helf

P21 gene were integrated into the genome DNA of HELF cells by DNA recombination technique to make cell-aging model in the experiments in vitro . This cell-aging model was interfered by TP .

体外实验用基因重组技术将p21基因整合到人胚肺成纤维细胞基因组中，建立细胞衰老模型，并用银耳多糖对此进行干预；

Comparison between STO cells and hELF used as feeder layers of embryonic germ cells

以STO细胞和hELF作为胚胎生殖细胞培养饲养层的比较

Mitotic checkpoint function of HELF cells transfected with mutant gene

转染突变基因对HELF细胞有丝分裂的影响

( CONCLUSION : ) HELF as feeder layers is better than STO cells in culturing EG cells .

结论：在培养人EG细胞时，hELF饲养层较STO细胞饲养层更有优势。

Differential proteomic analysis of human normal lung cell HELF , lung adenocarinoma cell line A549 and A549 transduced RAR β gene

正常人胚肺HELF、人肺腺癌细胞A549和转染RARβ表达载体的A549蛋白质组差异分析

Conclusion ATRA could block B ( a ) P-induced cell cycle promotion through cyclin D1 / E2F-1 pathway in HELF .

结论ATRA通过cyClinD1/E2F1途径阻断苯并（a）芘诱导的HELF的细胞周期改变。

Objective : Oxidative stress effect induced by cooking oil fume volatile organic compounds ( COF VOCs ) was studied on human embryonic diploid lung fibroblasts ( HELF ) .

目的：探讨烹调油烟挥发性有机物对人胚肺成纤维细胞（HELF）的氧化应激效应。

Conclusion HSPGs probably influence the expression of HLA - I on the surface of HCMV infected HELF . HSPGs indirectly regulate the HCMV immune surveillance evasion .

结论HSPGs可能参与影响HLA-I在HCMV感染的HELF细胞表面上的表达，对HCMV逃避宿主的免疫监视起间接调节作用。

Objective To investigate the relationship between the hormesis of proliferation and oxidative stress induced by sodium arsenite ( Na_2AsO_2 ) in human embryo lung fibroblasts ( HELF ) .

目的探讨亚砷酸钠（Na2AsO2）所致人胚肺成纤维细胞（HELF）增殖兴奋效应与氧化应激的关系。

Conclusion ERK and JNK , but not p38 , mediated benzo ( a ) pyrene-induced cell cycle changes by AP-1 transactivation in HELF .

结论ERK和JNK通过活化AP-1介导B（a）P诱导的细胞周期改变；而B（a）P诱导的AP-1活力增强及细胞周期改变与p38无关。

After HELF prepared by heparin or sodium chlorate was infected by UV-HCMV , the expression of HLA-I on the surface of UV-HCMV infected HELF group was decreased .

肝素和氯酸钠干预HELF细胞后再用UV-HCMV感染的HELF细胞，其表面HLA-I的表达低于UV-HCMV组。

Objective To construct a recombinant eukaryotic vector bearing the fusion gene of human LIF gene and EGFP ( enhanced green fluorescent protein ), and to transfect it into human embryonic lung fibroblasts ( hELF ) .

目的：构建携带人LIF基因与增强型绿色荧光蛋白（EGFP）的融合表达载体，并转染人胚肺成纤维细胞，为研究LIF在维持人胚胎生殖细胞自我更新中的作用机制奠定基础。

Objective To observe the expression of HO-1 , MT1A , MT2A in human embryonic lung fibroblasts ( HELF ) induced by supernatant of alveolar macrophage ( AM ) exposed to silica .

目的观察染尘巨噬细胞上清液对人胚肺成纤维细胞（HELF）血红素氧合酶-1（HO-1）、金属硫蛋白（MT）表达的影响。

Conclusion The sodium arsenite can induce the hormesis of proliferation in HELF with the dose-effect relation of an inverted U curve . The mechanisms probably relates to different levels of oxidative stress induced by sodium arsenite of different concentrations .

结论Na2AsO2可引起HELF细胞增殖明显兴奋效应，其剂量-反应关系呈倒U形曲线，其机制可能与不同浓度Na2AsO2引起HELF细胞不同程度的氧化应激有关。