Non-coding RNA

Organism Development Related Non-Coding RNA and Their Functional Mechanisms

与生物体发育相关的非编码RNA及其作用机理

Non-coding RNA is an important biomolecule with various regulation functions .

非编码RNA是一类重要的具有多种调控功能的生物大分子。

Identification of the non-coding RNA in the cell line derived from lung cancer with different transferring ability

不同转移能力肺癌细胞株差异非编码RNA的鉴定

Like the proteins , non-coding RNA must fold into 3D structure in order to perform different functions .

跟蛋白质一样，非编码RNA分子必须从一级序列折叠成为具有三维空间构象的结构才能发挥其相应的功能。

Molecular Mechanism of X - chromosome Inactivation Mediated By Non-coding RNA Xist

非编码RNAXist调节X染色体失活的分子机制

Alignment and Prediction of Multi-objective Optimized Non-coding RNA

多目标优化的非编码RNA比对及预测

These works will help us better understand the folding / unfolding progress and regulation mechanisms of non-coding RNA .

此项工作有助于深入了解非编码RNA分子的折叠/去折叠过程以及调控机制。

MicroRNA is an important class of non-coding RNA , and is closely associated with the development of human diseases .

MicroRNA是一类重要的非编码RNA，它的异常能导致人类疾病的发生、发展。

MicroRNA ( miRNA ) are family of small , non-coding RNA .

miRNA（microRNA）是一类长约22个核苷酸的小分子非编码RNA。

MicroRNA ( miRNA ) are family of small , non-coding RNA that can regulate expression of other genes .

在多细胞生物的基因组中都存在一类非编码RNA基因，能够产生长度约为22个核苷酸的小分子RNA，称为mi鄄croRNA（miRNA），具有调节其他基因表达活性的功能。

The study found , non-coding RNA in organisms plays an important role : regulation of gene expression , participation in the RNA shear and modification .

已有的研究发现，非编码RNA在生物体内发挥着重要作用：调控基因表达，参与RNA的剪切和修饰等。

MicroRNAs ( miRNAs ) are a set of small single stranded non-coding RNA molecules that serve as important negative gene regulators .

MicroRNAs（miRNAs）是一组小的单链非编码RNA分子，是重要的基因负调控因子。

MiRNA is a group of recently discovered , small , non-coding RNA , which down-regulate gene expression at the post-transcriptional level .

miRNA是近年来新发现的一类在转录后水平下调基因表达的小分子非编码RNA家族。

MicroRNA , one of the small molecular RNA family , is a very small section of non-coding RNA sequence , which can regulate several biological processes .

小分子RNA家族中的一员µRNA，是一段非常短的非编码RNA序列，对多种生物学过程起调控作用。

Some miRNA , which is non-coding RNA , was already confirmed to participate in the regulation of cellular network , for example , cell cycle network .

一些非编码的miRNA已经被确认能够参与细胞网络中的调控，例如细胞周期网络。

MicroRNAs ( miRNAs ) are a class of endogenous expression of small molecule non-coding RNA which could modulate posttranscriptional gene expression , has become a research hotspot .

MicroRNAs（miRNAs）是一类内源性表达的小分子非编码RNA，能够在转录后水平调控基因的表达，已成为当前研究的热点。

SRNA ( small RNA ), also called ncRNA ( non-coding RNA ), are widespread in variety of organisms , ranging from eukaryotes to prokaryotes .

sRNA（小RNA）又叫ncRNA（非编码RNA），广泛分布于原核生物和真核生物。

As the ENCODE project is done gradually , complex scattered regulatory sequences of the genomes , a large number of non-coding RNA genes and conservative elements of non-coding regions are found .

随着ENCODE计划的逐步深入，基因组复杂的散在调控序列，大量的非编码RNA基因以及非编码区域的保守元件浮出水面。

Here , we provided a new perspective to further understand the mechanisms of DNA damage and repair pathways by analyzing the potential functions of the tandem repeats and non-coding RNA located in the genome of D.

本论文通过对耐辐射球菌中串联重复序列和非编码RNA的生物信息学研究，试图从新的角度来理解耐辐射球菌的DNA损伤修复机理。

Since we entered the 21st Century , the research on non-coding RNA has been voted consecutively as top ten scientific breakthroughs for several years , and it won the Nobel Prize in Physiology or Medicine in 2006 .

步入21世纪以来，非编码RNA的相关研究连续获得Science评选的年度十大科学突破，并在2006年获得了诺贝尔生理学或医学奖。

Objective : MiRNAs are a group of highly conserved non-coding RNA and control hundreds of target genes by inhibiting translation , regulating mRNA splicing , promoting mRNA degradation and other measures . Therefore , they play an important role in tumor development .

目的：miRNAs是一类高度保守的非编码RNA，通过抑制翻译，控制mRNA剪切，促进mRNA降解等手段调控成百个靶基因，在肿瘤的发生发展中都扮演着重要角色。

In this thesis , we first perform a series of tests and comparison of different force fields and solvation models for the simulation of RNA . After that , we investigate a class of non-coding RNA with various regulation functions & riboswitch through molecular dynamic simulations .

本论文在对分子动力学模拟研究中力场参数和溶剂模型的选择做出比较评估的基础上，对一类具有多种调控功能的非编码RNA分子&核糖开关，进行了深入细致的模拟研究。

Diversity of Endogenous Non-Coding Small RNA from Rice

水稻内源非编码小RNA的多样性

MicroRNA ( miRNA ) is evolutionarily conserved , non-coding small RNA ( 19-25 nt ) involved in post-transcriptional gene regulation .

microRNA（miRNA）是一组在进化上高度保守、非编码蛋白、参与转录后调节的小分子RNA（19-25核苷酸）。

MiRNAs are a class of about 22 nucleotides ( nt ) endogenous , non-coding single-stranded RNA molecules , they are widely present in from plants , nematodes to human cells .

miRNAs是一类长约22个核苷酸（nt）的内源性的、非编码的单链RNA分子，它们广泛存在于从植物、线虫到人类的细胞中。

MiRNA is a class of about 22 nt conserved non-coding small RNA with the regulatory function , playing an important role in the regulation of developmental timing , cell proliferation and apoptosis as well as tumor development .

miRNA是一类长约22nt具有调节功能的保守的非编码小RNA，在调控发育时序，细胞增殖与凋亡以及肿瘤发生中起着重要的作用。