信号跨膜转导
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因此,LOX-1如何介导信号跨膜转导的机制尚不清楚。
How LOX-1 mediates this signal transduction is still unknown .
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TLR4细菌脂多糖(li-popolysaccharide,LPS)是介导信号跨膜转导的主要受体,对于革兰氏阴性菌的感染性炎症至关重要。
Toll-like receptor 4 ( TLR4 ) is one of the major receptors which mediates the signal 's transmembrane transduction , and is of great important to the infective inflammation caused by Gram-negative bacteria .
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结论LBP抑制肽通过抑制由CD14介导的LPS信号跨膜转导和TNFα的分泌,对LPS所致疾病如脓毒血症、急性肺损伤可能有潜在的治疗作用。
Conclusion LBP inhibitory peptide might have a potential protective effect on LPS induced inflammatory disorders such as sepsis and acute lung injury through inhibiting the mRNA and protein expression of CD14 and reducing the release of TNF - α .
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此外,Mac-1还能与许多细胞膜表面的糖蛋白缔合成复合物,介导信号的跨膜转导。
It can also form a complex with many membrane glycoproteins , functioning as a signal transducing partner for them .