ENU

Preliminary Study of Mice Mutation Induced by ENU

乙酰基亚硝基脲诱导小鼠突变的初步研究

Using ENU mutagenesis we have identified a mouse model resembling human maple syrup urine disease .

突变鼠方面，已建立了一个与人类枫糖浆尿毒症相似的小鼠动物模式。

ENU administration had no significant effects on the prostate of Bama miniature pigs .

ENU给药对巴马香猪前列腺无明显影响。

On neu ( enu ) coordinate system

关于NEU（ENU）坐标系统

Studies on gene mutation and micronucleus formation induced by ethylnitrosourea ( ENU ) in transgenic mice in vivo

乙基亚硝基脲诱发转基因小鼠体内基因突变及微核形成

In this paper , two new scant hair mice were obtained by ENU inducing and mutant genes were mapped on chromosome .

本文即用ENU诱变获得了两例新的稀毛小鼠并对突变基因进行了染色体定位。本论文的工作由三部分组成。

Objective In order to accumulate basis data on short-tail mutant mice induced using N-ethyl-N-nitrosourea ( ENU ), their biological characteristics were studied .

目的研究ENU诱变手段获得的1种短尾突变小鼠的生物学特性，为相关研究提供基础数据资料。

The mortality of Bama miniature pigs gradually increased with the increase in the administration dosage of ENU , and the fertility gradually decreased .

随ENU给药剂量的增加，巴马香猪的死亡率逐渐升高，可育率逐渐降低。结果表明，巴马香猪对85mg/kg及以下剂量可耐受。

Objective To determine whether N-ethyl-N-nitrosourea ( ENU ) can induce DNA damage and may have an adverse effect on the expression of P53 and P21 in the primary cultured astrocytes .

目的研究乙基亚硝基脲（N-ethyl-N-nitrosourea熏ENU）诱发原代大鼠脑星形神经胶质细胞DNA损伤及对P53、P21蛋白表达的影响。

The food intake of Bama miniature pigs may be significantly affected during the administration with ENU , the decrease in food intake was dose-dependent , and the recovery time for food intake increased with the increase in the dosage .

ENU给药期间巴马香猪采食量会受到较大影响，采食量的减少具有浓度依赖性，采食量恢复时间随剂量的增加而延长。

One day after plating , the cells were exposed for 2 h to various doses of ethylnitrosourea ( ENU ) . CAs and SCEs were examined by the standard methods , while CT was determined by cell counts .

接种细胞一天后，用不同剂量乙基亚硝基脲（ENU）处理2小时，然后用标准法检查其染色体畸变和SCE率，用细胞计数法测定细胞毒性。