髓样癌

结果表明，乳头状癌、滤泡性癌和髓样癌的p53蛋白表达阳性率分别为100%、81.3%和85.7%；

The results showed that the positive rates in papillary adenocarcinoma , follicular adenocarcinoma , and medullary carcinoma were 100 % , 81.3 % and 85.7 % respectively .

结果Ecadherin蛋白的表达强度，典型髓样癌高于非典型髓样癌（P<0.05）；

Results The staining intensity of E cadherin oncoprotein typical medullary carcinoma was significantly higher than those in a typical medullary carcinoma ( P < 0.05 ) .

人甲状腺髓样癌内凋亡细胞检测和bcl-2、p53及Ki-67的免疫组化研究

Detection of apoptotic cells and immunohistochemical study of bcl-2 , p53 and Ki 67 in human medullary thyroid carcinoma

散发型甲状腺髓样癌RET基因突变的研究

Study on mutation of RET gene in sporadic medullary thyroid carcinoma

~（99）Tc~m（V）-DMSA与~（99）Tc~m-MIBI亲肿瘤显像在诊断甲状腺髓样癌中的对比

Comparison of ~ ( 99 ) Tc ~ m ( V ) - DMSA and ~ ( 99 ) Tc ~ m-MIBI Scintigraphy in Medullary Thyroid Carcinoma

VEGF-C在甲状腺髓样癌和甲状腺滤泡状癌中的表达差异

Comparison of expression rate of VEGF-C between medullary thyroid carcinoma and follicular thyroid carcinoma

bcl-2、bax、CD57在乳腺髓样癌中表达及其临床意义的研究

Studies of Clinical Significance of Expression of bcl-2 、 bax and CD57 in the Medullary Breast Carcinoma

目的：探讨影响甲状腺髓样癌（MTC）预后的因素。

Purpose : To explore the prognostic factors of medullary thyroid carcinoma ( MTC ) .

目的研究甲状腺髓样癌（MTC）的RET原癌基因突变情况。

Objective To detect the mutations of RET proto-oncogene in patients with medullary thyroid carcinoma ( MTC ) .

目的探讨甲状腺髓样癌（MTC）的不同手术方式的临床效果。

Objective To investigate the clinic effect of different operative approaches on medullary thyroid carcinoma ( MTC ) .

方法：在21例甲状腺髓样癌内，用DNA末端标记方法检测凋亡细胞和用免疫组织化学技术检测bcl－2、p53及Ki－67的表达。

Methods Detection of apoptotic cells was used by DNA nick end labeling method and detection of bcl 2 , p53 and Ki 67 by immunohistochemical ABC method .

CD57抗原表达与乳腺髓样癌预后

The Expression of Antigen CD57 and Prognosis of Typical Medullary Carcinoma

目的：研究散发型甲状腺髓样癌酪氨酸激酶受体基因（RET）的突变情况。

Objective : To explore the mutation of receptor tyrosine kinase ( RET ) gene in sporadic medullary thyroid carcinoma .

2例甲状腺髓样癌患者呈强阳性，病灶放射性分布类似CT所见，而其余甲状腺良恶性病变几乎均阴性。

The lesions of 2 patients with medullary thyroid carcinoma had strong positive uptake and the pattern of radioactive distribution were similar to that of CT scan , Uptake of the other benign and malignant diseases of thyroid were almost negative .

对髓样癌常规进行RET基因检测，对家族中RET基因携带者行预防性甲状腺全切除术。

Prophylactic total thyroidectomy should be performed to those who are RET gene carriers and have positive family history with medullary thyroid cancer .

甲状腺滤泡癌细胞胞核的PU值小于乳头状癌组，大于未分化癌和髓样癌组，差异有统计学意义（P<0.01）；

The TTF-1 PU in nuclei of thyroid follicular adenocarcinoma was lower than that of papillary adenocarcinoma , but higher than those of undifferentiated and medullary carcinomas ( P < 0.01 ) .

此外，发现支气管腺癌、甲状腺嗜酸性腺瘤、甲状腺髓样癌和胆管细胞癌S-100蛋白阳性。

Especially , we have demonstrated S-100 protein in eosinophilic adenoma and medullary carcinoma of thyroid gland , adenocarcinoma of bile duct and bronchiolar adenocarcinoma .

不同组织学类型TAM抑制率实验似有差异，髓样癌的阳性检出率较浸润性导管癌高。

The TAM positive rate in medullary cancer was higher than that in other pathologic types of breast tumors and it was the lowest in ductal cancers .

目的探讨存活素（survivin）反义寡核苷酸（Antisenseoligodeoxyribonucleotide，ASODN）在人甲状腺髓样癌裸鼠模型中的抑瘤作用。

Objective To evaluate the inhibitory effects of survivin antisense oligodeoxyribonucleotide ( ASODN ) on human medullary thyroid cancer ( MTC ) inoculated into the nude mouse .

对1例患2B型多发内分泌腺瘤女童的复发甲状腺髓样癌所实施的123I间碘苄胍射频引导下的导航手术

Iodine 123 metaiodobenzylguanidine radio-guided navigation surgery for recurrent medullary thyroid carcinoma in a girl with multiple endocrine neoplasia type 2B

结果表明：单纯癌、浸润性导管癌、硬癌等癌组织中，CEA阳性率及平均CEA强度均明显高于乳头状癌、髓样癌、髓样癌伴大量淋巴细胞浸润。

The positive rate and density of CEA in carcinomas of simplex , invasive ductal , and scirrhus types were significantly higher than those in papillary , medullary and medullary with abundant lymphoid infiltration carcinomas .

目的分析散发型甲状腺髓样癌RET基因第11外显子碱基序列，明确RET基因突变与散发型甲状腺髓样癌的关系。

Objective To explore the mutation of RET gene exon 11 in sporadic medullary thyroid carcinoma and to clarify the relationship between RET mutation and sporadic medullary thyroid carcinomas .

[方法]采用Envision二步免疫组织化学分析法分别检测TTF1和TG在45例常见的甲状腺良性病变和65例甲状腺癌中的表达，其中10例甲状腺髓样癌加做CT检测。

TG and TTF-1 expression were detected by Envision technique in 45 specimens of benign thyroid diseases and 65 specimens of malignant thyroid neoplasms , and CT protein was also detected in 10 specimens of medullary carcinomas .

目的：探讨CD57抗原表达与乳腺髓样癌预后关系。

Objective : To study the relation between the expression intensity of antigen CD57 and prognosis of typical medullary carcinoma , a typical medullary carcinoma and scirrhous carcinoma .

方法：选择甲状腺髓样癌10例，滤泡性腺癌、乳头状腺癌和未分化癌各3例，行免疫组化LSAB法检测。

Methods 10 cases of medullary thyroid carcinoma , 3 cases of papillary carcinoma , 3 cases of follicular carcinoma and 3 cases of undifferentiated carcinoma were studied with LSAB immunohistochemical method .

浸润性小叶癌和浸润性导管癌MMP鄄2的阳性率达86.7%，明显高于恶性程度较低的黏液腺癌和髓样癌（20.0%）以及乳腺的良性肿瘤（13.3%）。

MMP-2 was positive in 86.7 % cases with invasive duct and lobular carcinoma , which was much higher than that in mucinous carcinoma ( 20.0 % ), medullary carcinoma 20.0 % , and other benign disease ( 13.3 % ) .

乳腺髓样癌的超声诊断及其病理基础

Ultrasonographic diagnosis of breast medullary carcinoma and its basis of pathology

29例甲状腺髓样癌的病理形态与预后

Pathological Morphology and Prognosis on 29 Cases of Medullary Thyroid Carcinoma

散发性髓样癌预后较差。

Medullary carcinoma of the sporadic type carries a worse prognosis .

102例甲状腺髓样癌手术术式探讨

Study on Operation Type in 102 Patients with Medullary Thyroid Carcinoma