亚砷酸

亚砷酸诱导人低分化鼻咽癌细胞系肿瘤抑制基因表达

Up-regulation of the tumor-suppressing gene expression in nasopharyngeal carcinoma cells induced by Arsenic Trioxide

亚砷酸联合维生素C治疗难治性复发性多发性骨髓瘤

Treatment of relapsed / refractory multiple myeloma by arsenic trioxide and ascorbic acid

亚砷酸钠致脏器细胞DNA链断裂的实验研究

Study on DNA Strand Breaks in Different Organs Induced by NaAsO_2

姜黄素拮抗亚砷酸钠所致的DNA链断裂损伤

Antagonistic effect of curcumin on sodium arsenite induced DNA damage in mice

叔丁基对苯二酚对亚砷酸钠致changliver细胞毒性的影响

Antagonism of Tert-butylhydroquinone to Sodium Arsenite-Induced Cytotoxicity in Chang Liver Cells in vitro

活性氧在亚砷酸钠诱导Chang肝细胞凋亡中的作用

Reactive oxygen species play an important role in NaAsO_2-induced Chang liver cells apoptosis

叶酸对亚砷酸钠致Chang肝细胞毒性和氧化应激的影响

Effects of Folate on Sodium Arsenite-Induced Toxicity and Oxidative Stress in Chang Hepatocytes

青蒿琥酯对K562细胞凋亡诱导作用及其与亚砷酸的协同作用

Apoptosis-inducing effect of artesunate on K562 cells and its synergy with arsenious acid

免疫细胞化学法发现亚砷酸钠能显著上调细胞Caspase-3蛋白的表达。

Sodium arsenic up-regulated Caspase-3 protein expression in BGC-823 cells .

亚砷酸钠染毒对体外培养人淋巴细胞CAT及其基因表达的影响

The effects on the leave of CAT and the expression of its gene in human lymphocyte in vitro culture induced by sodium arsenic

黄磷亚砷酸钠四氯化碳肝损害LDH同工酶的比较研究

Comparison of Lactate Dehydrogenase Isoenzymes of Hepatic Injury Induced by Phosphorus , Sodium Arsenite and Carbon Tetrachloride

亚砷酸诱导肝癌Bel-7402细胞分化的研究

The differentiation of Bel - 7402 hepatocarcinoma cells induced by arsenious acid

方法采用流式细胞术、DNA电泳和免疫印迹研究测定亚砷酸对NB4细胞凋亡作用。

Methods Flow cytometry and DNA gel eletrophoresis and immunoblot were used to determine the degree of NB 4 cells apoptosis .

方法分析亚砷酸在治疗5例非霍奇金淋巴瘤（NHL）、1例多发性骨髓瘤（MM）、3例骨髓异常增生综合征（MDS）中的疗效和毒副反应。

Methods Analyzed the treatment effects and side effects in 5 cases of NHL , 1 case of MM and 3 cases of MDS .

目的：体外培养人外周血淋巴细胞，探讨不同浓度的亚砷酸钠（NaAsO2）对淋巴细胞的生物学效应及作用机制，并观察亚硒酸钠（Na2SeO3）对砷毒性的拮抗作用。

Objective : To investigate the different dose sodium arsenite ( NaAsO_2 ) on lymphocyte biological effect and function mechanism , and the antagonism effects of selenium in vitro .

本文报告了亚砷酸钠和砷酸钠对中国地鼠卵巢细胞（CHO）的毒性和细胞遗传学效应。

The cytotoxic and cytogenetic effect of sodium arsenite and sodium arsenate on Chinese hamster ovary ( CHO ) cells is reported .

亚砷酸钠还可引起CHO细胞的姐妹染色单体互换率的增加和人类淋巴细胞染色体的断裂和畸变。

Sodium arsenite was also shown to produce increased sister chromatid exchange in CEO cells and increased chromosome breakage in human lymphocytes .

亚砷酸能下调AP-1和MIP-1α表达，可能对RA有一定治疗作用。

Sodium arsenite down-regulated the expression of AP-1 and MIP-1 α and may have some therapeutic effects in RA .

亚砷酸对BXSB狼疮鼠狼疮性肾炎的治疗作用

The Therapeutically Effects of Sodium Arsenite on Lupus Nephritis of BXSB Spontaneous Lupus Mice

目的探讨亚砷酸钠对人胃癌细胞株BGC-823的作用机制。

Objective To investigate the antitumor mechanism of sodium arsenic on human gastric carcinoma cell line BGC-823 in vitro .

并通过测定硒多糖、亚砷酸钠对肝谷胱甘肽过氧化物酶（GSH－Px）和脂质过氧化（LPO）的影响，探讨了硒、砷相互作用的机理。

And the mechanism was also illuminated by determining their effects on the activity of glutathione peroxidase ( GSH Px ) and the lipid peroxidation .

卵巢癌不同证型P-gp、P53的表达及亚砷酸、托泊替康等干预的体外研究

Research on the Expressions of P-gp and P53 of Different Syndrome Types in Ovarian Cancer Together with the Vitro Research about Treatment with Arsenious Acid Injection and Topotecan

方法原代培养皮肤成纤维细胞和表皮细胞，通过直接细胞计数法和噻唑蓝（MTT）还原法检测亚砷酸钠诱导对2种细胞系生长的影响。

Methods Cell number counting , MTT reduction assay , transmission electron microscope were performed in primary cultured skin cells , and sodium arsenite was used as tester inorganic arsenics .

方法采用MTT实验测定亚砷酸钠及氟化钠对正常人淋巴细胞的LC50，然后以此为依据制定试验剂量（LC50的1/100~1/10），观察低剂量氟、砷单独及联合作用对正常人淋巴细胞增殖的影响。

Methods The MTT test is applied to this study for observing the effect on the proliferation of human lymphocytes in vitro .

随着亚砷酸浓度增加，PCNA及hTRT阳性细胞平均灰度值逐渐下降（P<005）。

The average gray level of PCNA and hTRT positive cell was decreased gradually when concentration of arsenic trioxide was increased ( P < 0.05 ) .

目的：体外观察亚砷酸钠、羟基喜树碱对人胃癌细胞株BGC-823、SGC-7901的联合效应，并探讨其作用机制。

Objective : To study the combined effect and antitumor mechanism of sodium arsenite and HCPT on human gastric carcinoma cell lines BGC-823 and SGC-7901 in vitro .

方法采用亚砷酸钠（Ars）在体外诱导ECs凋亡，应用流式细胞术测定凋亡细胞比例、细胞间黏附分子ICAM-1表达和细胞内氧化状态水平，以及NAC处理后上述指标的改变。

Methods Ars was used to induce ECs apoptosis in vitro . ECs apoptosis , ICAM-1 expression and oxidative state and their changes after NAC treatment were detected by flow cytometry .

目的观察不同剂量亚砷酸钠染毒大鼠肝细胞膜转运蛋白&多药耐药相关蛋白2（MultidrugResistance-AssociatedProtein2，MRP2）表达水平的变化及与砷代谢的关系。

Objective To explore the relationship between the expression of hepatic multidrug resistance-associated protein 2 ( MRP2 ) in rat correspondence with arsenite and arsenite metabolites .

研究了硒多糖、亚砷酸钠在体内、外对大鼠肝微粒体酶细胞色素P－450、b5、NAD（P）H－细胞色素C还原酶、谷胱甘肽硫转移酶（GST）的影响；

The effects of selenium polysaccharide and sodium arsenite on the contents of microsomal cytochrome P450 , b5 and activities of NAD ( P ) H cytochrome C reductase and glutathione S transferase in rat were studied in vivo and in vitro experiments .

其中以IAA抑制红细胞的乳酸生成和氧耗的效应最强，NaF次之，亚砷酸盐最弱。

The inhibition of lactic acid production and oxygen consumption was the strongest in the case of iodoacetic acid ( IAA ), with sodium fluoride ( NaF ) ranking next , and arsenite third .