支气管平滑肌痉挛

研究表明硝苯啶能有效地抑制缺氧性肺血管收缩和支气管平滑肌痉挛，使Qs/Qt降低，PaO2上升，没有导致VA/Q的恶化。

It is concluded that nifedipine can effectively suppress hypoxic pulmonary vascular constriction and bronchial muscular spasm so that Qs / Qt is decreased and PaO2 increased , not accompanied with variations in VA / Q.

对组胺引起的支气管平滑肌痉挛有强烈的对抗作用，可使组胺量效曲线右移，其pA2为（8.22±0.22）。

Cetirizine inhibited the bronchi muscle contract induced by histamine obviously , and caused histamine dose effect curve a right shift , the pA 2 was ( 8.22 ± 0.22 ) .

初步药理实验表明：所合成的17个化合物（CX-01至CX-17）对组胺诱导的离体豚鼠支气管平滑肌痉挛均具有不同程度的松弛作用。

And all compounds were identified by IR , 1H-NMR and MS. Primary pharmacological tests showed that all seventeen compounds ( CX-01 to CX-17 ) had relaxing activity on the contracting bronchial smooth muscle of guinea-pigs induced by histamine .

结果哮喘组细支气管平滑肌痉挛，管腔内较多炎性渗出物，管壁内大量炎症细胞浸润；

Results There were marked smooth muscle spasm , inflammatory cell infiltration and a large amount of exudate in the airway lumen in the asthma group .