吲唑

吲唑、3-卤代吲唑互变异构反应机理的理论研究

Theoretical Study on Reaction Mechanism of Tautomerization of Indazole and 3-halogeno-indazole

7-硝基吲唑对兔异丙酚麻醉深度调节的研究

Effects of 7-nitro indazole on anesthetic depths in rabbits induced by propofol

7-硝基吲唑对缺氧缺血新生大鼠海马CA1区神经元凋亡的影响

Effect of neuronal apoptosis in the hippocampal CA_1 region by 7-NI in the hypoxic-ischemic neonatal rats

含吲唑基团偶氮苯聚合物的RAFT法合成及其性能研究

Preparation of Azo Polymer Bearing Indazole Moiety via RAFT Polymerization and Investigation on Their Properties

并探讨选择性一氧化氮合酶抑制剂&7-硝基-吲唑（7-NI）对大鼠HIBD时神经元凋亡的影响。

And to evaluate the effect of selective nitric oxide synthase inhibitor-7-NItroindazole ( 7-NI ) on apoptosis of neurons after HIBD in rats .

一种新型生长物质&吲唑酯（Ethychlozate）的分析

Analysis of a new plant growth substance & ethychlozate

方法采用落体法大鼠TBI动物模型，观察大鼠TBI早期脑组织NO含量、NOS活性的动态变化和特异性nNOS抑制剂7-硝基吲唑（7-NI）对其的影响。

Methods Using rat model of focal severe cortical contusions according to Feeney , NO content and NOS activity in ipsilateral cortex , and the effect of nNOS inhibitor 7-nitroindazole ( 7-NI ) on them were observed .

结论：7-硝基吲唑通过选择性抑制中枢nNOS活性增强异丙酚麻醉效能，提示中枢NO／cGMP信号转导途径在异丙酚全麻作用机制中发挥作用。

CONCLUSION : 7-NI can increase the anesthetic action of propofol by selectively inhibition of the activity of central nNOS , indicated that central NO / cGMP signal trans-duction pathway play an important role in the general anesthesia machanism of propofol .

7硝基吲唑在缺氧缺血性脑损伤中的作用机制

Protective mechanism of 7-nitro indazole in neonatal rats with hypoxic-ischemic brain damage

新型植物生长调节剂1-甲基-3-氧乙酸吲唑的合成和应用

Synthesis and Application of a Novel Plant Growth Regulator 1-Methyl-3-O-acetic Acid Indazolone

综述了1H-吲唑-3-羧酸的合成方法，并评述了其优缺点；

Synthetic methods for 1H-indazole-3-carboxylic acid were reviewed and evaluated .

目的研究7-硝基吲唑在鼠脑局灶缺血中的保护作用。

Objective To study the protective role of7-NI on the focal cerebral ischemia in rats .

1H-吲唑-3-羧酸的合成工艺改进

Improved synthesis of 1H-indazole-3-carboxylic acid

5硝基吲唑不仅对潜影的形成有明显阻滞作用，而且对显影也有抑制作用；

5 ? nitro ? indazole had both inhibitions on the latent image formation and on the development .

7-硝基吲唑组和氨基胍组可使一氧化氮合酶活性下降，前者作用明显高于后者（P<0.05）；

The activity of NOS decreased in the aminoguanidin group and 7-NI group , and the effect in the former was higher than that in the latter ( P < 0.05 );

结果与结论该方法以55.3%的收率简单方便地制备了1H-吲唑-3-羧酸，所用起始原料及试剂的成本低、反应条件温和、易于操作，适合工业化生产。

Results and conclusion This improved synthesis with an overall yield of 55.3 % shows the advantages of lower cost of starting materials and reagents , mild reaction condition and simple operation , it is suitable for industrial manufacture .

Cu（Ⅰ）催化的分子内氨基化反应合成吲哚并[1,2-b]吲哒唑类化合物

Synthesis of indolo [ 1,2-b ] indazole derivatives via copper (ⅰ) - catalyzed intramolecular amination reaction