cya

Study on solubilization of CyA by using sodium cholate / lecithin mixed micelles

胆酸钠/磷脂混合胶团对环孢素A的增溶作用研究

The Inhibitory Effects of CyA on T Cell Activation and the up - regulatory Effect of Exogenous IL-2 in the Process

环孢菌素A对T细胞激活的抑制及IL-2的调节作用

CyA whole blood samples of rats and rabbits were determined by the modified method .

并用该法测定了大鼠和家兔的血药浓度。

10 patients developed World Health Organisation Score ( WHO ) grade 2 – 3 toxicity to CyA .

10例患者出现2～3级（WHO评分）的环胞霉素A毒性反应。

Cyclosporine A ( CyA ) is widely administered in the dosage forms of soft capsules , oral solutions and injections nowadays .

环孢素A（CyclosporineA，CyA）目前上市的主要剂型为软胶囊、口服溶液剂和注射剂。

Our results suggest that the inhibitory effect of CyA on T cell proliferation is most probably mediated by blocking IL-2 production as well as Tac expression .

本研究提示：降低IL-2受体的表达和抑制IL-2的分泌很可能是CyA增殖抑制的作用基础。

Results showed that nearly 80 % of CyA was released from ART within 30 min in water and had comparability in vitro release behavior to reference capsules .

结果显示，30min内，约80%的CyA自ART中溶出，与市售软胶囊的体外释放曲线有一定可比性。

Improving the ocular bioavailability of poorly water-soluble Cyclosporine A ( CyA ) to reduce toxicity and side effect was considered as main focus of this paper .

本文以增加难溶性的环状大分子环孢素A的眼部生物利用度、减少毒副作用为主体思路，进行了一系列的研究。

On the other hand , someone as old as24 can be incarcerated as a juvenile in the CYA .

另一方面，24岁的人也可能被关进加州青少年管教所。

CyA 20 mg / kg can destroy the cell structures of the seminiferous and induce the cell denaturation of zones of adrenal cortex .

CyA20mg／kg可引起生精上皮，精子及肾上腺皮质细胞结构改变。

With the further study on the function mechanism of cya and crp , the association between the two genes and virulence factors will also become a hot topic in the future research .

鉴于cya、crp基因的重要作用，其与致病因子的关系必然成为近来研究的一个热点。

Using transmission electron microscopy we have explored the toxicity action of various doses of cyclosporin A ( CyA ) on testes and adrenals of rats .

用透射电镜对不同治疗剂量环孢素A（CyclosporinA，CyA）对大鼠睾丸及肾上腺的作用进行了现实。

Preparation of ZnO by sol-gel method and its spectrographic analysis A novel solid lipid nanoparticles loaded in situ gel for CyA delivery and its lacrimal pharmacokinetics in rabbit tears

凝胶法制备纳米氧化锌颗粒及其光谱分析环孢素A纳米粒-凝胶制剂的制备及兔泪液药动学

HPLC method was developed to determine CyA in blood and tissues . The recoveries were all over 72 % , and the intra – and inter – day precision values were less than 15 % .

小鼠血液及组织中CyA含量HPLC测定方法的回收率均大于72%，日内、日间精密度良好，该方法符合生物样品分析的要求。

The CYA can accept juveniles younger than age12 after a review by the CYA Director , however , these offenders generally are kept in the community under county probation supervision .

加州青少年管教所也接受12岁以下的违法者，但通常他们是在社区的监管之下。

Conclusions Subcutaneous injection of donor specific BM combined with a shortterm intaking of CyA can induce a temporary tolerance to the allograft and also prolong the averge survival time of it ;

结论在该小鼠皮肤移植模型中，供体骨髓细胞皮下注射加短期免疫抑制剂CyA诱导出了受体对同种皮肤移植物暂时性的耐受，延长了移植物平均存活时间；

A novel solid lipid nanoparticles loaded in situ gel for CyA delivery and its lacrimal pharmacokinetics in rabbit tears ( botany ) of or relating to or characterized by spores produced by basidia .

环孢素A纳米粒-凝胶制剂的制备及兔泪液药动学（植物学）属于、有关或具有由担子孢子制造出的孢子特征。

The initial dosage of CyA was 5mg / kg / d , and then it was adjusted according to blood concentrations of CyA which were maintained to the range of 200 ng ~ 400 ng / ml.

CyA初始剂量为5mg/kg/d，然后根据血药浓度调整剂量，使其维持在200ng～400ng/ml。

To observe the clinical effect of cyclosporine A ( CyA ) treatment for focal segmental glomerulus sclerosis ( FSGS ) clinically presenting as nephrotic syndrome in children , 11 nephrotic children with FSGS , aged from 2 to 11 years , were planned to received CyA treatment .

为了观察环孢霉素A（CyA）对以肾病综合征为表现的局灶节段性肾小球硬化（FSGS）的疗效。对11例病儿进行治疗，年龄2岁～11岁。