qns

Besides five QNs were directly coupled to BSA and OVA by active ester method .

再利用活化酯法将五种喹诺酮药物直接与BSA和OVA偶联。

The results show that the handling and stability of vehicle during braking can be improved with QNS reference model .

分别用这两种参考模型进行车辆制动时运动参数变化的仿真试验，试验表明准中性转向参考模型可以提高车辆制动时的操纵稳定性。

So , QNs has been restricted to the application to the children 、 teenagers 、 pregnant woman and lactation women .

从而限制了该类药物在儿童、青少年、孕妇、哺乳期妇女中的应用。

However , it is still unknown that which death way QNs cause injuries of chondrocytes by , whether the injuries is mediated by β 1 integrin receptor and which signaling pathways are involved .

但是QNs是以什么方式致关节软骨细胞损伤，其损伤是否通过β1整合素介导，以及与β1整合素介导的哪些信号通路有关，目前还不清楚。

The hypothesis generally accepted : QNs affect the expression or function of β 1 integrin by competing to binding to the Mg2 + of ectocellular , so that the chondrocytes are injured .

普遍被接受的假设是：QNs通过与软骨细胞表面重要受体β1整合素竞争结合胞外镁离子而影响β1整合素的表达或功能从而致软骨细胞损伤。