内脏感觉

目的：观察应用5HT4受体部分激动剂替加色罗（tegaserod）对大鼠直肠扩张反应的影响和脊髓神经元性一氧化氮合酶（nNOS）表达的变化，探讨替加色罗对内脏感觉的影响机制。

Objective : To examine the effects of 5 HT4 receptor partial agonist tegaserod on response to rectal distention ( RD ) and on nNOS expression in spinal cord , and to investigate the mechanism of tegaserod influencing visceral sensation .

传统束缚应激动物模型内脏感觉的新评价

The evaluation of visceral sensation in traditional restraint wrap stress animal model

哮喘豚鼠内脏感觉传入部位P物质含量的变化

The alterations of substance P levels in the viscerosensory afferent sites of the asthmatic guinea pig

非糜烂性胃食管反流病患者食管内脏感觉过敏与P物质表达的关系

Relationship between esophageal visceral hyperesthesia and expression of substance P in LES of patients with non-erosive gastro-oesophageal reflux disease

实验性支气管哮喘豚鼠肺和内脏感觉传入系统蛋白激酶C的表达及神经生长因子的调节作用

The expression of protein kinase C and the regulatory effect of nerve growth factor in the lung and the visceral sensory afferent system of asthmatic guinea pigs

REM睡眠剥夺对大鼠内脏感觉影响的研究

The effects of rapid eye movement sleep deprivation on visceral sensitivity in rats

电针抗胃炎性痛对内脏感觉c-fos及NOS阳性神经元的影响

Changes of c-fos and Nitric Oxide Synthase Activities in the Visceral Afferent Pathway during Gastric Inflammation Pain and following Electroacupuncture

结论REM睡眠剥夺降低大鼠的内脏感觉功能，且与睡眠剥夺时间相关。

Conclusion The visceral sensitivity in rats would be affected by REM sleep deprivation together with time .

中缝背核c-fos、5-HT在IBS内脏感觉过敏机制中的作用

Role of C-fos and 5-HT of Dorsal Raphe Nucleus in the Pathogenesis of Visceral Hypersensitivity in Irritable Bowel Syndrome

分布于肌内，粘膜下层和上皮基部的AChE阳性神经中，尚含有内脏感觉神经纤维。

Among the AChE positive nerve fibers distributed in the muscle , submucosa and epithelial bases , there were visceral sensory nerve fibers .

提示FV的发病可能涉及情感认知、内脏感觉、内脏运动三方面的共同作用。

Abnormalities of cognition-emotion , visceral sensory and motor functions could contribute to the pathogenesis of FV together .

IBS主要肠道表现包括肠道动力、内脏感觉以及肠黏膜分泌与屏障功能异常。

The disorder of colonic motility , sensation , mucosal secretion and epithelial barrier function are main pathophysiologic manifestation of IBS .

本研究显示国内IBS病人中枢内脑岛皮质、额前皮质可能是参与内脏感觉的主要部位。

In this study , IC and PFC of the IBS patients are the major positions in the CNS processing of visceral perception .

有腹部症状的腹泻型IBS患者饮冰水后的症状轻重与内脏感觉阈值呈直线负相关。

A negative linear correlation was found between the symptoms of diarrhea-predominant IBS patients and the visceral perception threshold after ice water drinking .

结肠粘膜低度炎症诱发小鼠结肠PAR-2活化和内脏感觉过敏

Low Grade Mucosal Inflammation Activated the Colonic PAR-2 and Visceral Hypersensitivity in Mice

目的研究非糜烂性胃食管反流病（NERD）患者食管内脏感觉过敏与食管下端括约肌（LES）黏膜中P物质（SP）免疫反应阳性产物表达之间的关系。

Objective To investigate the correlations between esophageal visceral hyperesthesia and the expression of substance P ( SP ) immunoreactive fibers in the lower esophageal sphincter ( LES ) .

结果提示5－HT对DCN内盆内脏感觉信息的传递可能具有调控作用。

The present results suggest that 5HT may be involved in the modulation of sensory information from the pelvic organs in the DCN .

而应激又可以引起内脏感觉异常，尤其是应激所致的焦虑似乎与IBS的内脏高敏关系最为密切，但确切的发生机制尚不清楚。

Stress may lead to visceral sensitivity abnormalities , especially anxiety is likely to be closely associated with visceral hypersensitivity , but the definite mechanism is unclear .

方法：利用免疫组织化学和Western印迹方法，观察生理盐水组、单纯致敏组、哮喘组和地塞米松组豚鼠肺及内脏感觉传入系统（C7T5脊神经节及对应的脊髓后角）NGF表达的变化。

Methods : The alterations of NGF expression were observed by means of immunohistochemistry and Western blot in the lung , C_ 7-T_ 5 spinal ganglia and the corresponding dorsal horn of the spinal cord of all guinea pigs .

目的探讨直肠内温度及压力变化对肠易激综合征（IBS）患者内脏感觉阈值的影响，进一步研究IBS的发病机制。

Objective To observe the effects of rectal thermal - and pressure - stimuli on visceral perception thresholds in patients with irritable bowel syndrome ( IBS ) and investigate its pathogenesis .

哮喘小鼠肺内及内脏感觉传入系统SH2-Bβ的表达

The expression of sh2-b β in the lung and visceral sensory afferent system of the asthmatic mice

目前多数学者认为IBS是由多因素诱发的疾病，这些因素包括内脏感觉异常、肠道动力异常、感染、免疫、精神心理因素、基因和肠道菌群失调等。

Now most researchers consider that IBS has a multifactorial etiology , which involves abnormal gastrointestinal motility , visceral hypersensitivity , infection , immunity , psychological factor , gene and enteric dysbacteriosis and so on .

根据本文结果并结合以前的工作推断，盆腔内脏感觉经DCN、IM和Ⅰ层的神经元中继后，投射至PBL。

According to the present and previous researches , the authors conjecture that , the secondary fibers of visceral sensation of the pelvic organs originate from the neurons of DCN , IM and lamina I and project into the PBL .

目的：探讨地塞米松对哮喘豚鼠肺及内脏感觉传入系统（C7T5脊神经节及对应的脊髓后角）神经生长因子（NGF）表达的影响。

Objective : To explore the effect of dexamethasone on the expression of NGF in the lung and the visceral sensory afferent system ( C_ 7-T_ 5 spinal ganglia and the corresponding dorsal horn of the spinal cord ) of asthmatic guinea pigs .

腹泻型肠易激综合征（IBS-D）是我国IBS最常见的类型，其发病机制复杂，包括内脏感觉过敏、肠道动力增强、脑肠作用异常、神经-内分泌-免疫网络异常等。

Diarrhea-predominant IBS is the major type of IBS in China , the pathogenetic mechanisms of IBS-D are complicated , including visceral hyperesthesia , enhanced colonic motility , brain-gut dysfunction , abnormal neuro-immuno-endocrine network and so on .

结论：HIFU可以立刻同时完善地阻断交感神经和内脏感觉神经的传导，乙醇可立刻阻断交感神经的传出神经纤维，对内脏感觉神经的传导阻滞程度较HIFU差。

Conclusions : HIFU can block the conduction of sympathetic nerve and visceral afferent fibre completely at once . Alcohol can block sympathetic efferent nerve just as HIFU , but the degree in blocking the conduction of visceral afferent fibre is less than HIFU .

在REM睡眠剥夺的第12h、24h、48h、72h行结直肠扩张（CRD），观察大鼠的腹壁回撤反射（AWR）以测定内脏感觉功能。

The rats were received colorectal distension ( CRD ) on hour 12 , 24 , 48 and 72 under REM sleep deprivation . The abdominal withdrawl reflex ( AWR ) scores of the 3 groups were observed to measure their visceral sensitivity .

两组大鼠均在第1次灌肠后的第3、6、9、12、15、18天行结直肠气囊扩张（CRD），观察大鼠的腹壁回撤反射（AWR）测定内脏感觉功能。

They were received colorectal distension ( CRD ) on day 3,6,9,12,15 and 18 after the first enema . The abdominal withdrawl reflex ( AWR ) scores of the 2 groups were observed to measure their visceral sensitivity .

背景：血氧水平依赖性功能性磁共振成像（BOLD-fMRI）技术近来被广泛应用于人体内脏感觉的研究，而非糜烂性反流病（NERD）的发生与内脏感觉高敏有密切关系。

Background : Recently blood oxygen level dependent ( BOLD ) - functional magnetic resonance imaging ( fMRI ) technique was extensively used in human visceral perception research study . It has been accepted that visceral hypersensitivity is closely related with the pathogenesis of non-erosive reflux disease ( NERD ) .

胃肠功能性疾病：是胃肠动力障碍？还是内脏感觉异常所致？

Functional gastrointestinal disorders : abnormality in motility or visceral sensitivity ?