土贝母

方法该文查阅了大量关于土贝母研究的中外文献资料，从化学成分、药理活性、制剂开发等方面对其进行比较全面地综述。

MethodsReferring to a large number of domestic and foreign literatures , the chemical compositions , pharmacological activities and development of preparations of Bolbostemma paniculatum were reviewed .

土贝母提取物&结晶E对HL-60细胞的诱导分化作用

Induction of differentiation of HL-60 cell by extracting bolbostemma paniculatum franquet-crystal-E

土贝母苷甲对人红白血病细胞K562的诱导分化作用

Differentiation-inducing activity of tubeimoside I in human erythroleukemic K562 cells

方法：采用台盼蓝拒染法检测土贝母苷甲对K562细胞增殖的影响；

METHODS : The growth inhibitory activity of tubeimoside I was evaluated with K562 cells .

用MTT法检测磁场结合中药（土贝母皂甙、白屈菜红碱和血根碱）对K562细胞的杀伤作用。

The kill effects of SMF cooperated with Chinese herbs on K562 cells were tested by MTT test .

土贝母皂苷对HL-60细胞周期作用的研究

Effect on cell cycle in human promyelocytic leukemia cells ( HL-60 ) treated with tubeimosides

土贝母苷甲诱导人鼻咽癌细胞CNE-2Z凋亡

Apoptosis of Human Nasopharyngeal Carcinoma CNE-2Z Cells Induced by Tubeimoside ⅰ

土贝母皂苷对人低分化上皮样鼻咽癌细胞（CNE-2Z）微管的作用

Effects of tubeimoside isolated from Bolbostemma paniculatum on microtubule in CNE-2Z cells

目的：应用土贝母皂苷（下称皂苷）作用于人早幼粒白血病细胞（HL-60），研究皂苷抗肿瘤作用的分子机制。

OBJECTIVE : To explore the molecular mechanism of antitumor effect of tubeimosides by treating human promyelocytic leukemia cells ( HL-60 ) .

本研究旨在探讨土贝母苷甲对小鼠B16黑色素瘤（B16）和Lewis肺癌（LLC）转移的影响。

This study was designed to investigate the effects of tubeimoside 1 on the metastases of mouse B16 melanoma and lewis lung carcinoma .

土贝母皂甙对家兔单纯疱疹病毒性角膜炎的作用

Experimental research of tubeimoside against herpes simplex keratitis in rabbits

其中皂苷类含量较大，为土贝母的主要活性成分。

Saponins are main active ingredients for its large content .

土贝母水提物对体外培养人肝癌细胞增殖及代谢的影响

Effects of BPF extracts on proliferation and mitochondria metabolism of human hepatoma SMMC-7721 cells

土贝母化学成分及抗肿瘤活性研究

Studies on the Chemical Constituents from the Bulbs of Bolbostemma Paniculatum and Their Antitumor Activities

土贝母、贯叶连翘组织培养及其有效成分分离提取的研究

Study on tissue culture and effective component separation and extraction of Bolbostemma Paniculatum ? and Hypericum perforatum

土贝母中含有皂苷类、甾醇及其苷类和酯类、生物碱类等多种化学成分。

Tu-Bei-Mu contains multiple components , such as saponins , sterol with its glycosides and esters , alkaloids .

研究中药土贝母微囊作为血管栓塞剂的有效性、安全性及相关特性。

To study the efficacy , safety and related characteristics of ethylcellulose microcapsules containing tubeimoside as a vascular embolization agent .

结果：土贝母苷Ⅰ、Ⅱ和Ⅲ是来自同一植物的齐墩果烷型三萜皂苷天然类似物。实验证实，它们都具有抗炎、抗瘤和抗促瘤效果。

RESULTS : Tubeimosides ⅰ , ⅱ , and ⅲ are all natural analogues of oleanane type of triterpenoid saponins from the same medicinal plant , and all show anti-inflammatory , antitumor , and antitumor-promoting effects .

土贝母苷甲（2、3mg/kd/d×14）和环磷酰胺（50mg/kd/w×2）治疗组小鼠的肝转移抑制率分别为46.3%、52.0%和54.7%。

The liver metastasis inhibition rates of lewis lung carcinoma by tubeimoside 1 ( 2 , 3mg / kg / d × 14 ) and cyclophosphamide ( 50mg / kg / w × 2 ) were 46.3 % , 52.0 % , and 54.7 , respectively .