卡介苗
- 名BCG vaccine;Bacille Calmette-Guérin vaccine
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[BCG vaccine; Bacillus Calmette Guerin vaccine] 预防结核的一种疫苗,是法国科学家卡默特(Albert Calmette)和介兰(Camille Guérin)首先制成的
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B淋巴细胞对卡介苗颗粒性抗原的递呈作用
Antigen presentation of human B lymphocytes on BCG particulate antigen
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但浅表性膀胱癌术后复发率仍很高,术后为预防复发多配合膀胱灌注治疗,目前常用的药物为丝裂霉素C、羟基喜树碱、卡介苗等。
But the recurrence rate of superficial bladder cancer after surgery is still high .
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E组灌注肝素+3H卡介苗。
Group E : heparin and 3H - BCG instillation .
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重组卡介苗表达的MalE蛋白T细胞表位的鉴定
Identification of T cell epitopes of MalE protein expressed by recombinant Mycobacterium bovis BCG
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卡介苗菌基因组DNA对小鼠腹腔巨噬细胞激活效应的初步研究
Primary Study on the Action of Genome DNA of Mycobacterium Bovis-Bacille Calmette-Guerin for Macrophage Activation in Mice
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卡介苗ERP基因置换型打靶载体的构建
Construction of the gene targeting vector of ERP gene in BCG
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卡介苗和猪苓多糖对膀胱癌细胞TLR2/4-NF-κB信号通路的影响
Effect of BCG and Polyporus Polysaccharide on TLR2 / 4-NF - κ B Signal Pathway in Bladder Cancer Cell
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将打靶载体电穿孔入卡介苗,筛选并鉴定卡介苗ERP基因缺失突变株。
BCG mutation with deleted ERP gene was constructed .
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重组大肠杆菌E.卡介苗基因组的克隆
A recombinant E. Cloning of Bacillus Calmette-Guerin Genomic DNA
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膀胱内卡介苗灌注在Ta和T1期膀胱癌治疗中的应用
Intravesical Bacillus Calmette-Guerin in Ta and T_1 Bladder Cancer
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结果:共有16个研究符合标准被纳入,涉及总病例数1242例,其中进行卡介苗灌注治疗708例,丝裂霉素C治疗534例;
Results : 16 trials including 1242 patients were eligible to the inclusion criteria . Of these patients 708 were treated with BCG and 534 with MMC .
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方法:采用卡介苗(BCG)和细菌脂多糖(LPS)诱导小鼠发生实验免疫性肝损伤。
Method : Mouse immunological liver injury was induced by BCG and LPS .
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表浅膀胱肿瘤病人卡介苗灌注前后自然杀伤(NK)细胞水平
NK cell activities in superficial bladder cancer patients before and after treatment with BCG
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二组术后均常规行卡介苗(BCG)膀胱灌注。
Both groups received a bcg vaccine ( BCG ) routine treatment .
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成人接种卡介苗(BCG)对流感预防作用的研究
Study of Preventive Effect on Influenza in the Adult With BCG Vaccination
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经小剂量灭活卡介苗治疗0.5年后,其T淋巴细胞亚群及淋巴细胞转化率明显改善(P<0.01或P<0.05)。
But after the treatment of the small dosage inactivated BCG vaccine for half a year , these parameters of the patients were improved ( P0.01 or P0.05 ) .
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利用westernblot技术,对结核分枝杆菌和卡介苗抗原蛋白进行比较研究。
The antigen proteins of Mycobacterium tuberculosis and Bacillus Calmette Guerin ( BCG ) were studied and compared by Western Blot analysis .
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结论BCG分泌性蛋白具有较强的免疫原性,可显著激活单个核细胞功能,提示卡介苗分泌性蛋白在抗结核免疫中起了积极作用。
Conclusion BCG 's secretory protein has strong immunogenicity can activate human MCs .
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加温灭活卡介苗(BCG)对动物睾丸抑精作用的影响
Effect of inactivated BCG on spermatogenesis of rabbit testis
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采用灭活HBV全抗原卡介苗提取物治疗了158例,综合药物治疗87例。
Of these , 158 were treated with inactivated HBV pan-antigen vaccine ptus BCG extract and 87 with other drugs .
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而此时再用卡介苗感染A549细胞,细胞的抵抗能力明显下降。
BCG infection at a time then A549 cells , resistance decreased .
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方法:来用卡介苗+脂多糖(BCG+LPS)造成免疫性肝损伤模型小鼠,观察本品对血清中ALT、AST活力单位、肝脾脏器系数和肝脏病理组织学损伤程度的影响。
Method : The model of hepatic damage of immunity by BCG + LPS .
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由于卡介苗(BCG)的使用,结核病的发病率比过去有所下降。
The incidence of tuberculosis declined due to the use of BCG in the past .
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卡介苗对哮喘小鼠TH1/TH2平衡的影响
Effects of Bacillus Calmette-Guerin on T_H1 / T_H2 balance in a mouse model of asthma
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卡介苗多糖核酸对COPD缓解期患者免疫功能的影响
Effect of Amylose Nucleic Acid of BCG Vaccine on the Immunologic Function of COPD Patients in Remission Stage
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RP对卡介苗和脂多糖致免疫性肝损伤的保护作用。
RP 's immune modulation effect on mouse liver immune injure induced by BCG and LPS .
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分泌表达人IL-12基因重组卡介苗菌株的构建和筛选
Construction and Screen of Recombinant BCG Strain Expressing and Secreting Human Interleukin 12 Protein
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干扰素和卡介苗对肝癌大鼠枯否细胞释放TNF和IL-1的影响
Influence of IFN α - 2b and BCG on the releasing of TNF and IL-1 by Kupffer cells in rats with hepatoma
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结论构建了卡介苗ERP基因置换型打靶载体,并构建筛选卡介苗ERP基因缺失突变株。
Conclusion Constructing the replacement vector which is used to the gene knockout in BCG . constructing the BCG mutation with deleted ERP gene .
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目的:探讨卡介苗(BCG)对肺结核病人T淋巴细胞亚群和临床疗效的影响。
Objective : To evaluate the effect and safety of BCG vaccine on initially treated pulmonary tuberculosis .