vinculin

Studies on vinculin and its binding with actin filaments and lipids in vitro

纽带蛋白及其与微丝和膜结合的研究

Focal adhesion kinase ( FAK ) and vinculin expression were evaluated using immunofluorescence staining .

肌动蛋白，局部黏附激酶及纽带蛋白的表达采用免疫荧光染色观察。

Image analysis also showed that the expression of vinculin increased with the growth of neurons .

图像分析结果表示，随神经元的分化成熟，vinculin的表达量呈逐渐增加趋势。

Role of Vinculin in Cell Response to Mechanical Stimuli

Vinculin在细胞响应力学刺激中的作用

Three-dimensional distributions and significance of vinculin in nerve growth cones

钮蛋白在神经生长锥的三维分布及其机能意义

Mechanisms of Stress Fiber , Vinculin and FAK on Hepatic Fibrosis in Rats

应力纤维、纽蛋白和粘着斑激酶对大鼠肝纤维化作用机制的研究

Expression of Vinculin in Stomach Intraepithelial Neoplasia and Clinical Significance

纽蛋白在胃上皮内瘤变的表达及临床意义

The cell adhesion was detected by the expression of vinculin by means of indirect immunofluorescence .

用间接免疫荧光法检测Lp（a）对HMC上黏附蛋白表达的影响。

Objective To study the mechanism of vinculin in the process of nerve growing and morphologic changes of nerve growth cones .

目的探索钮蛋白（vinculin）在神经生长锥形态变化和神经生长过程中的作用机制。

In the longitudinal direction , vinculin mostly distributed in the free surface side , but not in the matrix side .

在纵轴方向，vinculin主要分布在中部以上的表面游离侧，基质侧未见分布；

Changes of integrin β _3 , paxillin and vinculin in vascular smooth muscle cells in response to stress

压力诱导血管平滑肌细胞整合素β3、桩蛋白和纽蛋白的变化

It means the expression of vinculin was correlated to carcinogenesis 、 invasion and metastasis in esophageal squamous carcinoma .

这表明，vinculin表达与食管癌的癌变、浸润及转移有关。

Vinculin is a kind of cytoskeletal proteins .

纽蛋白（vinculin）是一种细胞骨架蛋白。

MALDI-TOF MS analysis and NCBI database searching demonstrated them as vinculin and mitochondrial aconitase , respectively .

通过质谱分析和数据库检索，鉴定为纽蛋白和线粒体顺乌头酸酶。

Conclusion Vinculin and mitochondrial aconitase may be involved in the cytotoxicity , which may be the target of neuroprotective drugs .

结论：纽蛋白和线粒体顺乌头酸酶参与细胞损伤，可能成为神经防护药物作用的靶点。

Interactions between purified vinculin and actin were studied by means of low shear viscometry with the falling ball viscometer and electron microscopy .

用落球粘度计测量低剪切粘度的方法研究了纽带蛋白-肌动蛋白的相互作用。

Objective To investigate the effect of pressure on distribution and expression of integrin β 3 , paxillin and vinculin in vascular smooth muscle cells of carotid common artery of rats .

目的研究压力对大鼠颈总动脉血管平滑肌细胞整合素β3、桩蛋白和纽蛋白的分布与表达的影响，探讨它们在血管平滑肌细胞的机械应力信号转导中的作用。

Conclusion These results suggest that the expression of actin is positively related to the maturity of the neurons , and works in coordination with vinculin in cultured cortical stem cells during directional differentiation into neurons .

结论本研究揭示在大脑皮层神经干细胞定向分化为神经元过程中，actin表达变化与神经元发育成熟呈正相关，且actin与vinculin共存。

Dominant-negative Effects of the Deletion of the Potenial Vinculin Binding Site in Sarcomeric - α - actinin in Cultured Chick Skeletal Myotubes : Formation of Hypertrophied Nemaline-like Bodies

肌肉型α-辅肌动蛋白的纽蛋白结合位点的缺失在培养的鸡骨骼肌管内的显性-阴性效应：肥厚性杆状体类似结构的形成

Results In fibronectin attached cells , the wild type IL 1 receptor fusion protein and vinculin were co located at focal adhesions in cell membrane . Further , the fusion proteins moved into cytoplasm and finally concentrated in nucleus after IL 1 stimulation .

结果转染了重组型IL1R1质粒的细胞生长在纤维粘连蛋白上，表达的受体融合蛋白与Vinculin位于细胞膜的焦点附着斑，用IL1β刺激可致受体转位至细胞内。

Results In the horizontal direction , the immunoactivity of vinculin and F-actin partly overlapped in the C-domain and P-domain . The strongest immunologic reactions of them occurred in the head of P-domain stretching area and filopodia .

结果在三维的水平面上，vinculin与Factin的免疫反应活性在P领域和C领域的部分区域重合，在P领域伸展方向前端和丝状伪足内免疫反应活性最强。