二硫键

它由A和B两条多肽链组成，其间通过二硫键相连接。

The toxin protein consists of two chains linked by a disulfide bond .

晶状体生化的研究&亚硒酸钠诱发大鼠白内障晶状体中巯基、二硫键及维生素C的含量

The study of lens biochemistry the levels of sulfhydryl groups , disulfide bond and vitamin C in lens of rat cataract induced by sodium selenite

如果二硫键被破坏，分子成为A和B两个片段。

If disulfide bonds are broken , the molecule can be split into two fragment .

降钙素是一种32个氨基酸组成的多肽内激素，其蛋白结构的N端为二硫键，C端为脯胺酰胺基团。

Calcitonin is a 32-amino-acid-long peptide with an N-terminal disulfide bridge and a C-terminal polyamide residue .

人类一条新的类蛋白质二硫键异构酶cDNA的克隆和表达

Cloning Expression of a Novel Human Protein-Disulfide Isomerase Like cDNA

蓖麻毒素蛋白来源于蓖麻籽中，由A、B两条肽链通过二硫键连接而成。其中，A链为效应链，具有糖苷酶活性，能使核糖体失活；

Ricin toxin is derived from castor beans and composed of two glycoproteins chains A and chains B linked by a disulfide bond .

Ⅱ型RIP是通过二硫键连接的双链蛋白。

And tow-peptide chain protein s , type II RIP .

二硫键稳定单链抗体B3（ds-scFv）靶向超抗原SEA的制备及活性鉴定

Preparation and Evaluation of Disulfide - Stabilized Single - Chain Antibody B3 ( ds - scFv ) Targeted SEA

重组单链胰岛素（PIP）含有3对二硫键。

Recombinant single chain insulin ( PIP ) contains three disulfide bonds .

对纯化步骤作了产率和纯度分析后，又就重组蛋白的分子量、N端序列、等电点、肽质量指纹图谱及二硫键位置等理化性质做了进一步鉴定。

After that , we identified the molecular weight , the N-terminal sequencing , isoelectric point , disulfide bonds , and other physical and chemical properties of the recombinant protein .

本文仅对LC固定相对蛋白折叠的贡献以及二硫键折叠的研究进展进行了全面地综述。

Contribution of stationary phase to protein refolding and disulfide bond formation was reviewed , and 76 references were cited .

风疹病毒包膜糖蛋白E1中二硫键对其细胞融合活性的影响

Effects of Disulfide Bridges in Glycoprotein E1 on the Membrane Fusion Activity of Rubella Virus

二硫键稳定的抗CD3/抗Pgp微型双功能抗体的构建、表达及活性测定

Construction and expression of disulphide stabilized anti-CD3 / anti-Pgp diabody

NR／R双向SDS-PAGE证明家蝇抗菌蛋白分子中的两个半胱氨酸残基未形成二硫键。

NR / R 2-dimensional SDS-PAGE proved that the two cysteine residues in the molecule were not engaged in intramolecular disulfide bridge .

自牛肝中纯化二硫键异构酶（PDI）。

Protein disulfide isomerase ( PDI ) was purified from bovine liver .

氨基酸序列分析表明，N端存在一长21个氨基酸的信号肽，含有形成2个链内二硫键的4个半胱氨酸。

Amino acid sequence analysis showed that the predicted protein had a leader sequence composed of 21 amino acids , and four conserved cysteines allowing the formation of two intrachain disulfide bonds .

目的探讨蛋白二硫键异构酶（PDI）的生物学功能及与微粒体的关系。

Objective To study the biological function of PDI and relationship to microsome .

并且DSC分析显示，N-巯基乙酰丝氨酸可与头发上的胱氨酸残基交换二硫键而与头发连接起来。

And the DSC analysis showed that N-thioacetyl-DL-serine could be linked to hair by changing the Sulfur-Sulfur bonds with the cystine in the hair .

而在雌核发育银鲫卵中，Ca2＋的功能和二硫键的还原作用与精核发育受到抑制之间并无直接联系。

But in ooplasm of gynogenetic crucian carp the Ca2 + and disulfide bond reduction was not directly related to the inhibition of sperm nuclear development .

哺乳动物分泌型磷脂酶A2是一组含有6-8个二硫键的，分子量为13-16kDa，水解甘油磷脂的酶。

Mammalian secretory phospholipase A2 contains 6-8 disulfide bonds with a molecular mass of 13-16 kDa . It catalyzes the hydrolysis of phospholipids .

SDSpage、RPHPLC和质谱分析都显示，经这种纯化流程提纯的蛋白有很高的纯度，且二硫键已完全正确形成。

The SDS-PAGE , RP-HPLC analysis and mass spectrometry analysis used to examine the final purified protein showed that the protein was pure and its disulphide bond was formed completely .

SEM和FTIR-ATR分析表明该联合处理羊毛纤维表面的类酯物质和胱氨酸二硫键得到有效改性。

SEM and FTIR-ATR analysis showed that the surface disulfide bonds and surface lipid were modified / removed by the combined treatments effectively .

在人IB型磷脂酶A2的所有二硫键中，11-77二硫键暴露在分子的表面，最先被还原。

The disulfide bond 11-77 in human group IB phospholipase A2 locates at the surface of the protein and was firstly reduced by DTT .

酶的等电点为4.46和4.79。非还原／还原（NR／R）单向、双向SDS-PAGE显示酶分子含有链内二硫键。

Isoelectric focusing study showed that pI of the enzyme were 4.46 and 4.79 . NR / R single and two dimensions SDS-PAGE found that the enzyme contained intrachain disulfate link .

Raman光谱中通过S-S和C-C伸缩振动特征谱带的变化，说明脉冲电场对巯基和二硫键有一定的影响；通过酪氨酸特征振动频率的变化情况，说明脉冲电场对疏水相互作用有一定的影响。

Changes in S-S and C-C stretching vibration frequency by Raman spectra indicated that PEF have certain effects on sulfhydryl and disulphide bond .

二硫键稳定的双特异diabody的构建及表达

Construction and expression of disulphide stabilized bispecific diabody

防御素（defensin）是分子量为4-5KD、含六个半胱氨酸、三对二硫键的阳离子抗菌多肽，包括α-防御素和β-防御素。

Defensins are cationic antimicrobial peptides with six cysteine and three pairs of disulfide bonds , including a-defensin and β - defensin .

目的探讨脑组织二硫键异构酶（PDI）的变化在脑缺血&再灌注损伤（CIRI）中的意义。

Objective To investigate the changes and significance of protein disulfide isomerase in rats with ischemic brain damage .

DTT还原膜蛋白二硫键后再用NEM，DTNB修饰巯基，胰岛素结合活性进一步下降。

Modification of protein thiol with NEM or DTNB after reduction with DTT leads to further decrease of specific binding .

C型钠尿肽（C-typenatriureticpeptide，CNP）作为钠尿肽家族的第三成员，它是由22个氨基酸残基组成的多肽，含有一个二硫键在内的17个氨基酸环。

C-type natriuretic peptide ( CNP ) is a third member of natriuretic peptides family ( NPs ) . The molecule incorporates a 17-residue intra-molecular disulfide loop , common to all natriuretic peptides .