核苷

hé gān
  • nucleoside
核苷核苷
核苷[hé gān]
  1. 含萘直链多胺化合物的荧光pH效应及核苷磷酸盐的分子识别

    The pH Effect on the Fluorescence of Linear Poly-amino-compounds and the Recognition of Nucleoside Phosphates

  2. 拉米夫定是一种核苷类似物,是HBVdna聚合酶的抑制剂,已在临床上广泛用于抑制乙肝病毒的复制。

    Lamivudine , a nucleoside analogue , is an inhibitor of HBV DNA polymerase .

  3. 从胸腺DNA酶解液用阳离子交换树脂分离脱氧核苷

    The separation of deoxyribonucleosides from enzymatic hydrolysate of thymus DNA by cation exchange resin chromatography

  4. DNA核苷酸碱基序列分析软件的编写和应用

    Editing software of analyzing nucleotide sequence

  5. 免疫亲和层析法分离纯化含次黄嘌呤核苷mRNA

    Immunoaffinity purification of inosine-containing mRNA on column of anti-inosine antibody

  6. 黑柄炭角菌不同组织的核苷成分HPLC测定

    HPLC Determination of Nucleosides in Different Tissues of Xylaria nigripes

  7. 冬虫夏草发酵菌丝体中主要核苷及核酸碱基的HPLC测定

    HPLC Determination of Main Nucleoside and Nucleic Acid Base in Mycelia of Cordyceps

  8. 提示茯苓素对核苷转运的作用可能是抑制DNA合成的一个重要环节。

    We suggest that poriatin might inhibit nucleoside uptake into the cells , thus causing inhibition of DNA biosynthesis .

  9. 影响核苷类似物疗效的HBV基因结构与功能的研究

    The Study of Genes and Structures of HBV Influencing the Efficiency of Nucleoside Analogue Drug

  10. 内源性核苷、核苷酸通过嘌呤与嘧啶受体(P受体),参与机体组织器官多种功能的调节。

    Endogenous nucleoside and nucleotide mediate a lot of functions via cell surface P receptors ( receptors for purines and pyrimidines ) in many organs .

  11. 肝脏DNA合成率用3H标记胸腺嘧啶核苷(3HTDR)掺入法测得。

    The rates of DNA synthesis were detected by 3H-TdR method .

  12. 人体胸腺嘧啶核苷激酶不完全cDNA的分离、结构分析和表达

    Isolation , Preliminary Characterization and Expression of a Near Full-length cDNA for Human Thymidine Kinase

  13. 用氚&胸腺嘧啶核苷放射自显影方法,观察到RⅡ对小鼠前胃上皮细胞DNA合成有明显的抑制作用。

    Autoradiography using H ~ 3-thymidine showed marked inhibitory effect of R ⅱ on DNA synthesis in the forestomach epithelium of mice .

  14. 光诱导氧自由基与嘧啶碱基及其核苷反应的ESR研究

    ESR Study on reaction of light-induced oxygen radicals with pyrimidine bases and nucleosides

  15. 初步药理实验显示:人工培养蛹虫草中总核苷在体内和体外对肝癌H(22)细胞有一定的抑制作用。

    The pharmacological tests showed that there was the inhibition action of nucleosides in cultured stroma on the hepatocarcinoma H_ ( 22 ) cell .

  16. 用~3H-胸腺嘧啶核苷掺入抑制试验检测人外周血NK细胞活性

    Study on inhibition of ~ 3h-tdr incorporation assay for NK cell activity of human peripheral blood

  17. 我们利用氨基核苷嘌呤霉素(PAN)肾脏损伤模型在小鼠永生足细胞中检验了这些可能性。

    We tested these possibilities utilizing the puromycin aminonucleoside ( PAN ) model of renal injury in immortalized mouse podocytes .

  18. 核苷类似物联合人工肝治疗可加快肝功能好转,缩短病程,降低病死率,降低血清HBVDNA水平。

    Treating with nucleosides plus ALSS could accelerate the amelioration of liver function , shorten course of disease , decrease mortality and HBV DNA level .

  19. 用免疫细胞化学法定位溴脱氧尿嘧啶核苷(BrdU)掺入到肾小管上皮细胞DNA内;

    Using immunocytochemistry to investigate bromodeoxyuridine ( BrdU ) incorporation of DNA in renal tubular epithelial cells of rats ;

  20. 并以3H胸腺嘧啶脱氧核苷(3HTDR)细胞内掺入法评价DNA合成量。

    3H TdR incorporation assay in vitro taken was used to evaluate the amount of DNA synthesis .

  21. BrdU是一种核苷类似物,在细胞周期的S期可参入DNA链。

    BrdU is a analogous of nucleotide which can be incorporated into DNA chain in S phase of cell cycle .

  22. 动物处死前1h注射尿嘧啶脱氧核苷(BrdU),标本行免疫组化染色,显微镜下计数BrdU标记的成纤维细胞样细胞。

    Immunohistochemical method was applied to count the BrdU - labeled fibroblast-like cells .

  23. 复合核苷氧钒配合物(VRC)的合成及对RNA酶的抑制效应

    Synthesis of vanadyl-ribonucleoside complexes ( VRC ) and their inhibition on ribonuclease activity

  24. 二磷酸核苷与其特异性位点结合,不仅降低通道对ATP的敏感性,而且可直接诱导通道开放。

    Intracellular nucleoside diphosphate can antagonize the ATP induced inhibition of the channel opening and stimulate the channel to open .

  25. 用还原型尼克项胺腺嘌呤二核苷磷酸黄递酶反应,结合乙酸胆碱酯酶组织化学技术,观察了SD大鼠背根神经节,发现背根神经节内存在有四种不同显色的神经元。

    By means of combining NADPH-d with AChE histochemical technique . we studied the ganglionic neurons in SD rats ' dorsal root .

  26. 新非核苷喹诺酮类HIV-1逆转录酶抑制剂的CoMFA研究

    The CoMFA study on quinolones as novel inhibitors of HIV-1 reverse transeriptase

  27. 癌变过程中酪氨酸转氨酶(TAT)和5′-核苷磷酸二酯酶(5′-NPDase)的变化

    Changes of tyrosine transaminase activity and nucleotide 5 ' - phosphodiesterase activity during carcinogenesis

  28. 利巴韦林(Ribavirin)是一种嘌呤核苷类似物,具有广谱抗病毒作用。对多数DNA、RNA的复制有抑制作用。

    Ribavirin , an antiviral agent of nucleoside analog , has wide efficacy against virus and restrains lots of DNA and RNA copy .

  29. 3H-胸腺嘧啶脱氧核苷(3H-TdR)掺入法测定单向混合淋巴细胞反应。

    Tritiated thymidine ( 3H-TdR ) was used to measure mixed lymphocyte response .

  30. PRINS反应的基本物是DNA聚合酶和引物原位扩展反应中的标引核苷。缩氨酸核酸探针是合成的不带电聚酰胺主链的DNA类似物。

    The PRINS reaction is based on the use of a DNA polymerase and labeled nucleotide in an in situ primer extension reaction .