甲状腺功能减退

TSH受体基因突变致先天性甲状腺功能减退症一例及其家系分析

A study on TSH receptor gene mutations in one child with congenital hypothyroidism and analysis of the pedigree

甲状腺功能减退对新生早期大鼠各脑区甲状腺激素受体mRNA表达的影响

Effects of hypothyroidism on expression of thyroid hormone receptor mRNA during rat cerebral development

青春前期儿童甲状腺功能减退致垂体增生的MRI表现

MRI Manifestations of Children in Puberty with Pituitary Hyperplasia due to Hypothyroidism

原发性甲状腺功能减退导致垂体增生的MRI研究

MRI of Pituitary Hyperplasia in Primary Hypothyroidism

方法测定健康对照组（A组）、甲状腺功能减退组（B组）两组研究对象的跟骨超声骨参数。

Methods Calcaneal quantitative ultrasonography was performed in young female healthy controls ( group A ), patients with hypothyroidism ( group B ) .

提示，甲状腺功能减退是AMI发生机制之一。

It suggested that hypothyroidism could be one of the mechanisms of AMI .

碘摄入不足可以引起碘缺乏疾病（iodinedeficiencydisorders，IDD）&甲状腺功能减退症和大脑发育障碍。

Iodine deficiency can cause iodine deficiency disorders ( IDD ) - hypothyroidism and mental impairment .

严重甲状腺功能减退致长QT综合征一例

A case of long QT syndrome induced by hypothyroidism

孤立性TSH缺乏所致垂体性甲状腺功能减退症一例

Pituitary hypothyroidism caused by isolated TSH deficiency : one case report

目的探讨重症肌无力（Myastheniagravis，MG）与原发性甲状腺功能减退两病并存的临床特点、发病机制和治疗方法。

Objective To study the clinical characterisitics , pathogenesis and therapy of myasthenia gravis concomitant with primary hypothyroidism .

碘缺乏、甲状腺功能减退大鼠仔鼠海马c-fos、c-jun蛋白的表达

Expression of c-fos and c-jun in developing hippocampus of iodine deficiency and hypothyroid rat offsprings

如果TSH水平升高而T4水平正常，诊断为亚临床甲状腺功能减退症。

If TSH is high and the T4 is normal , the diagnosis is subclinical hypothyroidism .

继发性甲状腺功能减退症（甲减）是131I治疗甲状腺功能亢进症（甲亢）后最重要的并发症。

The secondary hypothyroidism is the most important intercurrent disease after radioiodine therapy .

NIS基因突变是导致先天性甲状腺功能减退症的原因之一。

The mutation of NIS gene may be one of the main causes of congenital hypothyroidism .

CDFI结合3DCPA诊断亚临床甲状腺功能减退症的临床应用研究

Clinical Study on Diagnosis of Sub-hypothyroidism with CDFI Combined with 3DCPA

先天性甲状腺功能减退患儿的神经发育结果：首次T4剂量和达到T4、TSH目标剂量时所需时间的比较

Neurodevelopmental outcomes in congenital hypothyroidism : Comparison of initial T4 dose and time to reach target T4 and TSH

一名FSH受体正常患者继发于原发性甲状腺功能减退症的Cullen征和巨型卵巢肥大

Cullen 's sign and massive ovarian enlargement secondary to primary hypothyroidism in a patient with a normal FSH receptor

结论碘缺乏、甲状腺功能减退可损害仔鼠在体海马LTP的诱导。

Conclusion Iodine deficiency and hypothyroidism of mother rat ma impair the induction of LTP in vivo of their pups .

碘缺乏及甲状腺功能减退子代大鼠海马长时突触可塑性与PKC活性及GAP-43表达的实验研究

Experimental Study of Long-term Synaptic Plasticity and PKC Activity and GAP-43 Expression in the Hippocampus of Iodine Deficient and Hypothyroid Pup Rats

21.3%的特发性GHD合并中枢性甲状腺功能减退。

Furthermore 21.3 % of idiopathic GHD were also complicated with apparent central hypothyroidism .

针对不同的个体，采用不同的剂量治疗才可以提高131I治疗的效率，降低甲状腺功能减退症的发病率。

Coinciding every patient with individual dose can improve the effect of radio-therapy , lower the incidence of hypothyroidism .

结论：亚临床甲状腺功能减退症是CHD多支病变的危险因素之一。血管亚临床病变的无创评估及其临床意义

Conclusion : Subclinical hypothyroidism is one of the risk factors for the multi-vessel coronary artery stenosis of CAD . Noninvasive Methods to Estimate Artery Sub-clinical Dysfunction and Its Clinical Use

其中，首次131I治疗后半年随访为甲状腺功能减退症（简称甲减）者25例，占17.6%。

Among all patients , hypothyroidism was observed from 25 ( 17.6 % ), 6 months after the first 131I therapy .

目的研究连云港地区新生儿筛查疾病&先天性甲状腺功能减退症（CH）和苯丙酮尿症（PKU）的临床流行病学特征。

[ Objective ] To study the clinical epidemiological features of neonatal disease screening , namely congenital hypothyroidism ( CH ) and phenylketonuria ( PKU ) .

胎儿甲减的病因主要有先天性甲状腺功能减退（CH）、药物性甲减、缺碘和母亲患自身免疫性甲状腺疾病（AITD）。

Major causes of fetal hypothyroidism are congenital hypothyroidism , drug-induced hypothyroidism , iodine-deficient hypothyroidism and maternal hypothyroidism because of autoimmune thyroid disease ( AITD ) .

亚临床甲状腺功能减退组患者包含四种组成，其中单纯TSH升高和单纯FT4降低患者比例较高。

There are four components of subclinical hypothyroidism , and in them groups of patients with simple TSH elevation & simple FT4 decreasing have higher ratios .

结果先天性甲状腺功能减退症新生儿9例患儿IGF-Ⅰ、IGFBP-3水平显著降低，经治疗后甲状腺功能逐渐恢复正常；

Results Serum IGF-I , IGFBP-3 levels in 9 CH newborn group were lower , and they were normal after thyroxine substitute therapy .

目的开展新生儿先天性甲状腺功能减退症（CH）的筛查及临床治疗，以期降低残疾儿童的发生率，提高我国人口素质。

Objective To develop the newborn screening and treatment for congenital hypothyroidism ( CH ) in order to prevent the children from growth and mental retardation and to improve the population quality in China .

维吾尔族MCI组与对照组间亚临床甲状腺功能减退率比较，SCH率MCI组高于对照组，差异有统计学意义（P0.05）。

Uygur MCI between ergometry subclinical hypothyroidism rate quite , SCH rate higher than those in the control group , the differences of MCI was statistically significant ( P 0.05 ) .

目的加深对甲状腺功能减退症与阻塞性睡眠呼吸暂停低通气综合征（OSAHS）之间关系的认识，以提高诊断和治疗水平。

Objective To explore the relationship between obstructive sleep apnea-hypopnea syndrome ( OSAHS ) and hypothyroidism , and to discuss the proficiency of diagnosis and treatment .