鞘磷脂

本文用FT－Raman光谱研究了东莨菪碱和神经鞘磷脂的相互作用。

The interaction of scopolamine with sphingomyelin was investigated by FT Raman spectroscopy .

FT-Raman光谱研究东莨菪碱和神经鞘磷脂的作用

FT Raman Spectroscopic Study of the Interaction of Scopolamine with Sphingomyelin

方法分离猪血细胞，用溶血，脱水，干燥等方法提取鞘磷脂，并用磷脂酶C降解鞘磷脂成神经酰胺。

METHOD Sphingomyelin was prepared through the process of separating erythrocyte from blood , erythrocytolysis , dehydration , dry , et al , and then hydrolyzed to ceramide by phospholipase C.

酸性鞘磷脂水解酶和MAPK信号通路在UVA诱导细胞凋亡中的作用

Role of Acid Sphingomyelinase and MAPK Signaling Pathway in UVA-induced Apoptosis

脂微区为近年发现的广泛存在于质膜，主要由糖鞘脂、鞘磷脂、胆固醇及多GPI锚联蛋白组成的局限性结构域。

Membrane lipid microdomain is a newly discovered membrane confined domain which consists of sphingomyelin , cholesterol , glycosphingolipid and many GPI anchored proteins .

DOPC，DOPE和神经酰胺对鞘磷脂/胆固醇双层膜结构的影响

Influence of DOPC , DOPE and Ceramide on the Organization of Sphingomyelin / Cholesterol Bilayers

在细胞表面，GPI锚定蛋白常与鞘脂（包括鞘糖脂和鞘磷脂），胆固醇等聚集在一起形成具有特定结构和功能的质膜微区，称GPI微域（GPImicrodomain）。

GPI-anchored proteins often gather with sphingolipids ( including sphingomyelin and glycosphingolipid ) and cholesterol to form special plasma membrane microdomains ( GPI microdomain ) .

微生物来源酸性鞘磷脂酶抑制剂NF-0265A的研究

NF-0265A , an acid sphingomyelinase inhibitor from metabolites of microorganisms

急性缺氧时，肺泡冲洗液中溶血卵磷脂、神经鞘磷脂、磷脂酰乙醇胺及磷脂酰甘油均下降（p0.05）；间断适应性缺氧后，基本回复到缺氧前水平。

On analysis of phospho-lipids in pulmonary surfactant of rabbits exposed to different hypoxic conditions ( simulated altitude 5 000m ), it was found that lysophosphatidylcholine , sphingomyelin , phosphatidylethanolamine and phosphatidylglycerol were decreased ( p0.05 ) by acute hypoxia and raised by adaptive hypoxia in lung lavage .

对哺乳动物的ORPs功能研究显示ORPs在有很多方面都起作用：固醇和鞘磷脂代谢的整合，固醇运输，中性脂代谢的调节，微管依赖性内涵体／溶酶体运动的调控以及信号级联的调节。

Functional studies on mammalian ORPs point in different directions : integration of sterol and sphingomyelin metabolism , sterol transport , regulation of neutral lipid metabolism , control of the microtubule-dependent motility of endosomes / lysosomes , and regulation of signaling cascades .

鞘磷脂酶活性在诱癌过程中无显著改变；

The activity of sphingomyelinase had no change during the hepatocarcinogenesis ;

用鞘磷脂作为标志分子鉴定脂筏

Sphingomyelin Can Be Used as Specific Marker for Identifying Lipid Raft

神经鞘磷脂作为第二信使也参与此过程。

SM may be a second messenger involved in this process .

结论用此法可将红细胞膜中的鞘磷脂降解成神经酰胺。

CONCLUSION Sphingomyelin can be obtained from erythrocyte membrane by this method .

实验性甲低大鼠脑鞘磷脂与脑发育关系的研究

Research of SM and development of the brain in experiment hypothyroidism rats

目的从微生物代谢物中筛选中性鞘磷脂酶抑制剂。

OBJECTIVE To screen neutral sphingomyelinase inhibitors from the metabolites of microorganism .

酸性鞘磷脂酶活化在微波辐照致神经细胞凋亡中的作用研究

Roles of acid sphingomyelinase activation in neuronal cells apoptosis induced by microwave irradiation

鞘磷脂水解产物对结肠癌细胞中碱性鞘磷脂酶的影响

Effect of Sphingomyelin Hydrolysates on Alkaline Sphingomyelinase Expression in Human Cancer HT-29 Cell

猪血红细胞膜中鞘磷脂降解成神经酰胺的实验研究

Study on the hydrolyzation of the sphingomyelin from pig erythrocyte membrane to ceramide

目的从红细胞膜中提取鞘磷脂并降解成神经酰胺。

OBJECTIVE To extract the sphingomyelin from erythrocyte membrane and hydrolyze it to ceramide .

例如神经鞘磷脂可被划分为磷脂，因为存在磷酸脂。

For example , the sphingomyelins can be classed as phospholipids because of the presence of phosphate .

鞘磷脂途径是一普遍存在的信号系统。神经酰胺在该途径中起第二信使分子作用。

The sphingomyelin pathway is a ubiquitous signaling system , in which ceramide acts as a second messenger .

TDx-FLMⅡ和卵磷脂鞘磷脂比预测胎儿肺成熟的比较

Comparison of the TDx - FLM II and lecithin to sphingomyelin ratio assays in predicting fetal lung maturity

这些结果显示了细胞内甘油磷脂和鞘磷脂信号途径之间存在的精细调控作用。

These results indicated the existence of a subtle intertwined regulatory interaction between intracellular phosphoglycerol lipids and sphingolipids signaling pathways .

相反，鞘磷脂酶则能显著增强分泌型磷脂酶A对细胞的毒性作用。

Conversely , the intracellular sphingomyelinase ( SMase ) can greatly enhance the cell death inducing effects of sPLA 2 .

5′-三磷酸腺苷（5′-ATP）作为核苷类衍生物在体内参与磷脂类（卵磷脂，脑磷脂，丝氨酸磷脂、鞘磷脂等）的生物合成。

5 ' - Adenosine triphosphate is used to synthesizephosphatidate ( phosphatidylcholine , phosphatidylserine , phosphatidylserine , phosphatidylethanolamine , etc ) .

鞘磷脂类物质不仅是真核细胞膜的重要组成部分，也是细胞与外界环境之间重要的动态调节因子。

Sphingolipids are ubiquitous , essential components of eukaryotic membranes and function as the dynamically signal factors between cells and the outer surroundings .

脊髓挤压损伤经常导致鞘磷脂的丢失，破坏了神经元传递信号的能力。

Spinal " crush " injuries often cause a loss of myelin , and so destroy the capacity of nerves to transmit signals .

脂筏的刚性有赖于附着在鞘磷脂的直链周围的胆固醇分子。

Rafts rigidity ( is ) caused by the tight parking of cholesterol molecules against the straight single lipid ( sphingolipids ) hydrocarbon chain .

鞘脂储存类疾病，如泰萨二氏病、脑苷脂沉积病和神经鞘磷脂沉积病，都涉及到连接神经细胞的凸起的多余生长和分叉。

The sphingolipid-storage diseases , Tay-Sachs , Gaucher 's and Niemann-Pick , all involve extra growth and branching of the protuberances that connect nerve cells together .