing variant of Igf-1 gene which is mainly expressed in stretched skeletal muscle , damaged muscle and neuron .

出生后大鼠牙胚组织中nfic基因多种选择性剪接体的克隆研究

Analysis of multiple alternative spliceosome of nfic gene in postnatal rat molar tissues

激肽原基因的选择性剪接与功能研究进展

Progress in the Study on Alternative Splicing and Functions of Kininogen Genes

蝎毒液肽基因内含子剪接信号分析

Analysis of splicing signals of scorpion venom peptide introns

外力作为信号诱导基因的选择性剪接与力生长因子表达

Mechanical Signals Induced Gene Alternative Splicing and The Expression of Mechano Growth Factor

研究基因的可变剪接对理解真核生物基因调控具有十分重要的意义。

Studying alternative splicing mechanism is of great significance to understanding eukaryote gene regulation .

为对真核基因的选择性剪接形式进行准确、快速、有效的研究，提出了一种启发式多序列比对算法。

A heuristic algorithm for multiple alignment was developed to more effectively study alternative splicing patterns of eukaryotic genes .

主要的研究工作如下：一、真核基因编码区剪接位点识别算法的研究。

The central work as follows : 1 . The research on method for splice sites identification in eukaryotic gene coding regions .

我们报告了一个新基因左拼接剪接变异的证据，这个新基因是一个新发现的鼠同源基因端粒调节体。

We report the identification of a splice donor mutation in a novel gene , which is the mouse ortholog of a newly discovered telomeric regulator .

在多细胞组织不同发育阶段和不同外界环境刺激变化过程中，单个基因通过选择性剪接可以产生功能不同的蛋白，因此选择性剪接是基因表达调控的一种机制。

The alternative splicing of pre-mRNA is a fundamental mechanism of differential gene expression in terms of giving rise to functionally distinct proteins from single gene , according to the developmental and environmental stimulus states in multicellular organisms .

本文简要综述雌激素受体β的基因结构、剪接变体、转录调节机制及其在乳腺癌发生发展、治疗预后和抗雌激素耐受中的意义。

This review focused on the ER β gene structure , splicing variants , transcriptional mechanisms , and the significance of ER β expression in the carcinogenesis , development , therapy , prognosis , and antiestrogen resistant of breast cancer .

PCR一步法检测水稻蜡质基因第一内含子剪接供体+1位碱基

One-Step PCR Method for Detecting the First Base of Splice Donor of Wx Intron 1 in Rice

人类PKNOX1基因一种新剪接型全长cDNA的克隆与表达分析

Molecular Cloning for an Alternatively Splicing cDNA of HumanPKNOX_1 Gene and It 's Expression Analysis

DNA序列上核小体的准确定位在基因转录，mRNA剪接，DNA复制和DNA修复中扮演着重要的角色。

The precise positioning of nucleosomes along the DNA plays important roles in gene transcription , mRNA splicing , DNA replication and DNA repair .