氧化性损伤

食物脂肪对大鼠DNA氧化性损伤的影响

Effects of Dietary Fat on Oxidative Damage of DNA in Rats

DNA氧化性损伤的非酶性快速修复可能存在于细胞中

Non-enzymatic Fast Repair of DNA Oxidative Damage May Exist in Cells

山稔子提取物对体外DNA氧化性损伤的保护作用

Protective Effect of Fructus Rhodomyrti on H_2O_2-induced DNA Damage in Vitro

大量研究表明DNA氧化性损伤与肿瘤的发生关系密切。

Several studies have described that oxidative DNA damage can induce cancer .

而氧化性损伤可能是DNA损伤的机制之一。

Oxidative damage might be one of the main mechanisms of DNA damages .

骨关节病软骨细胞DNA氧化性损伤

Oxidative DNA damage of cartilage in osteoarthrosis

新型DNA电化学传感器的研制及其用于DNA氧化性损伤检测的研究

Preparation of a Novel DNA Electrochemical Sensor and Its Application to Detection of DNA Oxidative Damage

维生素E、C对紫外线辐射致皮肤细胞氧化性损伤的保护作用

The Protecting Effects of Vitamin E and C on Oxidizing Damage of Skin Cell by Ultraviolet Lights

目的探讨摄入不同脂肪含量食物对大鼠DNA氧化性损伤作用的影响。

Objective To explore the effects of different levels of dietary fat on oxidative damage of DNA in rats .

活性氧在生物大分子如DNA、蛋白质等氧化性损伤中起着非常重要的作用。

Active oxygen has an important role in the oxidative damage of biomacromolecules for example DNA , protein and so on .

脂质过氧化性损伤及DNA损伤可能是甲醛引起小鼠中枢神经系统损伤的重要机制。

Lipid peroxide and DNA damage might be the important mechanisms of central nervous system function damage in mice induced by formaldehyde .

但不改变细胞生存环境的pH值和温度，不产生氧化性损伤。

While , ACIF does not change the pH value and temperature of cell survival environment , no oxidative damage was produced .

外源性H2S对大鼠截肢创伤应激后心肌炎性及氧化性损伤的保护机制研究

Protective mechanism of exogenous hydrogen sulfide on inflammatory and oxidative damage of myocardium due to stress after amputation in rats

已知细胞中DNA氧化性损伤主要通过碱基切除修复（BER）来完成，许多修复酶参与了这一修复过程。

The DNA oxidative damage is believed that it is repaired mainly by the base excision repair ( BER ) mechanism with many repairing enzymes .

生物体在受到紫外照射时，常因在核酸水平上形成嘧啶二聚体导致DNA的氧化性损伤，具有强烈的致死作用。

UV radiation ( UV-B , UV-C ) can induced serious damage in organism . The major damage on the nucleic acid level is DNA biologic oxidation damage : formation of pyrimidine dimmers .

iNOS过表达可导致内源性NO产量增高，进而对胚胎造成氧化性损伤。

Overexpression of iNOS gene resulted in high product of nitric oxide ( NO ) and finally induced embryos to occur to oxidative damage .

尽管它们在体内的半衰期很短，但可以与DNA、蛋白质和多元不饱和脂肪酸作用造成DNA链断裂和氧化性损伤、蛋白-蛋白交联、蛋白-DNA交联和脂质过氧化。

Though radicals has a very short time of half-life , it can react with DNA , protein and PUFA , which can make DNA chain rupture and damage , coupling of protein-protein , coupling of protein-DNA and fat anti-oxidation .

表明后注入SOD可直接清除重要脏器细胞内因化疗药物产生的过量ROS，还可提高其它抗氧化酶活性而协同清除化疗药物产生的过量ROS，从而避免正常器官的氧化性损伤。

It can be inferred that the oxidation damage of normal tissue can be avoided with scavenge of excessive ROS and increase of anti-oxidative enzymes by SOD in the chemotherapy .

结论：MDF对氧自由基有清除作用，并能预防性对抗超氧阴离子自由基引起的氧化性损伤，对肝线粒体的氧化性损伤有保护作用。

Conclusion : It indicated that MDF could scavenge oxygen free radicals and was capable of prophylactically antagonizing against the oxidative injury by superoxide anion .

研究结果为CS2对生物大分子的氧化性损伤假说提供了直接证据。

Results presented in this paper may support the direct evidence for the hypothesis of CS2 oxidative injury to biologic tissue .

幽门螺杆菌致胃上皮细胞株GES-1和胃癌细胞株SGC-7901的氧化性损伤

Helicobacter pylori infection induces oxidative DNA damage in human gastric epithelial cell line GES-1 and human gastric cancer cell line SGC-7901

目的研究食用油烟颗粒提取物（COF）对大鼠肺Ⅱ型细胞的氧化性损伤作用并探讨其作用机制。

Objective To study possible mechanisms of oxidative damages in rat lung type ⅱ cells induced by cooking oil fume ( COF ) .

目前烟雾吸入性急性肺损伤（ALI）/急性呼吸窘迫综合征（ARDS）的发病机制尚未完全明确，可能与烟雾所致的氧化性损伤、肺表面活性物质变化、细胞因子改变、细胞凋亡的发生有关。

The pathogenesy of smoke inhalation acute lung injury / acute respiratory distress syndrome ( ALI / ARDS ) is not completely clear , perhaps concerned with oxidative damage , the change of pulmonary surfactant and cytokine , and apoptosis .

表明芹汁具有拮抗CCl4所致肝脏氧化性损伤的作用，并且在相同剂量下叶汁作用强于梗汁。

These results revealed that the celery had the powerful antagonism to the oxidative damage of liver by CCl 4 . Moreover at the same dose , the effect of the leaf juice was stronger than that of the stem juice .

褪黑素对苯妥英诱发胚胎脑组织氧化性损伤的拮抗作用

Melatonin antagonizes the oxidative damage initiated by phenytoin in embryonic brain

肾小管细胞氧化性损伤模型的建立

The experimental model in H_2O_2 - induced renal epithelial cell injury

溶血磷脂酸诱导小脑颗粒细胞氧化性损伤与凋亡

Lysophosphatidic acid induced oxidative damage and apoptosis in cerebellar granule cells

慢性甲醛吸入对小鼠肝脏的氧化性损伤

Oxidative damage induced by chronic formaldehyde inhalation in liver of mice

血管内皮细胞的氧化性损伤机理

The Mechanisms of Endothelial Cell Injury Induced by Oxidative Stress

煤烟颗粒提取物对大鼠肺细胞的氧化性损伤作用

Oxidative Stress Damages Induced by Soot on Rat Pulmonary Cells