铜蛋白质

铜蛋白质的配位化学模拟

Coordination chemistry and the modelling of copper protein

概述了生物酶中铜蛋白质配位化学模拟的研究进展，介绍了铜离子配合物生物酶活性中心的重要铜蛋白质的结构与功能的研究方法及最新进展。

Progress in coordination chemistry and modelling of copper protein were reviewed in this paper . The main attentions were paid on the latest results and methods of structure function relationship about important copper proteins related to metal complexes .

蓝铜蛋白质的电子顺磁共振研究

Electron paramagnetic resonance examination on behaviours of the blue copper proteins

目的：分离大鼠肝脏溶酶体中铜结合蛋白质，并分析其氨基酸序列。

Objective : To isolate copper binding protein from rat liver lysosomal fraction , and to analyze its amino acid sequences .

虽然国际上有些蛋白质数据库已经收录了部分铜离子螯合蛋白质，但是收录信息不全面，更新速度较慢，蛋白质的结构信息涵盖较少是其主要缺点，DCCP则可以弥补其不足。

Although there are some databases where some samples of copper-chelating proteins have been involved , the information is not enough and the rate of update is very slowly .

铜分子伴侣是结合铜的小蛋白质，并将结合的铜运送到依赖铜的目标蛋白上。

Copper chaperone are small proteins which bind copper , deliver copper to target proteins .

铜是生物体不可缺少的一种元素，在细胞内把铜转运到含铜的蛋白质是细胞正常代谢的基本要求。

Copper is an essential element for living organism , and transporting copper to copper-dependent proteins is a basic requirement for normal cellular metabolism .